ARG-GLU(EDANS)-(ASN670,LEU671)-APP770 (668-675)-LYS(DABCYL)-ARG

Product Name: ARG-GLU(EDANS)-(ASN670,LEU671)-APP770 (668-675)-LYS(DABCYL)-ARG
CAS No.: 310427-94-2
Chemical Name: ARG-GLU(EDANS)-(ASN670,LEU671)-APP770 (668-675)-LYS(DABCYL)-ARG
Synonyms: β-Secretase Substrate IV, Fluorogenic;Arg-Glu(Edans)-(Asn670, Leu671)-Amyloidb/A4 Protei;ARG-GLU(EDANS)-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-LYS(DABCYL)-ARG;ARG-GLU(EDANS)-(ASN670,LEU671)-APP770 (668-675)-LYS(DABCYL)-ARG;H-ARG-GLU(EDANS)-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-LYS(DABCYL)-ARG-OH;Arg-Glu: EDANS-: Asn670,Leu671-Amyloid b/A4 Protein Precursor770: 668-675-Lys: DABCYL-Arg;Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg;ARG-GLU(EDANS)-(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (668-675)-LYS (DABCYL)-ARG;Arg-Glu(EDANS)-[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 669-674-(DABCYL)Lys-Arg;ARG-GLU(EDANS)-[ASN670, LEU671]-AMYLOID B/A4 PROTEIN PRECURSOR 770 FRAGMENT 669-674-(DABCYL)LYS-ARG
CBNumber: CB7679456
Molecular Formula: C91H129N25O25S
Formula Weight: 2005.22
MOL File: 310427-94-2.mol

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ARG-GLU(EDANS)-(ASN670,LEU671)-APP770 (668-675)-LYS(DABCYL)-ARG Property

storage temp.: −20°C
solubility: DMSO: 5mg/mL
form: solid
color: red
Sequence: Arg-{Glu(EDANS)}-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-{Lys(DABCYL)}-Arg

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Safety

Safety Statements: 22-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 565758
Product name: β-Secretase Substrate IV, Fluorogenic
Purity: A highly sensitive fluorescence resonance energy transfer (FRET) peptide substrate, based on the EVNLDAEF sequence derived from the β-secretase site of the Swedish mutation of Amyloid Precursor
Packaging: 1 mg
Price: $246
Updated: 2025/07/31

Biosynth Carbosynth

Product number: FA110960
Product name: Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid beta/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt
Packaging: 250ug
Price: $175
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA110960
Product name: Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid beta/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt
Packaging: 500ug
Price: $300
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA110960
Product name: Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid beta/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt
Packaging: 1mg
Price: $525
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0000087
Product name: [ARG666, GLU667, ASN670, LEU671,LYS676, ARG677] - BETA- AMYLOID PRECURSOR PROTEIN(666-677), FRET, DABCYL/ EDANS LABELED
Purity: 95.00%
Packaging: 0.5MG
Price: $693
Updated: 2021/12/16

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ARG-GLU(EDANS)-(ASN670,LEU671)-APP770 (668-675)-LYS(DABCYL)-ARG Chemical Properties,Usage,Production

Uses

RE (EDANS) EVNLDAEFK (DABCYL) R is an EDANS and DABCYL double-labeled peptide，serves as a fluorescent substrate for BACE1(Em=360nm，Ex=528nm). RE (EDANS) EVNLDAEFK (DABCYL) R can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction[1].

Biological Activity

Cell permeable: no', 'Primary Target
β-secretase substrate', 'Product does not compete with ATP.', 'Reversible: no

References

[1] Ortega A, et.al. Synthesis and evaluation of arylquinones as BACE1 inhibitors, β-amyloid peptide aggregation inhibitors, and destabilizers of preformed β-amyloid fibrils. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2183-7. DOI:10.1016/j.bmcl.2011.03.023

ARG-GLU(EDANS)-(ASN670,LEU671)-APP770 (668-675)-LYS(DABCYL)-ARG Preparation Products And Raw materials

Raw materials

Preparation Products

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ARG-GLU(EDANS)-(ASN670,LEU671)-APP770 (668-675)-LYS(DABCYL)-ARG Suppliers

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310427-94-2, ARG-GLU(EDANS)-(ASN670,LEU671)-APP770 (668-675)-LYS(DABCYL)-ARGRelated Search:

ARG-GLU(EDANS)-(ASN670,LEU671)-APP770 (668-675)-LYS(DABCYL)-ARG H-LYS-ARG-OH

ARG-GLU(EDANS)-[ASN670, LEU671]-AMYLOID B/A4 PROTEIN PRECURSOR 770 FRAGMENT 669-674-(DABCYL)LYS-ARG

ARG-GLU(EDANS)-(ASN670,LEU671)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (668-675)-LYS (DABCYL)-ARG

ARG-GLU(EDANS)-(ASN670,LEU671)-APP770 (668-675)-LYS(DABCYL)-ARG

ARG-GLU(EDANS)-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-LYS(DABCYL)-ARG

Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid beta/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt

H-ARG-GLU(EDANS)-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-LYS(DABCYL)-ARG-OH

Arg-Glu(EDANS)-[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 669-674-(DABCYL)Lys-Arg

Arg-Glu: EDANS-: Asn670,Leu671-Amyloid b/A4 Protein Precursor770: 668-675-Lys: DABCYL-Arg

L-Arginine, L-arginyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-glutaminyl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-[4-[2-[4-(dimethylamino)phenyl]diazenyl]benzoyl]-L-lysyl-

L-Arginyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-L-glutaminyl-L-α-glutamyl-L-valyl-L-asparaginyl-L-leucyl-L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-N6-[4-[2-[4-(dimethylamino)phenyl]diazenyl]benzoyl]-L-lysyl-L-arginine

Arg-Glu(EDANS)-[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 669-674-(DABCYL)Lys-Arg

Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg

Arg-Glu(EDANS)-(Asn???,Leu??1)-Amyloid β/A4 Protein Precursor??? (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt

Arg-Glu(EDANS)-(Asn???,Leu???)-Amyloid β/A4 Protein Precursor??? (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt

β-Secretase Substrate IV, Fluorogenic

Arg-Glu(Edans)-(Asn670, Leu671)-Amyloidb/A4 Protei

310427-94-2

C91H129N25O25S

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