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SW-100

Product Name
SW-100
CAS No.
2126744-35-0
Chemical Name
SW-100
Synonyms
SW-100;SW-100, 10 mM in DMSO;HDAC,SW-100,Histone deacetylases,Inhibitor,SW 100,inhibit,SW100;4-[(6-chloro-3,4-dihydro-2H-quinolin-1-yl)methyl]-N-hydroxybenzamide;4-((6-CHLORO-3,4-DIHYDROQUINOLIN-1(2H)-YL)METHYL)-N-HYDROXYBENZAMIDE;4-[(6-chloro-1,2,3,4-tetrahydroquinolin-1-yl)methyl]-N-hydroxybenzamide;Benzamide, 4-[(6-chloro-3,4-dihydro-1(2H)-quinolinyl)methyl]-N-hydroxy-
CBNumber
CB74918296
Molecular Formula
C17H17ClN2O2
Formula Weight
316.78
MOL File
2126744-35-0.mol
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SW-100 Property

storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 125 mg/mL (394.60 mM)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0087024
Product name
SW-100
Purity
99.92%
Packaging
5mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-0087024
Product name
SW-100
Purity
99.92%
Packaging
10mg
Price
$350
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0009821
Product name
SW-100
Purity
95.00%
Packaging
5MG
Price
$453.51
Updated
2021/12/16
ChemScene
Product number
CS-0087024
Product name
SW-100
Purity
99.92%
Packaging
50mg
Price
$850
Updated
2021/12/16
ChemScene
Product number
CS-0087024
Product name
SW-100
Purity
99.92%
Packaging
100mg
Price
$1500
Updated
2021/12/16
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SW-100 Chemical Properties,Usage,Production

Uses

SW-100 HDAC6 Inhibitor is used in methods of treating PACS1 and PACS2 syndromes comprising administering an HDAC6 or SIRT2 inhibitor in relation to restoring Golgi morphology in a cell.

in vivo

SW-100 (20 mg/kg; i.p.; twice a day for two days) ameliorates several memory and learning impairments including novel object recognition, temporal ordering, and coordinate and categorical spatial processing in mouse model of Fragile X syndrome[1].

Animal Model:8-10 weeks old C57BL/6 mice (Fmr1-/- mice)[1]
Dosage:20 mg/kg
Administration:Intraperitoneal injection; twice a day for two days
Result:Ameliorated several memory and learning impairments including novel object recognition, temporal ordering, and coordinate and categorical spatial processing in Fmr1-/- mice。

IC 50

HDAC1: 5.23 μM (IC50); HDAC2: 32.8 μM (IC50); HDAC3: 29.5 μM (IC50); HDAC4: 10.9 μM (IC50); HDAC5: 4.07 μM (IC50); HDAC6: 2.3 nM (IC50); HDAC7: 4.55 μM (IC50); HDAC8: 3.72 μM (IC50); HDAC9: 3.46 μM (IC50); HDAC10: 26.2 μM (IC50); HDAC11: 5.72 μM (IC50)

SW-100 Preparation Products And Raw materials

Raw materials

Preparation Products

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SW-100 Suppliers

China 52 United States 2 Global 54
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4757
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9126
Advantage
58
Shanghai Han-Xiang Chemical Co., Ltd.
Tel
15971444841
Fax
18327183813
Email
amber@biochempartner.com
Country
China
ProdList
3061
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
Chengdu Peter-like Biotechnology Co., Ltd.
Tel
18108052721
Email
2850505130@qq.com
Country
China
ProdList
5167
Advantage
58
Baimei Jihua (Henan) Pharmaceutical Technology Co., Ltd
Tel
037188900765 18037465274
Fax
QQ3430974218
Email
enyawanglei@sina.cn
Country
China
ProdList
13965
Advantage
58

2126744-35-0, SW-100Related Search:


  • SW-100
  • Benzamide, 4-[(6-chloro-3,4-dihydro-1(2H)-quinolinyl)methyl]-N-hydroxy-
  • 4-((6-CHLORO-3,4-DIHYDROQUINOLIN-1(2H)-YL)METHYL)-N-HYDROXYBENZAMIDE
  • HDAC,SW-100,Histone deacetylases,Inhibitor,SW 100,inhibit,SW100
  • 4-[(6-chloro-1,2,3,4-tetrahydroquinolin-1-yl)methyl]-N-hydroxybenzamide
  • SW-100, 10 mM in DMSO
  • 4-[(6-chloro-3,4-dihydro-2H-quinolin-1-yl)methyl]-N-hydroxybenzamide
  • 2126744-35-0