Pyrazole-3-carboxamide

Product Name: Pyrazole-3-carboxamide
CAS No.: 33064-36-7
Chemical Name: Pyrazole-3-carboxamide
Synonyms: Aficamten Impurity 38;Pyrazol-3-carboxamide;Pyrazole-3-carboxamide;1H-Pyrazole-3-carboxamide
CBNumber: CB61504020
Molecular Formula: C4H5N3O
Formula Weight: 111.1
MOL File: 33064-36-7.mol

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Pyrazole-3-carboxamide Property

Melting point:: 159-160 °C
Boiling point:: 469.6±18.0 °C(Predicted)
Density: 1.394
storage temp.: Sealed in dry,Room Temperature
pka: 11.76±0.10(Predicted)
Appearance: White to off-white Solid

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Safety

HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B529885
Product name: 1H-Pyrazole-3-carboxamide
Packaging: 1g
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: W5477
Product name: Pyrazole-3-carboxamide
Packaging: 10g
Price: $214
Updated: 2021/12/16

AK Scientific

Product number: J50581
Product name: Pyrazole-3-carboxamide
Packaging: 25g
Price: $320
Updated: 2021/12/16

Matrix Scientific

Product number: 057796
Product name: 1H-Pyrazole-3-carboxamide
Purity: 98%
Packaging: 5g
Price: $476
Updated: 2021/12/16

AstaTech

Product number: CL3448
Product name: PYRAZOLE-3-CARBOXAMIDE
Purity: 97%
Packaging: 100/ G
Price: $800
Updated: 2021/12/16

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Pyrazole-3-carboxamide Chemical Properties,Usage,Production

Synthesis

2075-46-9

33064-36-7

This Example illustrates the preparation of compound 108, 3-pyridine carboxylic acid, 5-[(4-amino-1H-pyrazol-1-yl)carbonyl]-2-methoxy-4-(2-methylpropyl)-6-(trifluoromethyl)-, methyl ester. A tetrahydrofuran (THF, 100 mL) solution of 4-nitropyrazole (22.62 g, 200 mmol) was cooled to 0 °C, followed by slow dropwise addition of a THF solution of sodium bis(trimethylmethylsilyl)amide (204.3 mmol) at 0 °C. Subsequently, a THF (100 mL) solution of compound 84 (70.75 g, 200 mmol) was added slowly dropwise at 0 °C. After the dropwise addition was completed, the reaction mixture was stirred at 25 °C for 30 min. After completion of the reaction, the mixture was poured into 5% hydrochloric acid solution and extracted with dichloromethane. The organic layer was dried with anhydrous magnesium sulfate (MgSO?) and the solvent was subsequently removed by rotary evaporator. The residue was purified by silica gel column chromatography (eluent: 5% ethyl acetate/hexane) to afford pyrazolamide (compound 101) 70.14 g in 82% yield.

References

[1] Patent: US5125956, 1992, A

Pyrazole-3-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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Pyrazole-3-carboxamide Suppliers

China 90 India 2 United States 6 Global 98

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View Lastest Price from Pyrazole-3-carboxamide manufacturers

Career Henan Chemical Co

Product: Pyrazole-3-carboxamide 33064-36-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1kg-1000kg
Release date: 2020-01-03

33064-36-7, Pyrazole-3-carboxamideRelated Search:

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1H-Pyrazole-3-carboxamide

Pyrazole-3-carboxamide

Pyrazol-3-carboxamide

Aficamten Impurity 38

33064-36-7