Uses
ChemicalBook > CAS DataBase List > Pyrazole-3-carboxamide

Pyrazole-3-carboxamide

Uses
Product Name
Pyrazole-3-carboxamide
CAS No.
33064-36-7
Chemical Name
Pyrazole-3-carboxamide
Synonyms
Aficamten Impurity 38;Pyrazol-3-carboxamide;Pyrazole-3-carboxamide;1H-Pyrazole-3-carboxamide
CBNumber
CB61504020
Molecular Formula
C4H5N3O
Formula Weight
111.1
MOL File
33064-36-7.mol
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Pyrazole-3-carboxamide Property

Melting point:
159-160 °C
Boiling point:
469.6±18.0 °C(Predicted)
Density 
1.394
storage temp. 
Sealed in dry,Room Temperature
pka
11.76±0.10(Predicted)
Appearance
White to off-white Solid
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Safety

HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B529885
Product name
1H-Pyrazole-3-carboxamide
Packaging
1g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
W5477
Product name
Pyrazole-3-carboxamide
Packaging
10g
Price
$214
Updated
2021/12/16
AK Scientific
Product number
J50581
Product name
Pyrazole-3-carboxamide
Packaging
25g
Price
$320
Updated
2021/12/16
Matrix Scientific
Product number
057796
Product name
1H-Pyrazole-3-carboxamide
Purity
98%
Packaging
5g
Price
$476
Updated
2021/12/16
Chemenu
Product number
CM189059
Product name
1H-Pyrazole-3-carboxamide
Purity
95+%
Packaging
5g
Price
$69
Updated
2021/12/16
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Pyrazole-3-carboxamide Chemical Properties,Usage,Production

Uses

Pyrazole-3-carboxamide has a wide range of biological activities and can be used in pharmaceutical and pesticide research.

Synthesis

2075-46-9

33064-36-7

This Example illustrates the preparation of compound 108, 3-pyridine carboxylic acid, 5-[(4-amino-1H-pyrazol-1-yl)carbonyl]-2-methoxy-4-(2-methylpropyl)-6-(trifluoromethyl)-, methyl ester. A tetrahydrofuran (THF, 100 mL) solution of 4-nitropyrazole (22.62 g, 200 mmol) was cooled to 0 °C, followed by slow dropwise addition of a THF solution of sodium bis(trimethylmethylsilyl)amide (204.3 mmol) at 0 °C. Subsequently, a THF (100 mL) solution of compound 84 (70.75 g, 200 mmol) was added slowly dropwise at 0 °C. After the dropwise addition was completed, the reaction mixture was stirred at 25 °C for 30 min. After completion of the reaction, the mixture was poured into 5% hydrochloric acid solution and extracted with dichloromethane. The organic layer was dried with anhydrous magnesium sulfate (MgSO?) and the solvent was subsequently removed by rotary evaporator. The residue was purified by silica gel column chromatography (eluent: 5% ethyl acetate/hexane) to afford pyrazolamide (compound 101) 70.14 g in 82% yield.

References

[1] Patent: US5125956, 1992, A

Pyrazole-3-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Pyrazole-3-carboxamide manufacturers

Career Henan Chemical Co
Product
Pyrazole-3-carboxamide 33064-36-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1kg-1000kg
Release date
2020-01-03

33064-36-7, Pyrazole-3-carboxamideRelated Search:

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  • 1H-Pyrazole-3-carboxamide
  • Pyrazole-3-carboxamide
  • Pyrazol-3-carboxamide
  • Aficamten Impurity 38
  • 33064-36-7