FMOC-BETA-ALANINOL
- Product Name
- FMOC-BETA-ALANINOL
- CAS No.
- 157887-82-6
- Chemical Name
- FMOC-BETA-ALANINOL
- Synonyms
- Fmoc-b-Ala-ol;Fmoc-β-Ala-ol;Fmoc-β-Alaninol;FMOC-BETA-ALA-OL;FMOC-NH-(CH2)3-OH;FMOC-BETA-ALANINOL;FMOC-3-AMINOPROPANOL;N-FMOC-3-AMINOPROPANOL;FMOC-3-AMINO-1-PROPANOL;3-(FMOC-AMINO)-1-PROPANOL
- CBNumber
- CB7676501
- Molecular Formula
- C18H19NO3
- Formula Weight
- 297.35
- MOL File
- 157887-82-6.mol
FMOC-BETA-ALANINOL Property
- Melting point:
- 124-126
- Boiling point:
- 518.9±33.0 °C(Predicted)
- Density
- 1.212±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), DMSO (Slightly)
- form
- Solid
- pka
- 11.94±0.46(Predicted)
- color
- White to Off-White
- BRN
- 6814792
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- 47305
- Product name
- 3-(Fmoc-amino)-1-propanol
- Purity
- ≥98.0%
- Packaging
- 1g
- Price
- $42
- Updated
- 2023/06/20
- Product number
- F1036
- Product name
- 3-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-1-propanol
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 1g
- Price
- $134
- Updated
- 2025/07/31
- Product number
- F604270
- Product name
- Fmoc-β-alaninol
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
- Product number
- F604270
- Product name
- Fmoc-β-alaninol
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- CS-W002610
- Product name
- (9H-Fluoren-9-yl)methyl(3-hydroxypropyl)carbamate
- Purity
- 99.54%
- Packaging
- 5g
- Price
- $63
- Updated
- 2021/12/16
FMOC-BETA-ALANINOL Chemical Properties,Usage,Production
Chemical Properties
White powder
Uses
12989 REPLACED BY 12560
Uses
Fmoc-beta-alaninol
reaction suitability
reagent type: cross-linking reagent
Synthesis
28920-43-6
156-87-6
157887-82-6
The general procedure for the synthesis of 3-(Fmoc-amino)-1-propanol from methyl 9-fluorenyl chloroformate and 3-amino-1-propanol was as follows: 3-amino-1-propanol (300 mg, 4 mmol) was dissolved in anhydrous dichloromethane (15 mL) and the reaction mixture was cooled in an ice bath. A dichloromethane solution of chloroformic acid-9-fluorenylmethyl ester (528 mg, 2 mmol) was slowly added dropwise for 30 min. Subsequently, the reaction system was warmed up to room temperature and the reaction was continued with stirring for 1.5 hours. Upon completion of the reaction, the reaction mixture was washed three times with 0.5 M hydrochloric acid solution (5 mL x 3). The organic phase was washed once more with saturated saline (5 mL), dried over anhydrous sodium sulfate and filtered. The filtrate was concentrated under reduced pressure and the resulting residue was purified by rapid chromatography on silica gel (eluent: petroleum ether solution of 50% ethyl acetate) to afford the target product 3-(Fmoc-amino)-1-propanol (585 mg, 98%) as a white solid.
References
[1] Patent: CN107129455, 2017, A. Location in patent: Paragraph 0118; 0119; 0120; 0121
[2] Journal of Organic Chemistry, 2007, vol. 72, # 19, p. 7222 - 7228
[3] Synthesis, 1998, # 6, p. 859 - 866
[4] Nucleosides, Nucleotides and Nucleic Acids, 2000, vol. 19, # 8, p. 1301 - 1310
[5] Chinese Chemical Letters, 2012, vol. 23, # 8, p. 923 - 926
FMOC-BETA-ALANINOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from FMOC-BETA-ALANINOL manufacturers
- Product
- FMOC-BETA-ALANINOL 157887-82-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 96%-98%
- Supply Ability
- 10000KGS
- Release date
- 2019-12-26