ChemicalBook > CAS DataBase List > 4-Ethynylbenzonitrile

4-Ethynylbenzonitrile

Product Name
4-Ethynylbenzonitrile
CAS No.
3032-92-6
Chemical Name
4-Ethynylbenzonitrile
Synonyms
(4-Cyanophenyl)ethyne;4-Cyanophenylacetylene;1-Cyano-4-ethynylbenzene;Benzonitrile, 4-ethynyl-;4-ETHYNYLBENZONITRILE 97;4-Ethynylbenzonitrile 97%;Benzonitrile, 4-ethynyl- (9CI)
CBNumber
CB7498992
Molecular Formula
C9H5N
Formula Weight
127.14
MOL File
3032-92-6.mol
More
Less

4-Ethynylbenzonitrile Property

Melting point:
156-160 °C(lit.)
Boiling point:
230.2±23.0 °C(Predicted)
Density 
1.037 g/mL at 25 °C(lit.)
Flash point:
>110 °C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Solid
color 
Pale yellow
Water Solubility 
Slightly soluble in water.
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-36
WGK Germany 
3
HS Code 
2926907090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
206539
Product name
4-Ethynylbenzonitrile
Purity
97%
Packaging
5g
Price
$256.2
Updated
2025/07/31
TCI Chemical
Product number
E0872
Product name
4-Ethynylbenzonitrile
Purity
min. 97.0 %
Packaging
1G
Price
$71
Updated
2025/07/31
TCI Chemical
Product number
E0872
Product name
4-Ethynylbenzonitrile
Purity
min. 97.0 %
Packaging
5G
Price
$213
Updated
2025/07/31
TRC
Product number
E932163
Product name
4-Ethynylbenzonitrile
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
E932163
Product name
4-Ethynylbenzonitrile
Packaging
500mg
Price
$65
Updated
2021/12/16
More
Less

4-Ethynylbenzonitrile Chemical Properties,Usage,Production

Uses

4-Ethynylbenzonitrile is used as a synthetic fragment and as a test compound for cross-coupling reactions. It is used in the study of hydrogen bond formation in multifunctional molecules due to the presence of four hydrogen bonding sites. It is also involved in the preparation of 4-[(trimethylsilyl)ethynyl]benzonitrile.

General Description

The water complexes formed with 4-ethynylbenzonitrile (4EBzN) were studied using IR-UV double resonance spectroscopy.

Synthesis

75867-40-2

3032-92-6

General procedure for the synthesis of 4-ethynylbenzonitrile from 4-[(trimethylsilyl)ethynyl]benzyl cyanide: potassium carbonate (50 mg, 0.36 mmol) was added to a mixed methanol/tetrahydrofuran solution (16 mL, 1:1) of 4-[(trimethylsilyl)ethynyl]benzyl cyanide (1.1 g, 5.3 mmol). The reaction mixture was stirred at room temperature for 30 min, followed by removal of the solvent by rotary evaporator. The residue was diluted with ethyl acetate and washed sequentially with 10% aqueous hydrochloric acid and saturated saline. The organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give 4-ethynylbenzonitrile as a white solid (0.61 g, 4.80 mmol, 91% yield).

References

[1] Tetrahedron, 2003, vol. 59, # 3, p. 287 - 293
[2] Journal of Medicinal Chemistry, 1998, vol. 41, # 21, p. 4036 - 4052
[3] Journal of the American Chemical Society, 1997, vol. 119, # 43, p. 10401 - 10412
[4] Journal of Organic Chemistry, 2014, vol. 79, # 16, p. 7342 - 7357
[5] New Journal of Chemistry, 2017, vol. 41, # 6, p. 2296 - 2308

4-Ethynylbenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-Ethynylbenzonitrile Suppliers

