ChemicalBook > CAS DataBase List > 4-(2-Aminoethyl)-1-Boc-piperidine

4-(2-Aminoethyl)-1-Boc-piperidine

Product Name
4-(2-Aminoethyl)-1-Boc-piperidine
CAS No.
146093-46-1
Chemical Name
4-(2-Aminoethyl)-1-Boc-piperidine
Synonyms
tert-butyl 4-(2-aminoethyl)piperidine-1-carboxylate;4-(AMINOETHYL)-1-BOC-PIPERIDINE;1-N-Boc-4-(Aminoethyl)-piperidine;4-(2-AMINOETHYL)-1-BOC-PIPERIDINE;4-(AMINOETHYL)-1-N-BOC-PIPERIDINE;4-(2-Aminoethyl)-1-N-Boc-piperidine;4-(Aminoethyl)-1-N-Boc-piperidine Hcl;4-(Aminoethyl)-1-N-Boc-piperidine;4-(2-Aminoethyl)piperidine, N1-BOC protected;4-(Aminoethyl)-1-N-Boc-piperidine - [A13695]
CBNumber
CB7698541
Molecular Formula
C12H24N2O2
Formula Weight
228.33
MOL File
146093-46-1.mol
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4-(2-Aminoethyl)-1-Boc-piperidine Property

Boiling point:
316.0±15.0 °C(Predicted)
Density 
1.010±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
semisolid
pka
10.43±0.10(Predicted)
color 
off-white to light yellow
InChI
InChI=1S/C12H24N2O2/c1-12(2,3)16-11(15)14-8-5-10(4-7-13)6-9-14/h10H,4-9,13H2,1-3H3
InChIKey
LBQDLHPFISVBRU-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC(CCN)CC1
CAS DataBase Reference
146093-46-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36/37/39
RIDADR 
UN2811
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A608030
Product name
4-(2-Aminoethyl)-1-boc-piperidine
Packaging
1g
Price
$105
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB139873
Product name
tert-Butyl 4-(2-aminoethyl)piperidine-1-carboxylate
Packaging
100mg
Price
$50
Updated
2021/12/16
Synthonix
Product number
A13695
Product name
4-(Aminoethyl)-1-N-Boc-piperidine
Purity
95+%
Packaging
1g
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB139873
Product name
tert-Butyl 4-(2-aminoethyl)piperidine-1-carboxylate
Packaging
250mg
Price
$80
Updated
2021/12/16
AK Scientific
Product number
W3189
Product name
tert-Butyl4-(2-aminoethyl)piperidine-1-carboxylate
Packaging
1g
Price
$105
Updated
2021/12/16
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4-(2-Aminoethyl)-1-Boc-piperidine Chemical Properties,Usage,Production

Synthesis

256411-39-9

146093-46-1

General procedure for the synthesis of 2-(N-Boc-4-piperidinyl)ethylamine from 1-Boc-4-(cyanomethyl)piperidine: tert-butyl 4-(cyanomethyl)piperidine-1-carboxylate (20 g, 89.29 mmol) and NH4OH (9 mL) were dissolved in methanol (200 mL) and Raney Ni (6 g, 101.69 mmol) was added. The reaction was carried out at 50°C for 5 h under H2 pressure of 50 psi. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filtrate was concentrated to afford the target product 2-(N-Boc-4-piperidinyl)ethylamine (20.5 g, 100%) as a colorless oil.1H NMR (400 MHz, CDCl3) δ 1.06-1.19 (m, 2H), 1.44 (d, J = 7.41 Hz, 2H), 1.47 (s 9H), 1.50-1.58 (m, 1H), 1.66 (d, J = 12.49 Hz, 2H), 2.09 (br.s., 2H), 2.70 (t, J = 12.29 Hz, 2H), 2.75-2.83 (m, 2H), 4.08 (br.s., 2H).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 21, p. 4805 - 4811

4-(2-Aminoethyl)-1-Boc-piperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-Aminoethyl)-1-Boc-piperidine Suppliers

Porse Fine Chemical Co.,LTD
Tel
20-66003216 18666003216
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+86-20-28069063
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info@porsefinechemical.com
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China
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
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China
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35896
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Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
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China
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Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
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sales@chemreagents.com
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United States
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Shanghai Boc Chemical Co.,Ltd
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021-34975603-808 18721111801
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+86-21-34975602-805
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sales@bocpharma.com
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China
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1009
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Nanjing Chemlin Chemical Co., Ltd
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025-83697070
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+86-25-83453306
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info@chemlin.com.cn
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China
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15883
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64
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
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028-85114309 18982182443
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yangli@happysyn.com
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China
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2150
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55
Shanghai Topbiochem Technology Co., Ltd
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+86-21-60341587
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+86-21-61294319
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sales@topbiochem.com
Country
China
ProdList
6175
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View Lastest Price from 4-(2-Aminoethyl)-1-Boc-piperidine manufacturers

Career Henan Chemical Co
Product
4-(2-Aminoethyl)-1-Boc-piperidine 146093-46-1
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2018-12-25

146093-46-1, 4-(2-Aminoethyl)-1-Boc-piperidineRelated Search:


  • 4-(AMINOETHYL)-1-BOC-PIPERIDINE
  • 4-(AMINOETHYL)-1-N-BOC-PIPERIDINE
  • 4-(2-Aminoethyl)-1-N-Boc-piperidine
  • tert-butyl 4-(2-aminoethyl)piperidine-1-carboxylate
  • 1-N-Boc-4-(Aminoethyl)-piperidine
  • 1-Piperidinecarboxylic acid, 4-(2-aminoethyl)-, 1,1-dimethylethyl ester
  • 4-(Aminoethyl)-1-N-Boc-piperidine Hcl
  • 4-(AMinoethyl)-1-N-Boc-piperidine/tert-butyl 4-(2-aMinoethyl)piperidine-1-carboxylate
  • 4-(2-AMINO-ETHYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • 4-(2-AMINOETHYL)-1-BOC-PIPERIDINE
  • 4-(2-Aminoethyl)piperidine, N1-BOC protected
  • 4-(2-Aminoethyl)piperidin-1-carboxylic acid tert-butyl ester
  • 4-(2-aminoethyl)-1-piperidinecarboxylic acid tert-butyl ester
  • 4-(Aminoethyl)-1-<i>N</i>-Boc-piperidine
  • 4-(Aminoethyl)-1-N-Boc-piperidine - [A13695]
  • tert-Butyl 4-(2-aminoethyl)piperidin-1-carboxylate
  • 146093-46-1
  • pharmacetical