ChemicalBook > CAS DataBase List > 2-Bromomalonaldehyde

2-Bromomalonaldehyde

Product Name
2-Bromomalonaldehyde
CAS No.
2065-75-0
Chemical Name
2-Bromomalonaldehyde
Synonyms
BROMOMALONALDEHYDE;Bromomalonaldehyde 97%;onaL;BromomaL;2-Bromomaloldehyde;2-BROMOMALONALDEHYDE;Propanedial, 2-broMo-;2-bromomalondialdehyde;2-broMo-1,3-propanedial;2-Bromomalonaldehyde ,99%
CBNumber
CB7453102
Molecular Formula
C3H3BrO2
Formula Weight
150.96
MOL File
2065-75-0.mol
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2-Bromomalonaldehyde Property

Melting point:
132-136 °C(lit.)
Boiling point:
134.8±25.0 °C(Predicted)
Density 
1.750±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Acetonitrile (Slightly), DMSO (Slightly)
form 
Solid
pka
1.70±0.10(Predicted)
color 
Pale Beige to Pale Yellow
Sensitive 
Air Sensitive
InChI
InChI=1S/C3H3BrO2/c4-3(1-5)2-6/h1-3H
InChIKey
SURMYNZXHKLDFO-UHFFFAOYSA-N
SMILES
C(=O)C(Br)C=O
CAS DataBase Reference
2065-75-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant/Keep Cold
HS Code 
29130000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
535079
Product name
Bromomalonaldehyde
Purity
97%
Packaging
5g
Price
$124
Updated
2025/07/31
Sigma-Aldrich
Product number
535079
Product name
Bromomalonaldehyde
Purity
97%
Packaging
25g
Price
$268
Updated
2025/07/31
TCI Chemical
Product number
B3699
Product name
Bromomalonaldehyde
Purity
min. 95.0 %
Packaging
25G
Price
$54
Updated
2025/07/31
TRC
Product number
B684490
Product name
Bromomalonaldehyde
Packaging
50g
Price
$120
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK180445
Product name
2-Bromomalonaldehyde
Purity
99%
Packaging
5g
Price
$128
Updated
2021/12/16
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2-Bromomalonaldehyde Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Solid

Uses

Used in the formation of glyoxal-derived adducts from substituted guanines

Synthesis

102-52-3

2065-75-0

1,1,3,3-tetramethoxypropane (23) (10 g) was used as a raw material, and a solution of water (H2O, 11 mL) with concentrated HCl (0.43 mL) was stirred at room temperature for 10 minutes. Subsequently, Br2 (3.1 mL) was slowly added dropwise to the above solution at room temperature for a controlled time of 50 minutes or more. After the dropwise addition was completed, the reaction mixture was continued to be stirred at room temperature for 20 minutes. After completion of the reaction, the mixture was concentrated under vacuum. The resulting residual solid was washed with water (H2O) to give the final target product 2-bromomalonaldehyde (24) (3.6 g, 39%) as a yellow solid. The melting point of the product was 147-148 °C; 1H NMR (CDCl3) δ 4.73-4.80 (1H,m),8.47 (2H,br s); FAB MS m/e (M-H)-149.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 1, p. 235 - 238
[2] Patent: US2005/85492, 2005, A1. Location in patent: Page/Page column 25
[3] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 5, p. 1219 - 1233
[4] Organic and Biomolecular Chemistry, 2005, vol. 3, # 18, p. 3388 - 3398
[5] Patent: WO2004/67521, 2004, A1. Location in patent: Page 68

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View Lastest Price from 2-Bromomalonaldehyde manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Bromomalonaldehyde 2065-75-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-11-14
Zibo Hangyu Biotechnology Development Co., Ltd
Product
2-Bromomalonaldehyde 2065-75-0
Price
US $70.00-700.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-08
R&D Scientific Inc.
Product
2-bromomalonaldehyde 2065-75-0
Price
US $350.00/Kg
Min. Order
1Kg
Purity
96
Supply Ability
500 Kg
Release date
2024-07-26

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