E-PHENYLETHENYLBORONIC ACID Property

Melting point:

146-156 °C(lit.)

Boiling point:

315.9±35.0 °C(Predicted)

Density 

1.130±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

form 

Powder and/or Chunks

pka

9.38±0.43(Predicted)

color 

Light yellow to beige

CAS DataBase Reference

6783-05-7(CAS DataBase Reference)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

37/39-26

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29310099

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

E-PHENYLETHENYLBORONIC ACID Chemical Properties,Usage,Production

Chemical Properties

Brown granular powder

Uses

trans-beta-Styrylboronic acid as reagent is used for palladium (Pd)-catalyzed Suzuki-Miyaura coupling reactions, diastereoselective synthesis via Pd-catalyzed Heck-Suzuki cascade reaction and rhodium (Rh)-catalyzed intramolecular amination of aryl azides. It is also used as reagent in preparation of optically active unsaturated amino acids by diastereoselective Petasis borono-Mannich reaction and amino alcohol dienes via Petasis 3-component reaction using Ru-catalyzed ring-closing metathesis and isomerization.

Uses

Reagent used for

• Palladium (Pd)-catalyzed Suzuki-Miyaura coupling reactions
• Rhodium (Rh)-catalyzed intramolecular amination of aryl azides
• Diastereoselective synthesis via Pd-catalyzed Heck-Suzuki cascade reaction
• Copper (Cu)-mediated cyanation
• Rhodium (Rh)-catalyzed asymmetric addition
• Diastereoselective synthesis via iridium (Ir)-catalyzed addition
• Palladium (Pd)-catalyzed cascade cyclization

• Optically active unsaturated amino acids by diastereoselective Petasis borono-Mannich reaction
• Amino alcohol dienes via Petasis 3-component reaction using Ru-catalyzed ring-closing metathesis and isomerization

Uses

E-Phenylethenylboronic acid is a reagent used for• ;Palladium (Pd)-catalyzed Suzuki-Miyaura coupling reactions
1 Rhodium (Rh)-catalyzed intramolecular amination of aryl azides
2 Diastereoselective synthesis via Pd-catalyzed Heck-Suzuki cascade reaction
3 Copper (Cu)-mediated cyanation
4 Rhodium (Rh)-catalyzed asymmetric addition
5 Diastereoselective synthesis via iridium (Ir)-catalyzed addition
6 Palladium (Pd)-catalyzed cascade cyclization
7 Reagent used in Preparation of • ;Optically active unsaturated amino acids by diastereoselective Petasis borono-Mannich reactio