VALROCEMIDE
- Product Name
- VALROCEMIDE
- CAS No.
- 92262-58-3
- Chemical Name
- VALROCEMIDE
- Synonyms
- TV 1901;VALROCEMIDE;Valrocemide, >98%;Valrocemide(TV1901);N-Valproylglycinamide;Valrocemide (TV1901,VGD));Valrocemide, 10 mM in DMSO;N-(2-Amino-2-oxoethyl)-2-propylpentanamide;Pentanamide, N-(2-amino-2-oxoethyl)-2-propyl-;Valrocemide,Inhibitor,TV-1901,inhibit,TV 1901
- CBNumber
- CB7511549
- Molecular Formula
- C10H20N2O2
- Formula Weight
- 200.28
- MOL File
- 92262-58-3.mol
VALROCEMIDE Property
- Boiling point:
- 417.5±28.0 °C(Predicted)
- Density
- 0.997
- storage temp.
- Store at -20°C
- solubility
- DMF: 30mg/mL; DMSO: 30mg/mL; DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL; Ethanol: 25mg/mL
- form
- A solid
- pka
- 15.23±0.46(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B6100
- Product name
- Valrocemide
- Packaging
- 5mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- B6100
- Product name
- Valrocemide
- Packaging
- 25mg
- Price
- $270
- Updated
- 2021/12/16
- Product number
- API0025446
- Product name
- N-VALPROYLGLYCINAMIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $667.8
- Updated
- 2021/12/16
- Product number
- 7370AJ
- Product name
- Valrocemide
- Packaging
- 1g
- Price
- $937
- Updated
- 2021/12/16
- Product number
- DC9729
- Product name
- Valrocemide(TV1901,VGD))
- Purity
- >98%
- Packaging
- 250mg
- Price
- $700
- Updated
- 2021/12/16
VALROCEMIDE Chemical Properties,Usage,Production
Uses
Antiepileptic; anticonvulsant.
in vivo
In mice, valrocemide affords complete protection against maximal electroshock-, pentylenetetrazole-, picrotoxin-, and bicuculline-induced seizures and 6-Hz "psychomotor" seizures with median effective dose (ED50) values of 151, 132, 275, 248, and 237 mg/kg, respectively. Valrocemide is also effective in preventing sound-induced seizures in Frings audiogenic-seizure susceptible mice (ED50, 52 mg/kg). The median neurotoxic dose in mice is 332 mg/kg. After oral administration to rats, valrocemide is active in the MES test, with an ED50 of 73 mg/kg, and the median neurotoxic dose is 1,000 mg/kg. Intraperitoneal administration of 300 mg/kg of valrocemide to hippocampal kindled Sprague–Dawley rats block generalized seizures and shorten the afterdischarge duration significantly. Valrocemide also provides complete protection from focal seizures in the corneally kindled rats (ED50, 161 mg/kg)[1].
VALROCEMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
VALROCEMIDE Suppliers
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