RO 90-7501

Product Name: RO 90-7501
CAS No.: 293762-45-5
Chemical Name: RO 90-7501
Synonyms: RO90-7501; RO 907501;2,5'-Bi-1H-benzimidazol]-5-amine, 2'-(4-aminophenyl)-;2'-(4-aMinophenyl)-1H,3'H-2,5'-bibenzo[d]iMidazol-6-aMine;2'-(4-Aminophenyl)-1H,3'H-[2,5'-bibenzo[d]imidazol]-5-amine
CBNumber: CB7498376
Molecular Formula: C20H16N6
Formula Weight: 340.388
MOL File: 293762-45-5.mol

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RO 90-7501 Property

storage temp.: Store at +4°C
solubility: DMSO: ~20mg/mL
form: solid
color: brown

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 18881
Product name: Ro 90-7501
Purity: ≥98%
Packaging: 5mg
Price: $90
Updated: 2024/03/01

Cayman Chemical

Product number: 18881
Product name: Ro 90-7501
Purity: ≥98%
Packaging: 10mg
Price: $171
Updated: 2024/03/01

Cayman Chemical

Product number: 18881
Product name: Ro 90-7501
Purity: ≥98%
Packaging: 25mg
Price: $400
Updated: 2024/03/01

Cayman Chemical

Product number: 18881
Product name: Ro 90-7501
Purity: ≥98%
Packaging: 50mg
Price: $710
Updated: 2024/03/01

TRC

Product number: R678450
Product name: Ro90-7501
Packaging: 2.5mg
Price: $265
Updated: 2021/12/16

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RO 90-7501 Chemical Properties,Usage,Production

Uses

Ro 90-7501 exhibits antibacterial activity. In addition, it also promote both toll-like receptor 3 (TLR3) and RIG-I-like receptor (RLR) ligand-induced IFN-β gene expression and antiviral response.

Definition

ChEBI: 2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine is a member of benzimidazoles.

Biological Activity

Inhibitor of amyloid β 42 (A β 42) fibril assembly; reduces A β 42-induced toxicity (EC 50 = 2 μ M).

in vivo

Ro 90-7501 (5 μg/g; intraperitoneal injection; daily; for 21 days; female BALB/c nude mice) treatment significantly delays tumor growth and significantly decreases tumor volume^[1].

Animal Model:	Female BALB/c nude mice (8-week-old) with HeLa cells under irradiation^[1]
Dosage:	5 μg/g
Administration:	Intraperitoneal injection; daily; for 21 days
Result:	Tumor growth was significantly delayed in the combination group. Tumor volume was also significantly decreased in the irradiation group.

IC 50

Amyloid β42; ATM; Protein phosphatase 5; Apoptosis

storage

Store at +4°C

RO 90-7501 Preparation Products And Raw materials

Raw materials

Preparation Products

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RO 90-7501 Suppliers

China 36 Germany 1 Japan 1 Switzerland 1 United Kingdom 1 United States 6 Global 46

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293762-45-5, RO 90-7501Related Search:

Silver RO 90-7501 4-(5-METHYL-1 H-BENZOIMIDAZOL-2-YL)-PHENYLAMINE TOSLAB 147928 TOSLAB 147924 4-(1H-IMIDAZOL-2-YL)-PHENYLAMINE 5-METHYL-2-PHENYL-1H-BENZO[D]IMIDAZOLE 4-(1H-BENZOIMIDAZOL-2-YL)-PHENYLAMINE

2'-(4-aMinophenyl)-1H,3'H-2,5'-bibenzo[d]iMidazol-6-aMine

RO90-7501; RO 907501

2'-(4-Aminophenyl)-1H,3'H-[2,5'-bibenzo[d]imidazol]-5-amine

2,5'-Bi-1H-benzimidazol]-5-amine, 2'-(4-aminophenyl)-

293762-45-5