Pyrazole-3-carboxamide
Uses- Product Name
- Pyrazole-3-carboxamide
- CAS No.
- 33064-36-7
- Chemical Name
- Pyrazole-3-carboxamide
- Synonyms
- Aficamten Impurity 38;Pyrazol-3-carboxamide;Pyrazole-3-carboxamide;1H-Pyrazole-3-carboxamide
- CBNumber
- CB61504020
- Molecular Formula
- C4H5N3O
- Formula Weight
- 111.1
- MOL File
- 33064-36-7.mol
Pyrazole-3-carboxamide Property
- Melting point:
- 159-160 °C
- Boiling point:
- 469.6±18.0 °C(Predicted)
- Density
- 1.394
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 11.76±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B529885
- Product name
- 1H-Pyrazole-3-carboxamide
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- W5477
- Product name
- Pyrazole-3-carboxamide
- Packaging
- 10g
- Price
- $214
- Updated
- 2021/12/16
- Product number
- J50581
- Product name
- Pyrazole-3-carboxamide
- Packaging
- 25g
- Price
- $320
- Updated
- 2021/12/16
- Product number
- 057796
- Product name
- 1H-Pyrazole-3-carboxamide
- Purity
- 98%
- Packaging
- 5g
- Price
- $476
- Updated
- 2021/12/16
- Product number
- CM189059
- Product name
- 1H-Pyrazole-3-carboxamide
- Purity
- 95+%
- Packaging
- 5g
- Price
- $69
- Updated
- 2021/12/16
Pyrazole-3-carboxamide Chemical Properties,Usage,Production
Uses
Pyrazole-3-carboxamide has a wide range of biological activities and can be used in pharmaceutical and pesticide research.
Synthesis
2075-46-9
33064-36-7
This Example illustrates the preparation of compound 108, 3-pyridine carboxylic acid, 5-[(4-amino-1H-pyrazol-1-yl)carbonyl]-2-methoxy-4-(2-methylpropyl)-6-(trifluoromethyl)-, methyl ester. A tetrahydrofuran (THF, 100 mL) solution of 4-nitropyrazole (22.62 g, 200 mmol) was cooled to 0 °C, followed by slow dropwise addition of a THF solution of sodium bis(trimethylmethylsilyl)amide (204.3 mmol) at 0 °C. Subsequently, a THF (100 mL) solution of compound 84 (70.75 g, 200 mmol) was added slowly dropwise at 0 °C. After the dropwise addition was completed, the reaction mixture was stirred at 25 °C for 30 min. After completion of the reaction, the mixture was poured into 5% hydrochloric acid solution and extracted with dichloromethane. The organic layer was dried with anhydrous magnesium sulfate (MgSO?) and the solvent was subsequently removed by rotary evaporator. The residue was purified by silica gel column chromatography (eluent: 5% ethyl acetate/hexane) to afford pyrazolamide (compound 101) 70.14 g in 82% yield.
References
[1] Patent: US5125956, 1992, A
Pyrazole-3-carboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
Pyrazole-3-carboxamide Suppliers
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View Lastest Price from Pyrazole-3-carboxamide manufacturers
- Product
- Pyrazole-3-carboxamide 33064-36-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2020-01-03