N1-CYCLOPROPYL-2-CHLOROACETAMIDE
- Product Name
- N1-CYCLOPROPYL-2-CHLOROACETAMIDE
- CAS No.
- 19047-31-5
- Chemical Name
- N1-CYCLOPROPYL-2-CHLOROACETAMIDE
- Synonyms
- AKOS BBS-00006513;AKOS USSH-4110472;OTAVA-BB BB7020410100;2-CHLORO-N-CYCLOPROPYLACETAMIDE;N1-CYCLOPROPYL-2-CHLOROACETAMIDE;Acetamide, 2-chloro-N-cyclopropyl-;2-Chloro-N-cyclopropylacetamide,97%;[N-(cyclopropyl)aminocarbonylmethyl]chloride;2-chloro-N-cyclopropylacetamide(SALTDATA: FREE)
- CBNumber
- CB7413155
- Molecular Formula
- C5H8ClNO
- Formula Weight
- 133.58
- MOL File
- 19047-31-5.mol
N1-CYCLOPROPYL-2-CHLOROACETAMIDE Property
- Melting point:
- 81-84
- Boiling point:
- 295.8±19.0 °C(Predicted)
- Density
- 1.21±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 14.08±0.20(Predicted)
- Appearance
- White to light brown Solid
Safety
- Hazard Codes
- Xi
- Hazard Note
- Harmful
- HazardClass
- IRRITANT
- HS Code
- 2924190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C427778
- Product name
- 2-Chloro-N-cyclopropylacetamide
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 029528
- Product name
- 2-Chloro-N-cyclopropylacetamide
- Packaging
- 500mg
- Price
- $16
- Updated
- 2021/12/16
- Product number
- 029528
- Product name
- 2-Chloro-N-cyclopropylacetamide
- Packaging
- 1g
- Price
- $24
- Updated
- 2021/12/16
- Product number
- FC113978
- Product name
- 2-Chloro-N-cyclopropylacetamide
- Packaging
- 250mg
- Price
- $57.5
- Updated
- 2021/12/16
- Product number
- CS-W005640
- Product name
- 2-Chloro-N-cyclopropylacetamide
- Packaging
- 5g
- Price
- $59
- Updated
- 2021/12/16
N1-CYCLOPROPYL-2-CHLOROACETAMIDE Chemical Properties,Usage,Production
Synthesis
79-04-9
765-30-0
19047-31-5
To a solution of cyclopropylamine (50.0 g, 0.876 mol) in dichloromethane (700 mL) was added 2-chloroacetyl chloride (49.4 g, 0.436 mol) slowly and dropwise through an addition funnel at 0 °C. The reaction mixture was stirred continuously at 0 °C for 2 h, followed by filtration through a diatomaceous earth pad. The filtrate was concentrated under reduced pressure to give an orange solid. The solid was slurried in 500 mL of hexane and filtered again. The collected orange solid was dried under vacuum at room temperature for 30 min to give the final 2-chloro-N-cyclopropylacetamide (58.12 g, 99% yield). Mass spectrometry analysis (m/z): 134.1 (M++1).
References
[1] Patent: WO2006/47124, 2006, A1. Location in patent: Page/Page column 11-12
[2] Journal of Medicinal Chemistry, 2003, vol. 46, # 3, p. 399 - 408
[3] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 6, p. 678 - 681
[4] Patent: CN106146414, 2016, A. Location in patent: Paragraph 0478; 0479; 0480
[5] ChemMedChem, 2018,
N1-CYCLOPROPYL-2-CHLOROACETAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
N1-CYCLOPROPYL-2-CHLOROACETAMIDE Suppliers
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