China 130 Europe 1 Germany 1 India 2 Switzerland 1 United Kingdom 2 United States 10 Global 147
Shanghai Puhao Chemical Technology Co. Ltd.
Tel
13761817188
Email
774028079@qq.com
Country
China
ProdList
291
Advantage
58
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Tetranov Biopharm
Tel
13526569071
Email
sales@leadmedpharm.com
Country
China
ProdList
7892
Advantage
64
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3199
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Shanghai Run-Biotech Co., Ltd.
Tel
021-57171705 13817537615
Fax
QQ3095748324
Email
sales@run-biotech.com
Country
China
ProdList
2337
Advantage
58
Shanghai GAOXIANG Chemical Co., Ltd.
Tel
021-57816257 18930243658
Fax
021-57816257
Email
fecpo@139.com
Country
China
ProdList
295
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5219
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15873
Advantage
55
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 18626450290
Email
yftan@aikonchem.com
Country
China
ProdList
16679
Advantage
50
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
skychemical Co.Ltd
Tel
021-20960837,QQ1332204249
Fax
021-20960837
Email
sales@skychemical.com
Country
China
ProdList
3341
Advantage
55
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9021
Advantage
60
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9627
Advantage
58
Nanjing XiLang Chemical Products Co., Ltd.
Tel
18936048580
Email
chemxilang@163.com
Country
China
ProdList
3909
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Shanghai Changyan Chem & Tech Co., Ltd.
Tel
021-20242659 18930833303
Fax
+86 (21) 2024-2659
Email
Sales@changyanchem.cn
Country
China
ProdList
5001
Advantage
55
Lancrix Chemicals
Tel
86-21-50817262
Fax
86-21-57712035
Email
sales@lancrix.com
Country
China
ProdList
1502
Advantage
55
Zhengzhou AnMusi Chemical Products Co., Ltd.
Tel
0371-55289822 18737195735
Fax
QQ：2370407954
Email
2370407954@qq.com
Country
China
ProdList
1981
Advantage
55
Henan Jiuhua Biological Technology Co., Ltd.
Tel
15738884691 153248764872949584887 237654463
Fax
0371-55320919
Email
jiuhuabiochem@163.com
Country
China
ProdList
2750
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Nafu Biotechnology Co., Ltd.
Tel
021-58952328 13125124762
Fax
021-58952328
Email
sale@chemhui.com
Country
China
ProdList
510
Advantage
55
Shanghai Kangman Biological Technology Co., Ltd.
Tel
18800375331
Fax
021-50908862
Email
kangmansales@163.com
Country
China
ProdList
7570
Advantage
55
Zhengzhou Huiju Chemical Co., Ltd.
Tel
0371-55900031 18137872243
Fax
QQ：2853979815
Email
2853979815@qq.com
Country
China
ProdList
9975
Advantage
55
Suzhou Ruichi Pharmaceutical Technology Co., Ltd.
Tel
0512-50152853
Fax
0512-50152853
Email
jjks1111@126.com
Country
China
ProdList
623
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19800
Advantage
60
Chengdu Focus Pharmaceutical Technology Co., Ltd.
Tel
028-64950838 17340131597
Email
bd-focus@focuspharm.com
Country
China
ProdList
850
Advantage
58
Shanghai BaiShun Biological Technology Co., Ltd
Tel
021-37581181
Fax
021-57456066
Email
sales@chem-mall.com
Country
China
ProdList
10330
Advantage
58
Jiaxing Deyi Chemical Co., Ltd.
Tel
86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8593
Advantage
58
More
Less

View Lastest Price from 4-Ethynylbenzonitrile manufacturers

Shanghai UCHEM Inc.
Product
4-Ethynylbenzonitrile 3032-92-6
Price
US $25.00-407.00/g
Min. Order
5g
Purity
0.97
Supply Ability
10kg
Release date
2023-12-04
Career Henan Chemical Co
Product
4-ETHYNYLBENZONITRILE 97 3032-92-6
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-08

3032-92-6, 4-EthynylbenzonitrileRelated Search:

2-Amino-5-(1-methylethyl)benzonitrile 3-Ethylbenzonitrile (R)-3-(1-aminoethyl)benzonitrile 3-Methyl-2-(3,4-dimethoxyphenyl)butyronitrile 4-CYANOPHENYLETHYLAMINE HCL 4-Ethylbenzonitrile (S)-3-(1-Aminoethyl)benzonitrile 4-Ethynylbenzonitrile 4-(3-HYDROXY-PROP-1-YNYL)-BENZONITRILE 4-(2-PHENYLETH-1-YNYL)BENZONITRILE 4-(4-METHOXY-PHENYLETHYNYL)-BENZONITRILE 4-(3-HYDROXY-1-BUTYNYL)BENZONITRILE 4-(3-HYDROXY-3-METHYL-1-BUTYNYL)BENZONITRILE 4-(2'-TRIMETHYLSILYLETHYNYL)BENZONITRILE 4-O-TOLYLETHYNYL-BENZONITRILE 4-HEX-1-YNYLBENZONITRILE 4-(2-BROMO-PHENYLETHYNYL)-BENZONITRILE 4-(3-METHOXY-PHENYLETHYNYL)-BENZONITRILE

  • 4-Cyanophenylacetylene
  • (4-Cyanophenyl)ethyne
  • 1-Cyano-4-ethynylbenzene
  • 4-Ethynylbenzonitrile 97%
  • 4-ETHYNYLBENZONITRILE 97
  • Benzonitrile, 4-ethynyl- (9CI)
  • Benzonitrile, 4-ethynyl-
  • 3032-92-6
  • HC8801CC6H4CN
  • HCCC6H4CN
  • C9H5N
  • C8 to C9
  • Cyanides/Nitriles
  • Nitrogen Compounds