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VOACANGINE

Product Name
VOACANGINE
CAS No.
510-22-5
Chemical Name
VOACANGINE
Synonyms
VOACANGINE;(-)-Voacangine;Carbomethoxyibogaine;12-Methoxyibogamine-18-carboxylic acid methyl ester;Ibogamine-18-carboxylic acid, 12-methoxy-, methyl ester
CBNumber
CB7433742
Molecular Formula
C22H28N2O3
Formula Weight
368.47
MOL File
510-22-5.mol
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VOACANGINE Property

Melting point:
223-224℃ (dec.)
Density 
1.25±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
Store at -20°C,protect from light
solubility 
DMF: 16 mg/ml; DMSO: 16 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.33 mg/ml
form 
A crystalline solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
24692
Product name
Voacangine
Purity
≥98%
Packaging
1mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
24692
Product name
Voacangine
Purity
≥98%
Packaging
5mg
Price
$356
Updated
2024/03/01
Cayman Chemical
Product number
24692
Product name
Voacangine
Purity
≥98%
Packaging
10mg
Price
$632
Updated
2024/03/01
TRC
Product number
V757300
Product name
(-)-Voacangine
Packaging
25mg
Price
$695
Updated
2021/12/16
TRC
Product number
V757300
Product name
(-)-Voacangine
Packaging
50mg
Price
$1200
Updated
2021/12/16
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VOACANGINE Chemical Properties,Usage,Production

Description

This alkaloid is of widespread occurrence, being found in Stemmadenia species and also is Vocanga africana, v. dregii and V. obtusa. It forms colourless needles when crystallized from MeOH and has [0'10 - 42° (c 1.0, CHCI3). It sublimes under vacuum at 135°CjO.01 mm and is readily soluble in CHC13 or Me2CO, but only sparingly so in EtOH or MeOH. Hydrolysis with KOH followed by acidification with HCl yields Ibogaine (q.v.).

Uses

(-)-Voacangine is a bisindole alkaloid with ether-?a-?go-?go-?related gene channel blocker activity in vitro. hERG channel blocker.

Definition

ChEBI: (-)-voacangine is a monoterpenoid indole alkaloid with formula C22H28N2O3, isolated from several plant species. It has a role as an angiogenesis inhibitor, an antineoplastic agent and a plant metabolite. It is a monoterpenoid indole alkaloid, a tertiary amino compound, a methyl ester, an organic heteropentacyclic compound and an alkaloid ester. It is a conjugate base of a (-)-voacangine(1+).

References

lanot, Goutarel., Compt. rend., 241,986 (1955) Stauffacher, Seebeck., Helv. Chim. Acta, 41,169 (1958) Watts, Collera, Sandoval., Tetrahedron, 2, 173 (1958) Schuler, Verbeck, Warren.,J. Chern. Soc., 4776 (1958) Bartlett, Dickel, Taylor.,J. Amer. Chern. Soc., 80, 126 (1958) Renner, Prins, Stoll., Helv. Chim. Acta, 42,1572 (1959) Budzikiewicz etal., Bull. Soc. Chim. Fr., 1899 (1963)

VOACANGINE Preparation Products And Raw materials

Raw materials

Preparation Products

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VOACANGINE Suppliers

BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
ALB Technology Limited
Tel
702-983-3769
Fax
702-983-3769
Email
sales@albtechnology.com
Country
United States
ProdList
2993
Advantage
55
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7057
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Shanghai ChengShao Biological Technology Co., Ltd.
Tel
021-61847300 13341622919
Fax
021-61847300
Email
shcss01@163.com
Country
China
ProdList
4808
Advantage
58
JinJin Le Chemical Co., Ltd
Tel
10106090
Email
jjlchem2@163.com
Country
China
ProdList
9981
Advantage
58
Hebei Yanxi Chemical Co., Ltd.
Tel
+8617531190177
Email
peter@yan-xi.com
Country
China
ProdList
5857
Advantage
58
Zhejiang Lianshuo Biotechnology Co., Ltd.
Tel
18616526224
Email
lianshuo@vip.126.com
Country
China
ProdList
9607
Advantage
58
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View Lastest Price from VOACANGINE manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
Voacangine 510-22-5
Price
US $50.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2023-09-08
Hebei Kangcang new material Technology Co., LTD
Product
Voacangine 510-22-5
Price
US $9.00-70.00/g
Min. Order
10g
Purity
99%
Supply Ability
10 tons
Release date
2024-03-27