RUGULOSIN

Product Name: RUGULOSIN
CAS No.: 23537-16-8
Chemical Name: RUGULOSIN
Synonyms: RUGULOSIN;Nsc160880;NSC 249990;Rugulosin A;(+)-Rugulosin;(+)-RUGULOSIN;(+)-(1S,1'S,2R,2'R,3S,3'S,9AR,9'AR)-RUGULOSIN;Rugulosin ((+)-Rugulosin), RNA polymerase inhibitor;(+)-Rugulosin, (1S,1S,2R,2R,3S,3S,9aR,9aR)-Rugulosin, (2R,2R)-Rugulosin;5H,6H-6,13A,5A,14-[1,2,3,4]Butanetetraylcycloocta[1,2-B:5,6-B']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-
CBNumber: CB7701377
Molecular Formula: C30H22O10
Formula Weight: 542.49
MOL File: 23537-16-8.mol

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RUGULOSIN Property

Melting point:: 293℃ (decomposition)
Boiling point:: 535.95°C (rough estimate)
Density: 1.3164 (rough estimate)
refractive index: 1.5376 (estimate)
storage temp.: Store at -20°C
solubility: DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form: A solid
pka: 4.20±1.00(Predicted)
IARC: 3 (Vol. 40, Sup 7) 1987
EPA Substance Registry System: 5H,6H-6,13a,5a,14-[1,2,3,4]Butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, (5aS,6R,13aS,14R,17S,18R,19R,20S)- (23537-16-8)

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Safety

HS Code: 29419000

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 23558
Product name: (+)-Rugulosin
Purity: ≥98%
Packaging: 1mg
Price: $153
Updated: 2024/03/01

Usbiological

Product number: 045263
Product name: Rugulosin
Packaging: 250ug
Price: $286
Updated: 2021/12/16

Usbiological

Product number: R9908
Product name: Rugulosin
Packaging: 1mg
Price: $482
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0004344
Product name: RUGULOSIN
Purity: 95.00%
Packaging: 5MG
Price: $502.17
Updated: 2021/12/16

Adipogen Life Sciences

Product number: AG-CN2-0124-C250
Product name: Rugulosin
Purity: ≥95%(HPLC)
Packaging: 250μg
Price: $45
Updated: 2021/12/16

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RUGULOSIN Chemical Properties,Usage,Production

Description

(+)-Rugulosin is a pigment and mycotoxin produced by certain fungi. It inhibits HIV-1 integrase activity with IC₅₀ values of 19 and 25 μM in coupled and strand transfer assays, respectively. It also inhibits ribonuclease H in rat liver by 83% at a concentration of 157 μM and ribonucleases H1, H2, and H3 in T. pyriformis by 100, 99, and 100%, respectively, at a concentration of 313 μM. (+)-Rugulosin leads to hepatic injury and liver cell hyperplasia in mice when administered in the diet. It is cytotoxic to insect cells but not mammalian C6/36, L929, and HepG2 cells (ID₅₀s = 1.2, >200, 23.7, and >200 μg/ml, respectively).

Uses

(+)-Rugulosin is an intense yellow pigment produced by some species of Penicillium, Aspergillus and the fungal symbiotants of some lichens. (+)-Rugulosin shows antibacterial and insecticidal activity and has found application as a bioinsecticide, notably as the active secondary metabolite in endophytic fungi of seedlings.

Uses

Rugulosin (+ form) is an intense yellow pigment produced by Penicillium and Aspergillus.

Definition

ChEBI: Rugulosin is a cyclic ketone and an organic polycyclic compound.

RUGULOSIN Preparation Products And Raw materials

Raw materials

Preparation Products

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RUGULOSIN Suppliers

China 19 Germany 2 United Kingdom 3 United States 8 Global 32

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Lynnchem

Tel: 86-(0)29-85992781 17792393971
Email: info@lynnchem.com
Country: China
ProdList: 4587
Advantage: 58

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57423
Advantage: 58

BOC Sciences

Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Country: United States
ProdList: 19741
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Meng Cheng Technology (Shanghai) Co., LTD

Tel: 400-820-6829
Email: sales@mitachieve.com
Country: China
ProdList: 8860
Advantage: 58

Zhejiang Huida Biotech Co., LTD

Tel: 0571-89903882 13626641628
Email: jiangnan@huidabiotech.com
Country: China
ProdList: 3656
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44807
Advantage: 58

23537-16-8, RUGULOSINRelated Search:

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(+)-RUGULOSIN

RUGULOSIN

(+)-(1S,1'S,2R,2'R,3S,3'S,9AR,9'AR)-RUGULOSIN

(+)-Rugulosin, (1S,1S,2R,2R,3S,3S,9aR,9aR)-Rugulosin, (2R,2R)-Rugulosin

5H,6H-6,13A,5A,14-[1,2,3,4]Butanetetraylcycloocta[1,2-B:5,6-B']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-

5H,6H-6,13A,5A,14-[1,2,3,4]Butanetetraylcycloocta[1,2-B:5,6-B']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, [5as-(5ar*,6S*,13ar*,14S*,17R*,18S*,19S*,20R*)]-

Nsc160880

NSC 249990

Rugulosin A

5H,6H-6,13a,5a,14-[1,2,3,4]Butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, (5aS,6R,13aS,14R,17S,18R,19R,20S)-

(+)-Rugulosin

Rugulosin ((+)-Rugulosin), RNA polymerase inhibitor

23537-16-8

Antibiotic