DIGITALIS (3 G) Property

EPA Substance Registry System

Digitalis (8031-42-3)

Safety

HS Code 

2938900000

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

DIGITALIS (3 G) Chemical Properties,Usage,Production

Biological Functions

Lanatoside A is composed of the aglycone digitoxigenin (genin indicates no sugar) connected to three digitoxose sugar molecules, the third of which carries a 3-acetyl group, and a terminal glucose molecule. In other words, the structure sequence is glucose4-3-acetyldigitoxose3-digitoxose2- digitoxose1-digitoxigenin.
Lanatoside B has the identical sugar portion to lanatoside A, except that the aglycone has extra hydroxyl group at C-16 and is given the name gitoxigenin. The structural sequence is glucose4-3- acetyldigitoxose3-digitoxose2-digitoxose1-gitoxigenin.
Lanatoside C also has the same sugars found in both lanatosides A and B; however, the aglycone has the nucleus of lanatoside A plus an additional hydroxyl group at C-12. This cardenolide is named digoxigenin. The structural sequence is glucose4-3-acetyldigitoxose3-digitoxose2-digitoxose1- digoxigenin.
Partial hydrolysis of the glucose molecule and the acetate group from lanatoside A and C produces, respectively, two new and most important cardiac glycosides, digitoxin and digoxin, with the following sequences: digitoxin, (digitoxose)3-digitoxigenin; and digoxin, (digitoxose)3-digoxigenin.