ChemicalBook > CAS DataBase List > 6-AMINO-2H-1,4-BENZOXAZIN-3(4H)-ONE

6-AMINO-2H-1,4-BENZOXAZIN-3(4H)-ONE

Product Name
6-AMINO-2H-1,4-BENZOXAZIN-3(4H)-ONE
CAS No.
89976-75-0
Chemical Name
6-AMINO-2H-1,4-BENZOXAZIN-3(4H)-ONE
Synonyms
Barbituric Acid Impurity 18;6-amino-4H-1,4-benzoxazin-3-one;6-Amino-2H-1,4-benzoxin-3(4H)-one;6-AMINO-4H-BENZO[1,4]OXAZIN-3-ONE;6-AMINO-2H-1,4-BENZOXAZIN-3(4H)-ONE;2H-1,4-benzoxazin-3(4H)-one, 6-amino-;6-Amino-2H-1,4-benzoxazin-3(4H)-one 97%;6-amino-2,4-dihydro-1,4-benzoxazin-3-one;6-Amino-3-oxo-3,4-dihydrobenzo[1,4]oxazine;6-AMino-3,4-dihydro-2H-1,4-benzoxazin-3-one
CBNumber
CB7484481
Molecular Formula
C8H8N2O2
Formula Weight
164.16
MOL File
89976-75-0.mol
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6-AMINO-2H-1,4-BENZOXAZIN-3(4H)-ONE Property

Melting point:
266-268°C
Density 
1.344
storage temp. 
2-8°C
form 
solid
color 
Pale brown
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-52-22
Safety Statements 
26-36/37/39-24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
746037
Product name
6-Amino-2H-1,4-benzoxazin-3(4H)-one
Purity
97%
Packaging
1g
Price
$47.66
Updated
2025/07/31
TRC
Product number
A597095
Product name
6-amino-2,4-dihydro-1,4-benzoxazin-3-one
Packaging
500mg
Price
$215
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA51273
Product name
6-Amino-2H-1,4-Benzoxazin-3(4H)-One
Packaging
2g
Price
$216
Updated
2021/12/16
Matrix Scientific
Product number
043926
Product name
6-Amino-2H-1,4-benzoxazin-3(4H)-one
Purity
>95%
Packaging
5g
Price
$227
Updated
2021/12/16
SynQuest Laboratories
Product number
4H48-1-EQ
Product name
6-Amino-2H-1,4-benzoxazin-3(4H)-one
Packaging
5G
Price
$250
Updated
2021/12/16
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6-AMINO-2H-1,4-BENZOXAZIN-3(4H)-ONE Chemical Properties,Usage,Production

Synthesis

81721-87-1

89976-75-0

General procedure for the synthesis of 6-amino-2H-1,4-benzomorpholin-3(4H)-one from 6-nitro-2H-1,4-benzoxazin-3(4H)-one: to a solution of 6-nitro-2H-1,4-benzoxazin-3(4H)-one (2.97 g, 15.00 mmol) in methanol (50 mL) was added 10% palladium/carbon catalyst (0.30 g). The reaction mixture was stirred under hydrogen atmosphere for 16 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to afford 6-amino-2H-1,4-benzomorpholin-3(4H)-one (2.36 g, 95% yield) as a brown solid. Mass spectrometry (MS) analysis showed a molecular ion peak of 165 (M + H).

References

[1] ChemCatChem, 2014, vol. 6, # 11, p. 3153 - 3159
[2] Patent: WO2018/19252, 2018, A1. Location in patent: Page/Page column 37
[3] ChemSusChem, 2017, vol. 10, # 15, p. 3035 - 3039
[4] Journal of Medicinal Chemistry, 2005, vol. 48, # 1, p. 71 - 90
[5] Patent: US2009/298819, 2009, A1. Location in patent: Page/Page column 16; 22

6-AMINO-2H-1,4-BENZOXAZIN-3(4H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-AMINO-2H-1,4-BENZOXAZIN-3(4H)-ONE Suppliers

China 59 Germany 2 India 3 Ukraine 2 United Kingdom 4 United States 11 Global 81
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
Shanghai Synthfine Chemical Co.,Ltd
Tel
15921303235
Fax
QQ489466966
Email
sales@synthfine.com
Country
China
ProdList
1042
Advantage
58
NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
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58
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60

89976-75-0, 6-AMINO-2H-1,4-BENZOXAZIN-3(4H)-ONERelated Search:

FLUMIOXAZIN Benzomorpholine 6-AMINO-2-METHYL-2H-1,4-BENZOXAZIN-3(4H)-ONE 6-AMINO-4-METHYL-2H-1,4-BENZOXAZIN-3(4H)-ONE 7-AMINO-2H-1,4-BENZOXAZIN-3(4H)-ONE 5-AMINO-2H-1,4-BENZOXAZIN-3(4H)-ONE 8-Amino-2H-1,4-benzoxazin-3(4H)-one 6-Amino-4-propyl-2H-1,4-benzoxazin-3(4H)-one 2-([(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-YL)AMINO]CARBONYL)BENZENECARBOXYLIC ACID 2-(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-YL)-1H-ISOINDOLE-1,3(2H)-DIONE 4-METHYL-6-NITRO-2H-1,4-BENZOXAZIN-3(4H)-ONE N-(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-YL)-4-MORPHOLINECARBOXAMIDE 5-OXO-5-[(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-YL)AMINO]PENTANOIC ACID 1-(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-YL)-1H-PYRROLE-2,5-DIONE 6-(1H-PYRROL-1-YL)-2H-1,4-BENZOXAZIN-3(4H)-ONE N,N-DIBENZYL-N'-(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-YL)UREA 4-(4-FLUOROPHENYL)-N-(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-YL)TETRAHYDRO-1(2H)-PYRAZINECARBOXAMIDE (E)-4-OXO-4-[(3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-YL)AMINO]-2-BUTENOIC ACID

  • 6-AMINO-4H-BENZO[1,4]OXAZIN-3-ONE
  • 6-AMINO-2H-1,4-BENZOXAZIN-3(4H)-ONE
  • 2H-1,4-benzoxazin-3(4H)-one, 6-amino-
  • 6-Amino-2H-1,4-benzoxin-3(4H)-one
  • 6-amino-2H-1,4-benzoxazin-3(4H)-one(SALTDATA: FREE)
  • 6-Amino-3,4-dihydro-3-oxo-2H-1,4-benzoxazine
  • 6-Amino-3-oxo-3,4-dihydrobenzo[1,4]oxazine
  • 6-AMino-3,4-dihydro-2H-1,4-benzoxazin-3-one
  • 6-amino-2,4-dihydro-1,4-benzoxazin-3-one
  • 6-Amino-2H-1,4-benzoxazin-3(4H)-one 97%
  • 6-amino-4H-1,4-benzoxazin-3-one
  • Barbituric Acid Impurity 18
  • 6-Amino-2<i>H</i>-1,4-benzoxazin-3(4<i>H</i>)-one
  • 89976-75-0