Uses
ChemicalBook > CAS DataBase List > AMINOGUANIDINE HYDROCHLORIDE

AMINOGUANIDINE HYDROCHLORIDE

Uses
Product Name
AMINOGUANIDINE HYDROCHLORIDE
CAS No.
1937-19-5
Chemical Name
AMINOGUANIDINE HYDROCHLORIDE
Synonyms
2-aminoguanidine hydrochloride;Aminoguanidine HCL;GUANYLHYDRAZINEHCL;AMINOGUANIDINE SALT;Aminoguanidine salts;CP-12009-18 tartrate;amino-guanidinhydrochloride;Aminoguanidine hydrochoride;Aminoguanadine hydrochloride;AMINOGUANIDINE HYDROCHLORIDE
CBNumber
CB7497900
Molecular Formula
CH7ClN4
Formula Weight
110.54608
MOL File
1937-19-5.mol
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AMINOGUANIDINE HYDROCHLORIDE Property

Melting point:
162-166 °C(lit.)
vapor pressure 
0Pa at 25℃
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Completely soluble in water
form 
Crystals
color 
White to off-white
Water Solubility 
506.7g/L at 20℃
Merck 
13,440
BRN 
3909606
LogP
-3.55 at 20℃
CAS DataBase Reference
1937-19-5(CAS DataBase Reference)
EPA Substance Registry System
Hydrazinecarboximidamide, monohydrochloride (1937-19-5)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
ME8430000
10-21
HS Code 
29280000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
396494
Product name
Aminoguanidine hydrochloride
Purity
≥98%
Packaging
25g
Price
$70.3
Updated
2024/03/01
Sigma-Aldrich
Product number
396494
Product name
Aminoguanidine hydrochloride
Purity
≥98%
Packaging
100g
Price
$214
Updated
2024/03/01
TCI Chemical
Product number
A1129
Product name
Aminoguanidine Hydrochloride
Purity
>98.0%(T)
Packaging
25g
Price
$52
Updated
2024/03/01
TCI Chemical
Product number
A1129
Product name
Aminoguanidine Hydrochloride
Purity
>98.0%(T)
Packaging
100g
Price
$113
Updated
2024/03/01
Cayman Chemical
Product number
81530
Product name
Aminoguanidine (hydrochloride)
Purity
≥98%
Packaging
10g
Price
$25
Updated
2024/03/01
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AMINOGUANIDINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Aminoguanidine Hydrochloride is used in the synthetic preparation of highly selective and potent G-protein-coupled receptor kinase 2 (GRK2) inhibitor for potential treatment of heart failure.

Description

Aminoguanidine is equipotent to L-NMMA and L-NNA as an inhibitor of iNOS. The IC50 values for inhibition of mouse iNOS and rat nNOS are 5.4 and 160 μM, respectively. Aminoguanidine also inhibits induction of iNOS protein expression by endotoxin in rat macrophages.

Chemical Properties

white to off-white crystals

Uses

antitussive

Uses

Aminoguanidine hydrochloride may be employed as nitric oxide synthase (NOS) inhibitor to investigate its effect on the reduction of alveolar bone loss in ligature induced periodontitis in rats. It may be used in the synthesis of 5-guanylhydrazone derivatives, having antibacterial activity against antibacterial activity against both Escherichia coli and Staphylococcus aureus.

Uses

a-Glucosidase inhibitor; hydroxyethyl derivative of 1-deoxynojirimycin

General Description

Aminoguanidine hydrochloride has been reported in a study as inhibitor of animal nitric oxide (NO)-synthase. Crystal structure of aminoguanidine hydrochloride has been investigated by Fourier and least squares method. Its crystals were monoclinic and the guanidine part of the aminoguanidinium ion is planar.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Inhibits both constitutive and inducible nitric oxide synthetase.

AMINOGUANIDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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AMINOGUANIDINE HYDROCHLORIDE Suppliers

Matrix Fine Chemicals GmbH
Tel
--
Fax
--
Email
nfo@matrix-fine-chemicals.com
Country
Switzerland
ProdList
6968
Advantage
58
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from AMINOGUANIDINE HYDROCHLORIDE manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Aminoguanidine Hydrochloride 1937-19-5
Price
US $85.00-25.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-22
Hebei Weibang Biotechnology Co., Ltd
Product
AMINOGUANIDINE HYDROCHLORIDE 1937-19-5
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-05
airuikechemical co., ltd.
Product
aminoguanidine hydrochloride 1937-19-5
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-08

1937-19-5, AMINOGUANIDINE HYDROCHLORIDERelated Search:


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  • 1937-19-5
  • 1973-19-5
  • NH2NHCNHNH2HCl
  • CH7ClN4
  • CH6N4HClH2NNHCNHNH2HCl
  • CH6N4ClH
  • Signalling
  • TUSACAPINE
  • Nitric Oxide
  • Pharmaceutical Intermediates