Applications Immunogen Background

GPI antibody

Applications Immunogen Background
Product Name
GPI antibody
Chemical Name
GPI antibody
Synonyms
GPI antibody;Rabbit Polyclonal GPI Antibody
CBNumber
CB75632102
Formula Weight
0
MOL File
Mol file
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb157284
Product name
GPI antibody
Purity
Affinity purified by Protein A
Packaging
100μg
Price
$421.6
Updated
2021/12/16
Biorbyt Ltd
Product number
orb157284
Product name
GPI antibody
Purity
Affinity purified by Protein A
Packaging
200μg
Price
$673.2
Updated
2021/12/16
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GPI antibody Chemical Properties,Usage,Production

Applications

The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity.

Immunogen

Anti-human GPI mAb, clone PAT22G2AT, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human GPI protein 1-558 amino acids purified from E. coli.

Background

Glucose-6-phosphate isomerase (GPI) is a part of the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. GPI is a dimeric enzyme which catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. Mammalian GPI also functions as a tumor-secreted cytokine and an angiogenic factor (AMF) which stimulates endothelial cell motility. In addition, GPI is a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. GPI performs in different capacities inside and outside the cell. In the cytoplasm, GPI is involved in glycolysis and gluconeogenesis, while outside the cell it acts as a neurotrophic factor for spinal and sensory neurons.
Defects in the GPI gene cause the nonspherocytic hemolytic anemia and a severe enzyme deficiency can be linked to hydrops fetalis, immediate neonatal death and neurological impairment.

GPI antibody Preparation Products And Raw materials

Raw materials

Preparation Products

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GPI antibody Suppliers

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