Uses
ChemicalBook > CAS DataBase List > TH1020

TH1020

Uses
Product Name
TH1020
CAS No.
1841460-82-9
Chemical Name
TH1020
Synonyms
TH1020;TH1020 >=95% (HPLC);4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2';4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2';4-((4-Benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine;4-((4-Benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine;4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2':4,5]thieno[3,2-d]pyrimidine;Pyrido[3',2':4,5]thieno[3,2-d]pyrimidine, 4-[[4-(phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-;interaction,inhibit,Bacterial,flagellin,TH-1020,TH1020,Toll-like Receptor (TLR),TLR5,protein-protein,TNF-α,Inhibitor,TH 1020;6-{[4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-8-thia-3,5,10-triazatricyclo[7.4.0.02,?]trideca-1(9),2(7),3,5,10,12-hexaene
CBNumber
CB74670635
Molecular Formula
C23H15N7S2
Formula Weight
453.54
MOL File
1841460-82-9.mol
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TH1020 Property

Boiling point:
765.8±70.0 °C(Predicted)
Density 
1.51±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform: 1 mg/ml
form 
powder
pka
1.92±0.10(Predicted)
color 
white to beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1741
Product name
TH1020
Purity
≥95% (HPLC)
Packaging
5MG
Price
$107
Updated
2023/06/20
Sigma-Aldrich
Product number
SML1741
Product name
TH1020
Purity
≥95% (HPLC)
Packaging
25MG
Price
$434
Updated
2023/06/20
Tocris
Product number
6191
Product name
TH1020
Purity
≥98%(HPLC)
Packaging
10
Price
$132
Updated
2021/12/16
Tocris
Product number
6191
Product name
TH1020
Purity
≥98%(HPLC)
Packaging
50
Price
$552
Updated
2021/12/16
TRC
Product number
T430010
Product name
TH1020
Packaging
50mg
Price
$525
Updated
2021/12/16
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TH1020 Chemical Properties,Usage,Production

Uses

TH 1020 is a toll-like receptor 5 (TLR5)/flagellin complex inhibitor.

Uses

TH1020 has been used to inhibit toll-like receptor 5 (TLR5) in porcine intestinal epithelial monolayer cells and mice.

Biochem/physiol Actions

TH1020 is a non-cytotoxic non-cytotoxic toll-like receptor 5 (TLR5)/flagellin complex inhibitor. TH1020 selectively prevents flagellin-induced TLR5 signaling without affecting ligands-induced activation of TLR2, TLR3, TLR4, TLR7 or TLR8.

storage

Store at +4°C

TH1020 Preparation Products And Raw materials

Raw materials

Preparation Products

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TH1020 Suppliers

BOC Sciences
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1-631-485-4226; 16314854226
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info@bocsci.com
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United States
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TargetMol Chemicals Inc.
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+1-781-999-5354 +1-00000000000
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marketing@targetmol.com
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Aladdin Scientific
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+1-+1(833)-552-7181
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sales@aladdinsci.com
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TargetMol Chemicals Inc.
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Email
support@targetmol.com
Country
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ProdList
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Cayman Chemical Company
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United States
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MedChemExpress
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1841460-82-9, TH1020Related Search:


  • TH1020
  • 4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2':4,5]thieno[3,2-d]pyrimidine
  • 4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2'
  • TH1020 >=95% (HPLC)
  • 4-((4-Benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine
  • interaction,inhibit,Bacterial,flagellin,TH-1020,TH1020,Toll-like Receptor (TLR),TLR5,protein-protein,TNF-α,Inhibitor,TH 1020
  • Pyrido[3',2':4,5]thieno[3,2-d]pyrimidine, 4-[[4-(phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-
  • 4-((4-Benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine
  • 6-{[4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-8-thia-3,5,10-triazatricyclo[7.4.0.02,?]trideca-1(9),2(7),3,5,10,12-hexaene
  • 4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2'
  • 1841460-82-9