CDK4/6-IN-2

Product Name: CDK4/6-IN-2
CAS No.: 1800506-48-2
Chemical Name: CDK4/6-IN-2
Synonyms: AM24679P4;CDK4/6-IN-2;CDK4/6 inhibitor 2;Cyclin dependent kinase,CDK-4/6-IN-2,CDK,CDK4/6 IN 2,CDK4/6IN2,inhibit,Inhibitor;5-((4-ethylpiperazin-1-yl)methyl)-N-(5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyridin-2-yl)pyrimidin-2-amine;2-Pyrimidinamine, 5-[(4-ethyl-1-piperazinyl)methyl]-N-[5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyridinyl]-
CBNumber: CB75419703
Molecular Formula: C27H32F2N8
Formula Weight: 506.59
MOL File: 1800506-48-2.mol

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CDK4/6-IN-2 Property

Boiling point:: 665.2±65.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 5.2 mg/mL (10.26 mM)
pka: 7.67±0.10(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0083151
Product name: CDK4/6-IN-2
Purity: 99.82%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0083151
Product name: CDK4/6-IN-2
Purity: 99.82%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0083151
Product name: CDK4/6-IN-2
Purity: 99.82%
Packaging: 50mg
Price: $1650
Updated: 2021/12/16

ChemScene

Product number: CS-0083151
Product name: CDK4/6-IN-2
Purity: 99.82%
Packaging: 100mg
Price: $2650
Updated: 2021/12/16

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CDK4/6-IN-2 Chemical Properties,Usage,Production

Description

CDK4/6-IN-2 is a potent CDK4 and CDK6 inhibitor extracted from patent US20180000819A1, Compound 1, has IC50s of 2.7 and 16 nM for CDK4 and CDK6, respectively[1]. CDK4|2.7 nM (IC50)|CDK6|16 nM (IC50)

CDK4/6-IN-2 inhibits H358, H441, PC3, MV-4-11, JeKo-1, SW780, and HGC-27 cells with IC50s of 290.9, 147.8, 260.5, 139, 36.98, 162.5, and 316.4 nM, respectively[1].

References

[1]. Frank Wu, et al. Kinase inhibitor and use thereof. US20180000819A1.

CDK4/6-IN-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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CDK4/6-IN-2 Suppliers

China 15 United States 2 Global 17

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
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MedChemExpress

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1800506-48-2, CDK4/6-IN-2Related Search:

CDK4/6-IN-2

CDK4/6 inhibitor 2

5-((4-ethylpiperazin-1-yl)methyl)-N-(5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyridin-2-yl)pyrimidin-2-amine

AM24679P4

Cyclin dependent kinase,CDK-4/6-IN-2,CDK,CDK4/6 IN 2,CDK4/6IN2,inhibit,Inhibitor

2-Pyrimidinamine, 5-[(4-ethyl-1-piperazinyl)methyl]-N-[5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyridinyl]-

1800506-48-2

CHFN