Pyrazofurin
- Product Name
- Pyrazofurin
- CAS No.
- 30868-30-5
- Chemical Name
- Pyrazofurin
- Synonyms
- PRZF;47599;A-23813;nsc143095;pyrazofurin;pirazofurin;Pyrazomycin;Pyrozofurin;compound47599;β-Pyrazofurin
- CBNumber
- CB5276253
- Molecular Formula
- C9H13N3O6
- Formula Weight
- 259.22
- MOL File
- 30868-30-5.mol
Pyrazofurin Property
- Boiling point:
- 584.4±50.0 °C(Predicted)
- Density
- 1.785±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO, Water (Slightly)
- pka
- 7.17±0.50(Predicted)
- form
- powder
- color
- white to light brown
- optical activity
- [α]/D -49 to -39°, c = 0.5 in H2O
- Stability:
- Hygroscopic
N-Bromosuccinimide Price
- Product number
- SML1502
- Product name
- Pyrazofurin
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $150
- Updated
- 2024/03/01
- Product number
- SML1502
- Product name
- Pyrazofurin
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $599
- Updated
- 2024/03/01
- Product number
- API0008977
- Product name
- PYRAZOFURIN
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $666.75
- Updated
- 2021/12/16
- Product number
- API0008977
- Product name
- PYRAZOFURIN
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $3433.5
- Updated
- 2021/12/16
- Product number
- CS-0085864
- Product name
- Pyrazofurin
- Purity
- ≥98.0%
- Packaging
- 5mg
- Price
- $400
- Updated
- 2021/12/16
Pyrazofurin Chemical Properties,Usage,Production
Uses
Geldanamycin (G304500) derivative.
Definition
ChEBI: A C-glycosyl compound that is 4-hydroxy-1H-pyrazole-5-carboxamide in which the hydrogen at position 3 has been replaced by a beta-D-ribofuranosyl group.
Biochem/physiol Actions
Pyrazofurin serves as an effective drug against HIV (human immuno virus), vaccinia virus, West Nile viral infection.
Enzyme inhibitor
This pyrimidine nucleoside (FW = 261.23 g/mol), also known as pyrazomycin, exhibits antineoplastic activity and inhibits cell proliferation and DNA synthesis in cells by inhibiting orotidylate decarboxylase (uridine 5'-phosphate synthase). Pyrazofurin, also known as 3,b-D-ribofuranosyl-4- hydroxypyrazole-5-carboxamide, is the prodrug of the 5’-phosphate derivative. Target(s): adenosylhomocysteinase; 5-aminoimidazole-4- carboxamide-1-b-D-ribofuranosyl 5'-monophosphate formyltransferase; orotate phosphoribosyltransferase; orotidylate decarboxylase, or UMP synthase.
Pyrazofurin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Pyrazofurin manufacturers
- Product
- Pyrazofurin 30868-30-5
- Price
- US $1.00/Kg
- Min. Order
- 1Kg
- Purity
- 98%
- Supply Ability
- 20T
- Release date
- 2024-07-22