3-ETHYNYLANISOLE 96
Uses- Product Name
- 3-ETHYNYLANISOLE 96
- CAS No.
- 768-70-7
- Chemical Name
- 3-ETHYNYLANISOLE 96
- Synonyms
- 3-Ethynylanisole;3-Ethynyl Anisol;3-ETHYNYLANISOLE 96;1-Etynyl-3-Methoxy-Benzene;3-Methoxyphenylacetylene,96%;Benzene, 1-ethynyl-3-Methoxy-;3-Methoxyphenylacetylene, tech;Benzene, 1-ethynyl-3-methoxy- (9CI);1-Ethynyl-3-methoxybenzene, 3-Ethyny;1-ethynyl-3-methoxybenzene - [E25312]
- CBNumber
- CB7504491
- Molecular Formula
- C9H8O
- Formula Weight
- 132.16
- MOL File
- 768-70-7.mol
3-ETHYNYLANISOLE 96 Property
- Boiling point:
- 204-210 °C (lit.)
- Density
- 1.04 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.555(lit.)
- Flash point:
- 170 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- clear liquid
- color
- Colorless to Light orange to Yellow
- Water Solubility
- Slightly soluble in water.
- InChI
- InChI=1S/C9H8O/c1-3-8-5-4-6-9(7-8)10-2/h1,4-7H,2H3
- InChIKey
- ZASXCTCNZKFDTP-UHFFFAOYSA-N
- SMILES
- C1(C#C)=CC=CC(OC)=C1
Safety
- Risk Statements
- 10
- Safety Statements
- 3/9/49-15-36/37/39-43
- RIDADR
- UN 3334
- WGK Germany
- 3
- HS Code
- 29093090
N-Bromosuccinimide Price
- Product number
- 519413
- Product name
- 3-Ethynylanisole
- Purity
- 96%
- Packaging
- 5g
- Price
- $290
- Updated
- 2025/07/31
- Product number
- E0627
- Product name
- 3-Ethynylanisole
- Purity
- >97.0%(GC)
- Packaging
- 1g
- Price
- $52
- Updated
- 2025/07/31
- Product number
- E0627
- Product name
- 3-Ethynylanisole
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $174
- Updated
- 2025/07/31
- Product number
- E685075
- Product name
- 3-Ethynylanisole
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- E25312
- Product name
- 1-ethynyl-3-methoxybenzene
- Purity
- 97.0%
- Packaging
- 1g
- Price
- $40
- Updated
- 2021/12/16
3-ETHYNYLANISOLE 96 Chemical Properties,Usage,Production
Uses
3-Ethynylanisole is a useful research chemical.
Uses
It is a useful aromatic compound.
Synthesis
253684-23-0
768-70-7
To a dichloromethane solution of CBr4 (9.70 g, 29.4 mmol) was slowly added a dichloromethane solution of PPh3 (15.4 g, 58.8 mmol) at 0 °C. After stirring for 5 min, m-anisaldehyde (1.99 g, 14.6 mmol) was added to the reaction system and stirring was continued for 20 min. After completion of the reaction, water and dichloromethane were added for dilution. The organic layer was separated, washed sequentially with saturated NaHCO3 solution and brine, dried over anhydrous MgSO4 and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: hexane) to afford 2',2'-dibromo vinyl-3-methoxybenzene (2.00 g, 6.80 mmol, 92% yield) as a colorless oil.1H NMR (CDCl3, 400 MHz) data were as follows: δ= 3.82 (s, 3H), 6.91 (dd, 1H, J = 8.2, 2.3 Hz) , 7.12 (d, 1H, J = 8.2 Hz), 7.15 (d, 1H, J = 2.3 Hz), 7.29 (t, 1H, J = 8.2 Hz), 7.48 (s, 1H). To a tetrahydrofuran solution of 3-(2',2'-dibromovinyl)methoxybenzene (1.80 g, 6.20 mmol) was added dropwise n-butyllithium (2.6 M hexane solution; 5.00 ml, 13.0 mmol) at -78 °C. After stirring for 15 minutes, the reaction was quenched by the addition of saturated NH4Cl solution and the reaction mixture was slowly warmed to room temperature. The mixture was extracted with ether, the organic layers were combined, washed sequentially with saturated NaHCO3 solution and brine, dried over anhydrous MgSO4 and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: hexane/ethyl acetate=10:1) to afford 3-ethynyl anisole (472 mg, 3.57 mmol, 58% yield) as a colorless oil.
References
[1] Tetrahedron Letters, 2011, vol. 52, # 9, p. 992 - 994
[2] Organic Letters, 2009, vol. 11, # 1, p. 229 - 231
[3] Advanced Synthesis and Catalysis, 2015, vol. 357, # 2-3, p. 553 - 560
[4] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 22, p. 5127 - 5132
[5] Heterocyclic Communications, 2016, vol. 22, # 3, p. 165 - 167
3-ETHYNYLANISOLE 96 Preparation Products And Raw materials
Raw materials
Preparation Products
3-ETHYNYLANISOLE 96 Suppliers
- Tel
- 13120563767
- Fax
- 15669989863
- chemchen925@outlook.com
- Country
- China
- ProdList
- 987
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
- Tel
- 13526569071
- sales@leadmedpharm.com
- Country
- China
- ProdList
- 7892
- Advantage
- 64
View Lastest Price from 3-ETHYNYLANISOLE 96 manufacturers
- Product
- 3-Ethynylanisole 768-70-7
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-11-13
- Product
- 3-ETHYNYLANISOLE 96 768-70-7
- Price
- US $2.00/KG
- Min. Order
- 1g
- Purity
- 98%MIN
- Supply Ability
- ASK
- Release date
- 2020-01-07