2-Amino-5-(1-methylethyl)benzonitrile
- Product Name
- 2-Amino-5-(1-methylethyl)benzonitrile
- CAS No.
- 549488-76-8
- Chemical Name
- 2-Amino-5-(1-methylethyl)benzonitrile
- Synonyms
- 2-amino-5-isopropylbenzonitrile;2-aMino-5-(propan-2-yl)benzonitrile;2-Amino-5-(1-methylethyl)benzonitrile;Benzonitrile, 2-amino-5-(1-methylethyl)-;2-amino-5-isopropylbenzonitrile - [AC78501];Benzonitrile, 2-amino-5-(1-methylethyl)- (9CI)
- CBNumber
- CB81049824
- Molecular Formula
- C10H12N2
- Formula Weight
- 160.22
- MOL File
- 549488-76-8.mol
2-Amino-5-(1-methylethyl)benzonitrile Property
- Boiling point:
- 285.8±33.0 °C(Predicted)
- Density
- 1.04±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 2.21±0.10(Predicted)
- Appearance
- Yellow to brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A613795
- Product name
- 2-Amino-5-(1-methylethyl)benzonitrile
- Packaging
- 100mg
- Price
- $295
- Updated
- 2021/12/16
- Product number
- FA150915
- Product name
- 2-Amino-5-(1-methylethyl)benzonitrile
- Packaging
- 500mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- FA150915
- Product name
- 2-Amino-5-(1-methylethyl)benzonitrile
- Packaging
- 50mg
- Price
- $51
- Updated
- 2021/12/16
- Product number
- FA150915
- Product name
- 2-Amino-5-(1-methylethyl)benzonitrile
- Packaging
- 100mg
- Price
- $88
- Updated
- 2021/12/16
- Product number
- 076460
- Product name
- 2-Amino-5-isopropylbenzonitrile
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $445
- Updated
- 2021/12/16
2-Amino-5-(1-methylethyl)benzonitrile Chemical Properties,Usage,Production
Synthesis
51605-97-1
544-92-3
549488-76-8
General procedure for the synthesis of 2-amino-5-(1-methylethyl)benzonitrile from 2-bromo-4-isopropylaniline and cuprous cyanide (I): a mixture of cuprous cyanide (I) (2.5 g, 28.02 mmol) and 2-bromo-4-isopropylaniline (5.0 g, 23.35 mmol) was heated in 1-methyl-2-pyrrolidinone (20 mL) to 195°C for for 4 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate (100 mL) to give a dark solution. It was washed twice sequentially with 28% aqueous ammonium hydroxide, twice with saturated aqueous sodium chloride solution (brine) and twice with water. The organic layer was separated, dried with anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. The product was purified by fast column chromatography with hexane as the starting eluent, and the gradient was increased to 20% ethyl acetate/80% hexane to give the orange oily product 2-amino-5-(1-methylethyl)benzonitrile (3.31 g, 20.66 mmol, 88% yield). Mass spectrum (m/z): 161 (M + 1).
References
[1] Patent: WO2004/14895, 2004, A1. Location in patent: Page 65-66
[2] Patent: WO2004/14895, 2004, A1. Location in patent: Page 62
2-Amino-5-(1-methylethyl)benzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Amino-5-(1-methylethyl)benzonitrile manufacturers
- Product
- 2-Amino-5-(1-methylethyl)benzonitrile 549488-76-8
- Price
- US $5.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-12