ChemicalBook > CAS DataBase List > SHU-9119
SHU-9119
- Product Name
- SHU-9119
- CAS No.
- 168482-23-3
- Chemical Name
- SHU-9119
- Synonyms
- SHU-9119;SHU9119,TFA;CHEMBL3422426;SHU9119 (trifluoroacetate salt);AC-NLE-ASP-HIS-D-2-NAL-ARG-TRP-LYS-NH2;AC-NLE-ASP-HIS-D-2-NAL-H2N-LYS-TRP-ARG;AC-NLE-ASP-HIS-D-NAL(2)-ARG-TRP-LYS-NH2;Ac-Nle-cyclo(-Asp-His-D-2-Nal-Arg-Trp-Lys-NH2);AC-NLE4-C[ASP5, D-NAL(2)7, LYS10]ALPHA-MSH (4-10)-NH2;AC-NLE-CYCLO[(BETA-D)-H-(D-2-NAL)-RW-(EPSILON-K)]-NH2
- CBNumber
- CB7675726
- Molecular Formula
- C54H71N15O9
- Formula Weight
- 1074.24
- MOL File
- 168482-23-3.mol
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SHU-9119 Property
- Density
- 1.43±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- H2O : 20 mg/mL (18.62 mM; Need ultrasonic)
- form
- Powder
- pka
- 13.00±0.70(Predicted)
- color
- White to off-white
- Water Solubility
- Soluble to 0.20 mg/ml in water
- Sequence
- Ac-Nle-Asp-His-D-Nal-Arg-Trp-Lys-NH2(Chemical Bridge Asp2-Lys7)
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 24152
- Product name
- SHU9119 (trifluoroacetate salt)
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $77
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 24152
- Product name
- SHU9119 (trifluoroacetate salt)
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $121
- Updated
- 2024/03/01
Tocris
- Product number
- 3420
- Product name
- SHU9119
- Packaging
- 1
- Price
- $151
- Updated
- 2021/12/16
Usbiological
- Product number
- 256659
- Product name
- SHU 9119
- Packaging
- 1mg
- Price
- $389
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-6496
- Product name
- SHU9119
- Purity
- 98.21%
- Packaging
- 5mg
- Price
- $468
- Updated
- 2021/12/16
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SHU-9119 Chemical Properties,Usage,Production
Description
SHU9119 is an agonist of melanocortin receptor 1 (MC1R) and antagonist of MC4R (IC50s = 1.2 and 2.9 nM, respectively, for displacement of melanocortin). It induces cAMP formation in HEK293 cells expressing human MC1R (EC50 = 1.11 nM), but inhibits cAMP formation in cells expressing human MC4R. In rats, SHU9119 (24 nmol, i.c.v. per day for seven days) increases food intake, body weight, fat mass, and lean mass, with concomitant increases in blood glucose, insulin, and leptin levels via disrupted melanocortin signaling. Similarly, mice treated with SHU9119 (5 nmol/day, i.c.v.) exhibit food intake-independent increases in body weight and fat mass consequent to MC4R inhibition and subsequent brown adipose tissue dysfunction.
storage
Store at -20°C
SHU-9119 Preparation Products And Raw materials
Raw materials
Preparation Products
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SHU-9119 Suppliers
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
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- China
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