2H-PYRAZOLE-3-CARBALDEHYDE

Product Name: 2H-PYRAZOLE-3-CARBALDEHYDE
CAS No.: 3920-50-1
Chemical Name: 2H-PYRAZOLE-3-CARBALDEHYDE
Synonyms: 1H-PYRAZOLE-3-CARBALDEHYDE;1H-PYRAZOLE-5-CARBALDEHYDE;Pyrazole-3-carboxaldehyde;DKFELEX0322;3-formylpyrazole;RARECHEM AM LA 0023;PYRAZOLE-3-ALDEHYDE;3-Formyl-1H-pyrazole;Pyrazol-3-carbaldehyde;PYRAZOLE-3-CARBALDEHYDE
CBNumber: CB4670896
Molecular Formula: C4H4N2O
Formula Weight: 96.09
MOL File: 3920-50-1.mol

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2H-PYRAZOLE-3-CARBALDEHYDE Property

Melting point:: 149.0 to 153.0 °C
Boiling point:: 300.0±13.0 °C(Predicted)
Density: 1.323
storage temp.: Inert atmosphere,Room Temperature
form: powder to crystal
pka: 11.20±0.10(Predicted)
color: White to Orange to Green
InChI: InChI=1S/C4H4N2O/c7-3-4-1-2-5-6-4/h1-3H,(H,5,6)
InChIKey: ICFGFAUMBISMLR-UHFFFAOYSA-N
SMILES: N1C=CC(C=O)=N1
CAS DataBase Reference: 3920-50-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-36/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933119000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS009918
Product name: 1<I>H</I>-Pyrazole-3-carbaldehyde
Purity: Aldrich<SUP>CPR</SUP>
Packaging: 50 mg
Price: $107
Updated: 2025/07/31

Sigma-Aldrich

Product number: CDS009918
Product name: 1H-Pyrazole-3-carbaldehyde
Purity: AldrichCPR
Packaging: 50mg
Price: $104
Updated: 2024/03/01

TCI Chemical

Product number: P2261
Product name: Pyrazole-3-carboxaldehyde
Purity: >98.0%(GC)
Packaging: 200mg
Price: $73
Updated: 2025/07/31

TCI Chemical

Product number: P2261
Product name: Pyrazole-3-carboxaldehyde
Purity: >98.0%(GC)
Packaging: 1g
Price: $291
Updated: 2025/07/31

TRC

Product number: P842540
Product name: 1H-Pyrazole-3-carboxaldehyde
Packaging: 1g
Price: $65
Updated: 2021/12/16

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2H-PYRAZOLE-3-CARBALDEHYDE Chemical Properties,Usage,Production

Chemical Properties

Colorless Solid

Uses

1H-?Pyrazole-?3-?carboxaldehyde is an intermediate used to prepare fused pyrrole carboxylic acids as novel, potent D-?amino acid oxidase (DAO) inhibitors. It is also a building block to synthesize α-?substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2?/neu tyrosine kinases.

Synthesis

111573-59-2

3920-50-1

The general procedure for the synthesis of 3-pyrazolecarboxaldehyde from 3-dimethoxymethyl-1H-pyrazole: 2.3 kg of formic acid was added slowly and dropwise to 15.5 kg of an aqueous solution containing 13.8 kg of 3-dimethoxymethyl-1H-pyrazole at 0-15 °C. Subsequently, the reaction mixture was magnetically stirred at 25 °C for 12 h. A light yellow solid was obtained upon completion of the reaction. The precipitate was separated by filtration and the filter cake was washed with 10 L of water to give 643 g of the final yellow solid product 3-pyrazolecarboxaldehyde.

References

[1] Journal of Organic Chemistry, 2007, vol. 72, # 15, p. 5890 - 5893
[2] Chinese Journal of Catalysis, 2016, vol. 37, # 9, p. 1446 - 1450
[3] European Journal of Medicinal Chemistry, 1993, vol. 28, # 2, p. 129 - 140
[4] Patent: CN107235982, 2017, A. Location in patent: Paragraph 0008

2H-PYRAZOLE-3-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2H-PYRAZOLE-3-CARBALDEHYDE Suppliers

Austria 1 Belgium 1 China 214 Europe 1 Germany 3 India 8 Japan 2 Slovakia 2 United Kingdom 9 United States 31 Global 272

Shaanxi Cuikang Pharmaceutical Technology Co., Ltd

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Nanjing Jubai Biomedical Technology Co., Ltd.

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Energy Chemical

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View Lastest Price from 2H-PYRAZOLE-3-CARBALDEHYDE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2H-PYRAZOLE-3-CARBALDEHYDE 3920-50-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-08-15

Jiangsu Magic Biotechnology Co., Ltd

Product: 2H-PYRAZOLE-3-CARBALDEHYDE 3920-50-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2023-05-19

Career Henan Chemical Co

Product: 2H-PYRAZOLE-3-CARBALDEHYDE 3920-50-1
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-19

3920-50-1, 2H-PYRAZOLE-3-CARBALDEHYDERelated Search:

4-Nitropyrazole-3-carboxylic acid 1-(TERT-BUTYL)-3-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID 1-(TERT-BUTYL)-3-METHYL-1H-PYRAZOLE-5-CARBONYL CHLORIDE 5-Methyl-1H-pyrazole-3-carboxylic acid 1-BENZYL-3-(TERT-BUTYL)-1H-PYRAZOLE-5-CARBONYL CHLORIDE Pyrazofurin Ethyl 3-methyl-1H-pyrazole-5-carboxylate ETHYL 1,5-DIMETHYL-1H-PYRAZOLE-3-CARBOXYLATE 1,4-DIHYDRO-3-BETA-D-RIBOFURANOSYL-7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE 3,5-PYRAZOLEDICARBOXYLIC ACID 3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBONYL CHLORIDE 5-Pyrazolecarboxylic acid 5-METHYL-1 H-PYRAZOLE-3-CARBOXYLIC ACID HYDRAZIDE 5-Methyl-1H-pyrazole-4-carbaldehyde 1-PHENYL-1H-PYRAZOLE-5-CARBALDEHYDE 3-CYCLOPROPYL-1-METHYL-1H-PYRAZOLE-4-CARBALDEHYDE 1,5-DIMETHYL-1H-PYRAZOLE-4-CARBALDEHYDE 3-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE

PYRAZOLE-3-CARBALDEHYDE

RARECHEM AM LA 0023

3-formylpyrazole

1H-PYRAZOLE-5-CARBALDEHYDE

1H-PYRAZOLE-3-CARBXALDEHYDE

1H-PYRAZOLE-3-CARBALDEHYDE

2H-PYRAZOLE-3-CARBALDEHYDE

2H-PYRAZOLE-3-CARBOXALDEHYDE

Pyrazole-3-carboxaldehyde

Pyrazol-3-carbaldehyde

1H-Pyrazole-3-carboxaldehyde

3-Pyrazolecarboxaldehyde

1H-Pyrazol-5-carbaldehyde

3-Formyl-1H-pyrazole

1H-Pyrazole-3-carbaldehyde, dimer

1H-Pyrazole-5-carboxaldehyde 97%

Pyrazole-3-carboxaldehyde &gt

1H-PYRAZOLE-3-OARBALDEHYDE

Pyrazole-3-carboxaldehyde (8CI)

1H pyrazole-3-formaldehyde

PYRAZOLE-3-ALDEHYDE

DKFELEX0322

1H-Pyrazole-5-carbaldehyde, 97%

3920-50-1