ChemicalBook > CAS DataBase List > RUGULOSIN
RUGULOSIN
- Product Name
- RUGULOSIN
- CAS No.
- 23537-16-8
- Chemical Name
- RUGULOSIN
- Synonyms
- RUGULOSIN;Nsc160880;NSC 249990;Rugulosin A;(+)-Rugulosin;(+)-RUGULOSIN;(+)-(1S,1'S,2R,2'R,3S,3'S,9AR,9'AR)-RUGULOSIN;(+)-Rugulosin, (1S,1S,2R,2R,3S,3S,9aR,9aR)-Rugulosin, (2R,2R)-Rugulosin;5H,6H-6,13A,5A,14-[1,2,3,4]Butanetetraylcycloocta[1,2-B:5,6-B']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-;5H,6H-6,13a,5a,14-[1,2,3,4]Butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, (5aS,6R,13aS,14R,17S,18R,19R,20S)-
- CBNumber
- CB7701377
- Molecular Formula
- C30H22O10
- Formula Weight
- 542.49
- MOL File
- 23537-16-8.mol
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RUGULOSIN Property
- Melting point:
- 293℃ (decomposition)
- Boiling point:
- 535.95°C (rough estimate)
- Density
- 1.3164 (rough estimate)
- refractive index
- 1.5376 (estimate)
- storage temp.
- Store at -20°C
- solubility
- DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- form
- A solid
- pka
- 4.20±1.00(Predicted)
- IARC
- 3 (Vol. 40, Sup 7) 1987
- EPA Substance Registry System
- 5H,6H-6,13a,5a,14-[1,2,3,4]Butanetetraylcycloocta[1,2-b:5,6-b']dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, (5aS,6R,13aS,14R,17S,18R,19R,20S)- (23537-16-8)
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Safety
- HS Code
- 29419000
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 23558
- Product name
- (+)-Rugulosin
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $153
- Updated
- 2024/03/01
Usbiological
- Product number
- 045263
- Product name
- Rugulosin
- Packaging
- 250ug
- Price
- $286
- Updated
- 2021/12/16
Usbiological
- Product number
- R9908
- Product name
- Rugulosin
- Packaging
- 1mg
- Price
- $482
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- INB0004344
- Product name
- RUGULOSIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.17
- Updated
- 2021/12/16
Adipogen Life Sciences
- Product number
- AG-CN2-0124-C250
- Product name
- Rugulosin
- Purity
- ≥95%(HPLC)
- Packaging
- 250μg
- Price
- $45
- Updated
- 2021/12/16
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RUGULOSIN Chemical Properties,Usage,Production
Description
(+)-Rugulosin is a pigment and mycotoxin produced by certain fungi. It inhibits HIV-1 integrase activity with IC50 values of 19 and 25 μM in coupled and strand transfer assays, respectively. It also inhibits ribonuclease H in rat liver by 83% at a concentration of 157 μM and ribonucleases H1, H2, and H3 in T. pyriformis by 100, 99, and 100%, respectively, at a concentration of 313 μM. (+)-Rugulosin leads to hepatic injury and liver cell hyperplasia in mice when administered in the diet. It is cytotoxic to insect cells but not mammalian C6/36, L929, and HepG2 cells (ID50s = 1.2, >200, 23.7, and >200 μg/ml, respectively).
Uses
(+)-Rugulosin is an intense yellow pigment produced by some species of Penicillium, Aspergillus and the fungal symbiotants of some lichens. (+)-Rugulosin shows antibacterial and insecticidal activity and has found application as a bioinsecticide, notably as the active secondary metabolite in endophytic fungi of seedlings.
Uses
Rugulosin (+ form) is an intense yellow pigment produced by Penicillium and Aspergillus.
Definition
ChEBI: Rugulosin is a cyclic ketone and an organic polycyclic compound.
RUGULOSIN Preparation Products And Raw materials
Raw materials
Preparation Products
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