ChemicalBook > CAS DataBase List > 5'(R)-C-Methyl-2-thiouridine
5'(R)-C-Methyl-2-thiouridine
- Product Name
- 5'(R)-C-Methyl-2-thiouridine
- CAS No.
- 2305416-01-5
- Chemical Name
- 5'(R)-C-Methyl-2-thiouridine
- Synonyms
- 5’(R)-C-Methyl-2-thiouridine;5'(R)-C-Methyl-2-thiouridine;1-((2R,3R,4S,5R)-3,4-dihydroxy-5-((R)-1-hydroxyethyl)tetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
- CBNumber
- CB74672457
- Molecular Formula
- C10H14N2O5S
- Formula Weight
- 274.29
- MOL File
- Mol file
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5'(R)-C-Methyl-2-thiouridine Property
- Density
- 1.63±0.1 g/cm3(Predicted)
- pka
- 7.01±0.20(Predicted)
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5'(R)-C-Methyl-2-thiouridine Chemical Properties,Usage,Production
Uses
5’(R)-C-Methyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
5'(R)-C-Methyl-2-thiouridine Preparation Products And Raw materials
Raw materials
Preparation Products
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