VENTURICIDIN A
- Product Name
- VENTURICIDIN A
- CAS No.
- 33538-71-5
- Chemical Name
- VENTURICIDIN A
- Synonyms
- a-130;aa-0368;venturicidinb,3’-carbamate;HHQKNFDAEDTRJK-WLJINWSWSA-N;4,21-Dioxabicyclo[15.3.1]heneicosa-9,15,18-trien-3-one, 11-[[3-O-(aminocarbonyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]-1-hydroxy-5-[(1R,3R,4S,5S)-4-hydroxy-1,3,5-trimethyl-6-oxooctyl]-6,8,16,18-tetramethyl-, (1R,5S,6R,8R,9E,11R,15E,17R)-
- CBNumber
- CB7505296
- Molecular Formula
- C41H67NO11
- Formula Weight
- 749.97
- MOL File
- 33538-71-5.mol
VENTURICIDIN A Property
- Melting point:
- 145-147°; mp 140-142°
- alpha
- D +119° (c = 0.5 in chloroform)
- Boiling point:
- 874.9±65.0 °C(Predicted)
- Density
- 1.16±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- pka
- 11.80±0.70(Predicted)
- form
- White to off-white solid.
- color
- White to off-white
Safety
- RTECS
- YX4556000
- HS Code
- 2941900000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 15377
- Product name
- Venturicidin A
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $125
- Updated
- 2024/03/01
- Product number
- 15377
- Product name
- Venturicidin A
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $500
- Updated
- 2024/03/01
- Product number
- V121003
- Product name
- VenturicidinA
- Packaging
- 1mg
- Price
- $635
- Updated
- 2021/12/16
- Product number
- C4641
- Product name
- VenturicidinA
- Packaging
- 5mg
- Price
- $1005
- Updated
- 2021/12/16
- Product number
- BVT-0454-M001
- Product name
- VenturicidinA
- Purity
- ≥98%(1H-NMR,HPLC)
- Packaging
- 1mg
- Price
- $120
- Updated
- 2021/12/16
VENTURICIDIN A Chemical Properties,Usage,Production
Description
Venturicidin A is a macrolide antibiotic isolated from strains of Streptomyces. It is active against fungi in the genus Venturia which cause apple scab, as well as other fungi, but not against higher plants. Venturicidin A is also cytotoxic against trypanosomes (IC50 = 120-
Uses
The macrolide antibiotic, Venturicidin A, isolated from a Streptomyces sp., is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. Venturicidin A was originally isolated as an antifungal agent.
Uses
Venturicidin A is an antibiotic and potent inhibitor of mitochondrial ATP synthase.
Definition
ChEBI: Venturicidin a is a diterpene lactone.
IC 50
Aminoglycoside
References
[1] A. RHODES. Venturicidin: A New Antifungal Antibiotic of Potential Use in Agriculture[J]. Nature, 1961, 192 4806: 952-954. DOI: 10.1038/192952a0
[2] DAVID S. PERLIN Alan E S Lisa R Latchney. Inhibition of Escherichia coli H+-ATPase by venturicidin, oligomycin and ossamycin[J]. Biochimica et Biophysica Acta-Bioenergetics, 1985, 807 3: Pages 238-244. DOI: 10.1016/0005-2728(85)90254-3
[3] A MATSUNO-YAGI Y H. Studies on the mechanism of oxidative phosphorylation. ATP synthesis by submitochondrial particles inhibited at F0 by venturicidin and organotin compounds.[J]. The Journal of Biological Chemistry, 1993, 268 9: 6168-6173.
VENTURICIDIN A Preparation Products And Raw materials
Raw materials
Preparation Products
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