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RUGULOSIN

Product Name
RUGULOSIN
CAS No.
23537-16-8
Chemical Name
RUGULOSIN
Synonyms
RUGULOSIN;Nsc160880;NSC 249990;Rugulosin A;(+)-Rugulosin;(+)-RUGULOSIN;(+)-(1S,1'S,2R,2'R,3S,3'S,9AR,9'AR)-RUGULOSIN;(+)-Rugulosin, (1S,1S,2R,2R,3S,3S,9aR,9aR)-Rugulosin, (2R,2R)-Rugulosin;5H,6H-6,13A,5A,14-[1,2,3,4]Butanetetraylcycloocta[1,2-B:5,6-B']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-;5H,6H-6,13a,5a,14-[1,2,3,4]Butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, (5aS,6R,13aS,14R,17S,18R,19R,20S)-
CBNumber
CB7701377
Molecular Formula
C30H22O10
Formula Weight
542.49
MOL File
23537-16-8.mol
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RUGULOSIN Property

Melting point:
293℃ (decomposition)
Boiling point:
535.95°C (rough estimate)
Density 
1.3164 (rough estimate)
refractive index 
1.5376 (estimate)
storage temp. 
Store at -20°C
solubility 
DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form 
A solid
pka
4.20±1.00(Predicted)
IARC
3 (Vol. 40, Sup 7) 1987
EPA Substance Registry System
5H,6H-6,13a,5a,14-[1,2,3,4]Butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, (5aS,6R,13aS,14R,17S,18R,19R,20S)- (23537-16-8)
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Safety

HS Code 
29419000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23558
Product name
(+)-Rugulosin
Purity
≥98%
Packaging
1mg
Price
$153
Updated
2024/03/01
Usbiological
Product number
045263
Product name
Rugulosin
Packaging
250ug
Price
$286
Updated
2021/12/16
Usbiological
Product number
R9908
Product name
Rugulosin
Packaging
1mg
Price
$482
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0004344
Product name
RUGULOSIN
Purity
95.00%
Packaging
5MG
Price
$502.17
Updated
2021/12/16
Adipogen Life Sciences
Product number
AG-CN2-0124-C250
Product name
Rugulosin
Purity
≥95%(HPLC)
Packaging
250μg
Price
$45
Updated
2021/12/16
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RUGULOSIN Chemical Properties,Usage,Production

Description

(+)-Rugulosin is a pigment and mycotoxin produced by certain fungi. It inhibits HIV-1 integrase activity with IC50 values of 19 and 25 μM in coupled and strand transfer assays, respectively. It also inhibits ribonuclease H in rat liver by 83% at a concentration of 157 μM and ribonucleases H1, H2, and H3 in T. pyriformis by 100, 99, and 100%, respectively, at a concentration of 313 μM. (+)-Rugulosin leads to hepatic injury and liver cell hyperplasia in mice when administered in the diet. It is cytotoxic to insect cells but not mammalian C6/36, L929, and HepG2 cells (ID50s = 1.2, >200, 23.7, and >200 μg/ml, respectively).

Uses

(+)-Rugulosin is an intense yellow pigment produced by some species of Penicillium, Aspergillus and the fungal symbiotants of some lichens. (+)-Rugulosin shows antibacterial and insecticidal activity and has found application as a bioinsecticide, notably as the active secondary metabolite in endophytic fungi of seedlings.

Uses

Rugulosin (+ form) is an intense yellow pigment produced by Penicillium and Aspergillus.

Definition

ChEBI: Rugulosin is a cyclic ketone and an organic polycyclic compound.

RUGULOSIN Preparation Products And Raw materials

Raw materials

Preparation Products

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RUGULOSIN Suppliers

Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
ProdList
4587
Advantage
58
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
55827
Advantage
58
BOC Sciences
Tel
+16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19743
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58
Meng Cheng Technology (Shanghai) Co., LTD
Tel
400-820-6829
Email
sales@mitachieve.com
Country
China
ProdList
8864
Advantage
58
Zhejiang Huida Biotech Co., LTD
Tel
0571-89903882 13626641628
Email
jiangnan@huidabiotech.com
Country
China
ProdList
3661
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58

23537-16-8, RUGULOSINRelated Search:


  • (+)-RUGULOSIN
  • RUGULOSIN
  • (+)-(1S,1'S,2R,2'R,3S,3'S,9AR,9'AR)-RUGULOSIN
  • (+)-Rugulosin, (1S,1S,2R,2R,3S,3S,9aR,9aR)-Rugulosin, (2R,2R)-Rugulosin
  • 5H,6H-6,13A,5A,14-[1,2,3,4]Butanetetraylcycloocta[1,2-B:5,6-B']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-
  • 5H,6H-6,13A,5A,14-[1,2,3,4]Butanetetraylcycloocta[1,2-B:5,6-B']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, [5as-(5ar*,6S*,13ar*,14S*,17R*,18S*,19S*,20R*)]-
  • Nsc160880
  • NSC 249990
  • Rugulosin A
  • 5H,6H-6,13a,5a,14-[1,2,3,4]Butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, (5aS,6R,13aS,14R,17S,18R,19R,20S)-
  • (+)-Rugulosin
  • 23537-16-8
  • Antibiotic