N1-CYCLOPROPYL-2-CHLOROACETAMIDE

Product Name: N1-CYCLOPROPYL-2-CHLOROACETAMIDE
CAS No.: 19047-31-5
Chemical Name: N1-CYCLOPROPYL-2-CHLOROACETAMIDE
Synonyms: AKOS BBS-00006513;AKOS USSH-4110472;OTAVA-BB BB7020410100;2-CHLORO-N-CYCLOPROPYLACETAMIDE;N1-CYCLOPROPYL-2-CHLOROACETAMIDE;Acetamide, 2-chloro-N-cyclopropyl-;2-Chloro-N-cyclopropylacetamide,97%;[N-(cyclopropyl)aminocarbonylmethyl]chloride;2-chloro-N-cyclopropylacetamide(SALTDATA: FREE)
CBNumber: CB7413155
Molecular Formula: C5H8ClNO
Formula Weight: 133.58
MOL File: 19047-31-5.mol

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N1-CYCLOPROPYL-2-CHLOROACETAMIDE Property

Melting point:: 81-84
Boiling point:: 295.8±19.0 °C(Predicted)
Density: 1.21±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 14.08±0.20(Predicted)
Appearance: White to light brown Solid

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Safety

Hazard Codes: Xi
Hazard Note: Harmful
HazardClass: IRRITANT
HS Code: 2924190090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C427778
Product name: 2-Chloro-N-cyclopropylacetamide
Packaging: 25mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 029528
Product name: 2-Chloro-N-cyclopropylacetamide
Packaging: 500mg
Price: $16
Updated: 2021/12/16

Matrix Scientific

Product number: 029528
Product name: 2-Chloro-N-cyclopropylacetamide
Packaging: 1g
Price: $24
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC113978
Product name: 2-Chloro-N-cyclopropylacetamide
Packaging: 250mg
Price: $57.5
Updated: 2021/12/16

ChemScene

Product number: CS-W005640
Product name: 2-Chloro-N-cyclopropylacetamide
Packaging: 5g
Price: $59
Updated: 2021/12/16

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N1-CYCLOPROPYL-2-CHLOROACETAMIDE Chemical Properties,Usage,Production

Synthesis

79-04-9

765-30-0

19047-31-5

To a solution of cyclopropylamine (50.0 g, 0.876 mol) in dichloromethane (700 mL) was added 2-chloroacetyl chloride (49.4 g, 0.436 mol) slowly and dropwise through an addition funnel at 0 °C. The reaction mixture was stirred continuously at 0 °C for 2 h, followed by filtration through a diatomaceous earth pad. The filtrate was concentrated under reduced pressure to give an orange solid. The solid was slurried in 500 mL of hexane and filtered again. The collected orange solid was dried under vacuum at room temperature for 30 min to give the final 2-chloro-N-cyclopropylacetamide (58.12 g, 99% yield). Mass spectrometry analysis (m/z): 134.1 (M++1).

References

[1] Patent: WO2006/47124, 2006, A1. Location in patent: Page/Page column 11-12
[2] Journal of Medicinal Chemistry, 2003, vol. 46, # 3, p. 399 - 408
[3] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 6, p. 678 - 681
[4] Patent: CN106146414, 2016, A. Location in patent: Paragraph 0478; 0479; 0480
[5] ChemMedChem, 2018,

N1-CYCLOPROPYL-2-CHLOROACETAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N1-CYCLOPROPYL-2-CHLOROACETAMIDE Suppliers

Belgium 1 China 60 Germany 1 India 2 Ukraine 3 United Kingdom 3 United States 9 Global 79

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19047-31-5, N1-CYCLOPROPYL-2-CHLOROACETAMIDERelated Search:

2-CHLORO-N-CYCLOPROPYL-N-(4-METHOXYBENZYL)ACETAMIDE 2-CHLORO-N-[[5-(2-CHLOROPHENYL)-1,3,4-OXADIAZOL-2-YL]METHYL]-N-CYCLOPROPYLACETAMIDE 2-CHLORO-N-CYCLOPROPYL-N-(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)ACETAMIDE N1-CYCLOPROPYL-2-CHLOROACETAMIDE 2-CHLORO-N-CYCLOPROPYL-2-PHENYLACETAMIDE 2-chloro-N-cyclopropyl-N-ethylacetamide 2-CHLORO-N-CYCLOPROPYL-N-(2-FLUOROBENZYL)ACETAMIDE 2,2-DICHLORO-N-CYCLOPROPYLACETAMIDE 2-CHLORO-N-(1-CYANO-1-METHYLETHYL)-N-CYCLOPROPYLACETAMIDE 2-CHLORO-N-CYCLOHEX-1-EN-1-YL-N-CYCLOPROPYLACETAMIDE 2-CHLORO-N-CYCLOPROPYLPROPANAMIDE

OTAVA-BB BB7020410100

N1-CYCLOPROPYL-2-CHLOROACETAMIDE

AKOS USSH-4110472

AKOS BBS-00006513

2-CHLORO-N-CYCLOPROPYLACETAMIDE

[N-(cyclopropyl)aminocarbonylmethyl]chloride

2-chloro-N-cyclopropylacetamide(SALTDATA: FREE)

Acetamide, 2-chloro-N-cyclopropyl-

2-Chloro-N-cyclopropylacetamide,97%

19047-31-5

19407-31-5

Amines

Ring Systems