ChemicalBook > CAS DataBase List > SB9200

SB9200

Product Name: SB9200
CAS No.: 942123-43-5
Chemical Name: SB9200
Synonyms: SB 44;SB9200;GS-9992);Irigivir soproxil;Inarigivir soproxil;SB9200;SB 9200;SB-9200;inarigivir soproxil SB9200;SB9200(Inarigivir soproxil);Inarigivir soproxil, 10 mM in DMSO;Inarigivir soproxil (Synonyms: SB9200
CBNumber: CB73959573
Molecular Formula: C25H34N7O13PS
Formula Weight: 703.62
MOL File: 942123-43-5.mol

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SB9200 Property

Density: 1.80±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 102 mg/mL (144.96 mM)
form: Solid
pka: 9.39±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: I627015
Product name: InarigivirSoproxil
Packaging: 1mg
Price: $275
Updated: 2021/12/16

ChemScene

Product number: CS-0030656
Product name: Inarigivirsoproxil
Purity: 98.16%
Packaging: 5mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0030656
Product name: Inarigivirsoproxil
Purity: 98.16%
Packaging: 10mg
Price: $850
Updated: 2021/12/16

ChemScene

Product number: CS-0030656
Product name: Inarigivirsoproxil
Purity: 98.16%
Packaging: 25mg
Price: $1750
Updated: 2021/12/16

ChemScene

Product number: CS-0030656
Product name: Inarigivirsoproxil
Purity: 98.16%
Packaging: 50mg
Price: $2750
Updated: 2021/12/16

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SB9200 Chemical Properties,Usage,Production

Uses

Inarigivir soproxil, has a broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus and influenza and has demonstrated activity against hepatitis B virus (HBV) in vitro and in vivo.

in vivo

The induction of host immune responses by pretreatment with Inarigivir soproxil (SB 9200) followed by Entecavir (ETV) resulted in antiviral efficacy that was superior to that obtained using the strategy of viral reduction with ETV followed by immunomodulation^[2].
Sequential treatment of chronic WHV carrier woodchucks with Inarigivir soproxil (30 mg/kg)followed by ETV induced marked suppression of serum viremia and antigenemia and delayed recrudescence of viral replication compared to sequential treatment with ETV followed by Inarigivir soproxil^[2].

Animal Model:	Woodchucks chronically infected with woodchuck hepatitis virus (WHV)^[2]
Dosage:	30 mg/kg
Administration:	Orally treated once daily; group 1 received ETV for 4 weeks followed by Inarigivir soproxil for 12 weeks. Group 2 received Inarigivir soproxil for 12 weeks followed by ETV for 4 weeks
Result:	Both groups demonstrated marked reductions in hepatic WHV nucleic acid levels which were more pronounced in Group 2.

SB9200 Preparation Products And Raw materials

Raw materials

Preparation Products

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SB9200 Suppliers

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942123-43-5, SB9200Related Search:

Sb-742457 SBI-0206965 GSK-CXCR2 SBI-993 SB-649868 SB1317 SB 203580 SB 204741 SB1317

SB9200

Inarigivir soproxil

SB9200(Inarigivir soproxil)

SB9200;SB 9200;SB-9200

inarigivir soproxil SB9200

Irigivir soproxil

Adenosine, 2'-O-methyl-P(S)-[[[(1-methylethoxy)carbonyl]oxy]methyl]-P-thiouridylyl-(3'→5')-2'-deoxy-

GS-9992)

Inarigivir soproxil (Synonyms: SB9200

inhibit,Inhibitor,HCV replicon,GS-9992,SB-9200,GS9992,antiviral activity against,HCV,Hepatitis C virus,SB 9200,innate immunity,GS 9992,Inarigivir soproxil,HBV,Hepatitis B virus

(((((2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-yl)oxy)phosphoryl)thio)methyl isopropyl carbonate

SB 44

1-[(2R,3R,4R,5R)-4-[({[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}[({[(propan-2-yloxy)carbonyl]oxy}methyl)sulfanyl]phosphoryl)oxy]-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

Inarigivir soproxil, 10 mM in DMSO

942123-43-5

C25H34N7O13PS