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Sodium glucoheptonate

Background
Product Name
Sodium glucoheptonate
CAS No.
31138-65-5
Chemical Name
Sodium glucoheptonate
Synonyms
SODIUM HEPTAGLUCONATE;Sodium Glucoheptonate Dihydrate;GAL[2346AC]Β(1-3)GLCN3[46BZD]-Β-MP;Squalane 111-01-3;LacMP 4'-OH, per OBn;LacMP 3'-OH, per OBn;Natriumglucoheptonat;SODIUM GLUCOHEPTONATE;SODIUM GLUCO HEPTANATE;SODIUM A-GLUCOHEPTONATE
CBNumber
CB7430675
Molecular Formula
C7H15NaO8
Formula Weight
250.18
MOL File
31138-65-5.mol
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Sodium glucoheptonate Property

Melting point:
177 °C
Boiling point:
117℃[at 101 325 Pa]
Density 
1.45[at 20℃]
refractive index 
132.5 ° (C=1, H2O)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO: 50 mg/mL (175.94 mM);Ethanol: Insoluble
form 
Powder
color 
White
Water Solubility 
Freely soluble in water
InChI
InChI=1/C7H14O8.Na.H/c8-1-2(9)3(10)4(11)5(12)6(13)7(14)15;;/h2-6,8-13H,1H2,(H,14,15);;/t2-,3-,4+,5-,6?;;/s3
InChIKey
STSMDPCOZSWONE-SCJDZOBNNA-N
SMILES
[C@H](O)([C@H](O)[C@H](O)CO)[C@@H](O)C(O)C(=O)O.[NaH] |&1:0,2,4,8,r|
LogP
-6.44 at 20℃
CAS DataBase Reference
31138-65-5(CAS DataBase Reference)
EPA Substance Registry System
D-gluco-Heptonic acid, monosodium salt, (2.xi.)- (31138-65-5)
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Safety

Safety Statements 
24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
2918.19.9000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

TCI Chemical
Product number
G0330
Product name
Gal[2346Ac]β(1-3)GalN3[46Bzd]-β-MP
Packaging
1G
Price
$375
Updated
2025/07/31
TCI Chemical
Product number
M1763
Product name
Neu5GcAc[1Me,4789Ac]α(2-6)Gal[24Bz,3Bn]-β-MP
Packaging
200MG
Price
$773
Updated
2025/07/31
TCI Chemical
Product number
G0330
Product name
Gal[2346Ac]β(1-3)GalN3[46Bzd]-β-MP
Packaging
5G
Price
$1229
Updated
2025/07/31
TCI Chemical
Product number
G0311
Product name
Gal[2346Ac]β(1-3)GlcNPhth[46Bzd]-β-MP
Packaging
1G
Price
$185
Updated
2025/07/31
TCI Chemical
Product number
G0311
Product name
Gal[2346Ac]β(1-3)GlcNPhth[46Bzd]-β-MP
Packaging
5G
Price
$555
Updated
2025/07/31
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Sodium glucoheptonate Chemical Properties,Usage,Production

Background

The value of the sugar acids and their soluble salts and lactones as sequestering or chelating agents for metal ions, particularly in alkaline solutions, has been recognized for many years. These materials have been used industrially in alkaline de-rusting processes, bottle washing, descaling, for the prevention of iron-staining in paper making, and in the processing of cotton and other textiles, among numerous other applications which could be mentioned. Soil gluconates, particularly sodium gluconate, have become the most widespread use for these purposes, primarily because of their availability and relatively low cost. Kiliani prepared sodium glucoheptonate as early as 1886 by the reaction of hydrocyanic acid with glucose in an aqueous solution, and many modified methods for the preparation of the valuable salt have been suggested. However, it is available only in highly coloured amber to red or red-brown solutions. Such highly colored sequestering agents are unsuitable in many applications in the paper, textile and pharmaceutical industries.

Uses

Sodium glucoheptonate is used for cleaning metal, mercerizing, paint stripping, and aluminum etching. It is also used to mercerize cotton, linen, hemp, and other plant-based fibers to increase strength and add luster to their overall appearance of threads and fabrics.

Synthesis

98 g (2 mol) of sodium cyanide and 300 g of water were charged into a flask fitted with a stirrer, thermometer and a connection to a water jet aspirator. The contents of the flask were cooled to 2 ℃. using an ice bath. 396 g (2 mol) of dextrose hydrate were charged into the flask over about 30 minutes. When the sugar had all been charged, the temperature rose to 8 ℃., when the vacuum jet was turned on to provide a vacuum of about 40 mm of Hg. Within about 30 minutes, the temperature rose to 27 ℃., when the ammonia began to boil off vigorously. Within approximately 1 hour, the alpha sodium glucoheptonate dihydrate began to crystallize. The removal of the ammonia was continued at 27 ℃ and a vacuum of 33-40 mm of Hg for 6 hours. The crystals were filtered, water washed, and air dried. The first crop yield of alpha sodium glucoheptonate was -328 grams or 57.7% of the theoretical.

in vivo

Tc-99m glucoheptonate exhibits rapid blood clearance and quite stable blood level[2].

Toxics Screening Level

The initial threshold screening level (ITSL) for sodium glucoheptonate is 0.1μg/m3 based on an annual averaging time.

Sodium glucoheptonate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Sodium glucoheptonate manufacturers

Hebei Yiduo Import and Export Co., Ltd.
Product
Sodium glucoheptonate 31138-65-5
Price
US $100.00-80.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000000
Release date
2025-07-15
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Sodium glucoheptonate 31138-65-5
Price
US $0.00/G
Min. Order
10G
Purity
98%min
Supply Ability
30kg/month
Release date
2023-02-13
Hebei Chuanghai Biotechnology Co., Ltd
Product
SODIUM GLUCOHEPTONATE 31138-65-5
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100
Release date
2024-10-24

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