MT-ND3 antibody
Source Reactivity Background References- Product Name
- MT-ND3 antibody
- Chemical Name
- MT-ND3 antibody
- Synonyms
- MT-ND3 antibody
- CBNumber
- CB75664367
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb185335
- Product name
- MT-ND3 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb185335
- Product name
- MT-ND3 antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $673.2
- Updated
- 2021/12/16
MT-ND3 antibody Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human
Background
Mitochondrially encoded NADH dehydrogenase 3 is encoded by the mitochondrial gene MT-ND3 and is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase. Located in the mitochondrial inner membrane, Complex I is the largest of the five respiratory complexes and catalyzes electron transfer from NADH to ubiquinone. The mitochondrially encoded subunits of Complex I, including MT-ND3, are the most hydrophobic subunits and form the core of the transmembrane region. Pathogenic variants of the MT-ND3 gene are known to cause mitochondrial complex I deficiency and may lead to a wide range of clinical disorders, including Leigh syndrome, Leber hereditary optic neuropathy, and encephalopathy.
References
[1] Weiss, H. et al. (1991) Eur J Biochem 197, 563-76.
[2] Mimaki, M. et al. (2012) Biochim Biophys Acta 1817, 851-62.
[3] Sarzi, E. et al. (2007) Am J Med Genet A 143A, 33-41.
[4] La Morgia, C. et al. (2014) BMC Neurol 14, 116.
[5] McFarland, R. et al. (2004) Ann Neurol 55, 58-64.
MT-ND3 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
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