ChemicalBook > CAS DataBase List > 2,5-Dimethylphenylboronic acid

2,5-Dimethylphenylboronic acid

Product Name
2,5-Dimethylphenylboronic acid
CAS No.
85199-06-0
Chemical Name
2,5-Dimethylphenylboronic acid
Synonyms
AKOS BRN-0066;AKOS BRN-0086;2-Borono-p-xylene;CHEMBRDG-BB 4003297;RARECHEM AH PB 0196;RARECHEM AH PB 0089;p-Xyleneboronic acid;P-XYLENE-2-BORONIC ACID;2,5-DIMETHYLPHENYLBORONIC ACID;2,5-DIMETHYLBENZENEBORONIC ACID
CBNumber
CB7696062
Molecular Formula
C8H11BO2
Formula Weight
149.98
MOL File
85199-06-0.mol
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2,5-Dimethylphenylboronic acid Property

Melting point:
186-191 °C (lit.)
Boiling point:
305.1±52.0 °C(Predicted)
Density 
1.07±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
8.70±0.58(Predicted)
form 
Solid
color 
White
BRN 
3241785
CAS DataBase Reference
85199-06-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-22
Safety Statements 
37/39-26-36/37
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
483516
Product name
2,5-Dimethylphenylboronic acid
Packaging
5g
Price
$107
Updated
2023/06/20
Sigma-Aldrich
Product number
483516
Product name
2,5-Dimethylphenylboronic acid
Packaging
25g
Price
$468
Updated
2023/06/20
TCI Chemical
Product number
D3517
Product name
2,5-Dimethylphenylboronic Acid (contains varying amounts of Anhydride)
Packaging
1g
Price
$20
Updated
2025/07/31
TCI Chemical
Product number
D3517
Product name
2,5-Dimethylphenylboronic Acid (contains varying amounts of Anhydride)
Packaging
5g
Price
$48
Updated
2025/07/31
TCI Chemical
Product number
D3517
Product name
2,5-Dimethylphenylboronic Acid (contains varying amounts of Anhydride)
Packaging
25g
Price
$213
Updated
2025/07/31
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2,5-Dimethylphenylboronic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

Reactant for:• ;Friedel-Crafts alkylation1• ;Suzuki-Miyaura coupling2

Uses

suzuki reaction

Uses

Reactant for:

  • Friedel-Crafts alkylation
  • Suzuki-Miyaura coupling

Synthesis

121-43-7

553-94-6

7732-18-5

85199-06-0

The general procedure for the synthesis of 2,5-dimethylphenylboronic acid from trimethyl borate, 2,5-dimethylbromobenzene and aqueous electrophoretic grade was as follows: 1-bromo-2,5-dimethylbenzene (25.0 g, 0.135 mol) was dissolved in 200 ml of tetrahydrofuran under the protection of nitrogen in a 1 L round-bottomed flask and cooled to -78 °C. A 1.6 M n-butyllithium solution was added slowly dropwise and the reaction was stirred for 2 hours keeping the temperature at -78 °C. Subsequently, trimethyl borate (18.2 g, 0.176 mol) was added dropwise and the reaction continued at the same temperature. After completion of the reaction, 1 equivalent of hydrochloric acid (101 ml, 0.162 mol) was added to acidify the reaction mixture at room temperature and stirred for 1 hour. The reaction solution was concentrated under reduced pressure and the resulting solid was recrystallized from hexane to give Intermediate 1-b (12.5 g, 62% yield).

References

[1] Patent: KR2015/52989, 2015, A. Location in patent: Paragraph 0326-0331

2,5-Dimethylphenylboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,5-Dimethylphenylboronic acid manufacturers

Career Henan Chemical Co
Product
2,5-Dimethylphenylboronic acid 85199-06-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg,5kg,100kg
Release date
2019-07-04

85199-06-0, 2,5-Dimethylphenylboronic acidRelated Search:

4-Trifluoromethylphenylboronic acid 4-Tolylboronic acid 4-Dimethylaminobenzaldehyde Folic acid Sodium xylenesulfonate Phenylboronic acid 3,5-Difluorophenylboronic acid Methyl 2,2-dimethylphenylacetate Ethyl 2-(Chlorosulfonyl)acetate Phenethylboronic acid Ascoric Acid 3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YLBORONIC ACID 4-Methoxy-2,5-dimethylphenylboronic acid 4-BROMO-2,5-DIMETHYLPHENYLBORONIC ACID 2,3,5,6-TETRAMETHYLPHENYLBORONIC ACID 2-Formyl-5-methylphenylboronic acid 3,5-Dimethylphenylboronic Acid (contains varying amounts of Anhydride),3,5-DIMETHYLPHENYLBORONIC ACID 4-Ethoxy-3,5-dimethylphenylboronic acid

  • P-XYLENE-2-BORONIC ACID
  • RARECHEM AH PB 0089
  • RARECHEM AH PB 0196
  • CHEMBRDG-BB 4003297
  • AKOS BRN-0086
  • Boronic acid, B-(2,5-dimethylphenyl)-
  • AKOS BRN-0066
  • 2,5-DIMETHYLPHENYLBORONIC ACID
  • 2,5-DIMETHYLBENZENEBORONIC ACID
  • 2,5-Dimethylbenzeneboronic acid 97%
  • 3-(Morpholino)phenylboronic acid HCl
  • 2,5-Dimethylphenylboronic Acid (contains varying amounts of Anhydride)
  • 2,5-Dimethylphenylboronic acid ,98%
  • (2,5-dimethylphenyl)boronic acid(SALTDATA: FREE)
  • p-Xyleneboronic acid
  • 2-Borono-p-xylene
  • 2,5-Dimethylbenzeneboronic Acid p-Xylene-2-boronic Acid
  • B-(2,5-dimethylphenyl)-Boronicacid
  • 2,5-Dimethylphenylboronic acid - [D2940]
  • 85199-06-0
  • CH32C6H3BOH2
  • BORONIC ACID
  • Boronic Acids and Derivatives
  • Aryl
  • Organometallic Reagents
  • B (Classes of Boron Compounds)
  • Boronic Acids
  • Boronate Ester
  • Potassium Trifluoroborate
  • Aryl Boronic Acids
  • Boronic Acids and Derivatives
  • Chemical Synthesis
  • Disubstituted Aryl Boronic Acids
  • Organometallic Reagents
  • Heterocyclic Compounds
  • Boronic Acid
  • blocks
  • BoronicAcids
  • Boric Acid
  • Boronic Acids
  • Boronic Acids and Derivatives
  • B (Classes of Boron Compounds)
  • Boronic Acids
  • Aryl
  • Organoborons