VOACANGINE

Product Name: VOACANGINE
CAS No.: 510-22-5
Chemical Name: VOACANGINE
Synonyms: VOACANGINE;(-)-Voacangine;Carbomethoxyibogaine;12-Methoxyibogamine-18-carboxylic acid methyl ester;Ibogamine-18-carboxylic acid, 12-methoxy-, methyl ester
CBNumber: CB7433742
Molecular Formula: C22H28N2O3
Formula Weight: 368.47
MOL File: 510-22-5.mol

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VOACANGINE Property

Melting point:: 223-224℃ (dec.)
Density: 1.25±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.: Store at -20°C,protect from light
solubility: DMF: 16 mg/ml; DMSO: 16 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.33 mg/ml
form: A crystalline solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 24692
Product name: Voacangine
Purity: ≥98%
Packaging: 1mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 24692
Product name: Voacangine
Purity: ≥98%
Packaging: 5mg
Price: $356
Updated: 2024/03/01

Cayman Chemical

Product number: 24692
Product name: Voacangine
Purity: ≥98%
Packaging: 10mg
Price: $632
Updated: 2024/03/01

TRC

Product number: V757300
Product name: (-)-Voacangine
Packaging: 25mg
Price: $695
Updated: 2021/12/16

TRC

Product number: V757300
Product name: (-)-Voacangine
Packaging: 50mg
Price: $1200
Updated: 2021/12/16

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VOACANGINE Chemical Properties,Usage,Production

Description

This alkaloid is of widespread occurrence, being found in Stemmadenia species and also is Vocanga africana, v. dregii and V. obtusa. It forms colourless needles when crystallized from MeOH and has [0'10 - 42° (c 1.0, CHCI3). It sublimes under vacuum at 135°CjO.01 mm and is readily soluble in CHC13 or Me2CO, but only sparingly so in EtOH or MeOH. Hydrolysis with KOH followed by acidification with HCl yields Ibogaine (q.v.).

Uses

(-)-Voacangine is a bisindole alkaloid with ether-?a-?go-?go-?related gene channel blocker activity in vitro. hERG channel blocker.

Definition

ChEBI: (-)-voacangine is a monoterpenoid indole alkaloid with formula C22H28N2O3, isolated from several plant species. It has a role as an angiogenesis inhibitor, an antineoplastic agent and a plant metabolite. It is a monoterpenoid indole alkaloid, a tertiary amino compound, a methyl ester, an organic heteropentacyclic compound and an alkaloid ester. It is a conjugate base of a (-)-voacangine(1+).

References

lanot, Goutarel., Compt. rend., 241,986 (1955) Stauffacher, Seebeck., Helv. Chim. Acta, 41,169 (1958) Watts, Collera, Sandoval., Tetrahedron, 2, 173 (1958) Schuler, Verbeck, Warren.,J. Chern. Soc., 4776 (1958) Bartlett, Dickel, Taylor.,J. Amer. Chern. Soc., 80, 126 (1958) Renner, Prins, Stoll., Helv. Chim. Acta, 42,1572 (1959) Budzikiewicz etal., Bull. Soc. Chim. Fr., 1899 (1963)

VOACANGINE Preparation Products And Raw materials

Raw materials

Preparation Products

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VOACANGINE Suppliers

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View Lastest Price from VOACANGINE manufacturers

Hebei Kangcang new material Technology Co., LTD

Product: Voacangine 510-22-5
Price: US $9.00-70.00/g
Min. Order: 10g
Purity: 99%
Supply Ability: 10 tons
Release date: 2024-03-27

Hebei Yanxi Chemical Co., Ltd.

Product: Voacangine 510-22-5
Price: US $50.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10000
Release date: 2023-09-08

510-22-5, VOACANGINERelated Search:

3-(2-methylaminoethyl)-1H-indol-5-ol N,N-Dimethyl-5-methoxytryptamine 2-TERT-BUTYL-1H-INDOLE 3,5-Dimethylpiperidine METHYL BETA-(DIMETHYLAMINO)ISOBUTYRATE Methyl piperidine-3-carboxylate (R)-Methyl nipecotate 2-Piperidineethanol Bufotenine 1-METHYL-1-CYCLOHEXANECARBOXYLIC ACID N,N-DIPROPYLTRYPTAMINE INDOLE-2-ACETIC ACID CHEMBRDG-BB 5569568 5-METHOXY-N,N-DIETHYLTRYPTAMINE(5-MEO-DET) VOACANGINE 2,6-DIMETHYLCYCLOHEXYLAMINE 3-AMINO-HEPTANOIC ACID 5-Methoxy-N,N-dipropyltryptamine

VOACANGINE

12-Methoxyibogamine-18-carboxylic acid methyl ester

Carbomethoxyibogaine

Ibogamine-18-carboxylic acid, 12-methoxy-, methyl ester

(-)-Voacangine

510-22-5