3-(DIMETHYLAMINO)-1-PHENYL-2-PROPEN-1-ONE
- Product Name
- 3-(DIMETHYLAMINO)-1-PHENYL-2-PROPEN-1-ONE
- CAS No.
- 1201-93-0
- Chemical Name
- 3-(DIMETHYLAMINO)-1-PHENYL-2-PROPEN-1-ONE
- Synonyms
- NSC 601833;3-(Dimethylamino)acrylophenone;3-(Dimethylamino)phenylpropenone;3-Dimethylamino-1-phenylpropenone;3-(Dimethylamino)-1-phenylprop-2-en-1-one;3-(DIMETHYLAMINO)-1-PHENYL-2-PROPEN-1-ONE;2-Propen-1-one, 3-(dimethylamino)-1-phenyl-;3-(N,N-Dimethylamino)-1-phenyl-2-propen-1-one;(2E)-3-(Dimethylamino)-1-phenylprop-2-en-1-one;3 - (dimethylamino) - 1 - (2-phenyl) - 2-propene-1-one
- CBNumber
- CB7425011
- Molecular Formula
- C11H13NO
- Formula Weight
- 175.23
- MOL File
- 1201-93-0.mol
3-(DIMETHYLAMINO)-1-PHENYL-2-PROPEN-1-ONE Property
- Melting point:
- 91-93°C
- Boiling point:
- 260.0±32.0 °C(Predicted)
- Density
- 1.022±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 6.63±0.70(Predicted)
- color
- White to Yellow to Green
- λmax
- 325nm(lit.)
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2922390090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H228Flammable solid
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378In case of fire: Use … for extinction.
N-Bromosuccinimide Price
- Product number
- S447862
- Product name
- 3-DIMETHYLAMINO-1-PHENYL-2-PROPEN-1-ONE
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $185
- Updated
- 2025/07/31
- Product number
- S447862
- Product name
- 3-DIMETHYLAMINO-1-PHENYL-2-PROPEN-1-ONE
- Purity
- AldrichCPR
- Packaging
- 1G
- Price
- $179
- Updated
- 2024/03/01
- Product number
- D5384
- Product name
- 3-(Dimethylamino)-1-phenyl-2-propen-1-one
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $65
- Updated
- 2025/07/31
- Product number
- D5384
- Product name
- 3-(Dimethylamino)-1-phenyl-2-propen-1-one
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $197
- Updated
- 2025/07/31
- Product number
- D492935
- Product name
- 3-Dimethylamino-1-phenyl-2-propen-1-one
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
3-(DIMETHYLAMINO)-1-PHENYL-2-PROPEN-1-ONE Chemical Properties,Usage,Production
Definition
ChEBI: 3-(dimethylamino)-1-phenylprop-2-en-1-one is a carbonyl compound.
Synthesis Reference(s)
Chemistry Letters, 13, p. 1419, 1984
The Journal of Organic Chemistry, 45, p. 4522, 1980 DOI: 10.1021/jo01310a058
Synthesis
4637-24-5
98-86-2
1201-93-0
In a 100 mL dry round-bottomed flask, acetophenone (1.08 g, 9 mmol) and N,N-dimethylformamide dimethyl acetal (3.9 mL, 30 mmol) were added with 30 mL of xylene as solvent. The reaction mixture was refluxed at 140 °C for 12 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) and the heating was stopped after confirming the completion of the reaction. The solvent was removed by distillation under reduced pressure and the resulting crude product was purified by fast column chromatography to afford 3-(dimethylamino)-1-phenyl-2-propen-1-one (1.48 g, 97% yield) as a light yellow solid.
References
[1] RSC Advances, 2017, vol. 7, # 45, p. 28483 - 28488
[2] Patent: CN108383763, 2018, A. Location in patent: Paragraph 0044; 0046
[3] Patent: US2011/195993, 2011, A1. Location in patent: Page/Page column 10; 14
[4] Journal of Organic Chemistry, 1980, vol. 45, # 24, p. 4857 - 4860
[5] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 4, p. 1214 - 1217
3-(DIMETHYLAMINO)-1-PHENYL-2-PROPEN-1-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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