NERYLACETONE Property

Boiling point:

250-255 °C

Density 

0.868 g/mL at 20 °C(lit.)

refractive index 

n20/D 1.467

storage temp. 

2-8°C

Odor

at 100.00 %. fatty metallic

Odor Type

fatty

LogP

4.129 (est)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

NERYLACETONE Chemical Properties,Usage,Production

Uses

Nerylacetone is an intermediate in the synthesis of cis-Nerolidol (N390125), one of the main component in the essential oils from fresh aerial parts of Thymus ciliatus (Lamiaceae). Also, it is a terpene that displays high potency on the contractility of cardiac muscle in guinea pig left atrium. A potential and effective treatment for malaria.

Synthesis Reference(s)

Journal of the American Chemical Society, 97, p. 6870, 1975 DOI: 10.1021/ja00856a049
The Journal of Organic Chemistry, 38, p. 4082, 1973 DOI: 10.1021/jo00987a035