ChemicalBook > CAS DataBase List > NEUROPEPTIDE Y (13-36), HUMAN, RAT

NEUROPEPTIDE Y (13-36), HUMAN, RAT

Product Name
NEUROPEPTIDE Y (13-36), HUMAN, RAT
CAS No.
122341-40-6
Chemical Name
NEUROPEPTIDE Y (13-36), HUMAN, RAT
Synonyms
NPY (13-36) (HUMAN, RAT);Neuropeptide Y(13-36)【rat】;13-36-Human neuropeptide Y;NEUROPEPTIDE Y (13-36) HUMAN;PAEDMARYYSALRHYINLITRQRY-NH2;NEUROPEPTIDE Y (13-36), HUMAN, RAT;13-36-Neuropeptide Y (human) (9CI);Neuropeptide Y (13-36), amide, human;PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2;H-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2
CBNumber
CB7703700
Molecular Formula
C134H207N41O36S
Formula Weight
3000.4
MOL File
122341-40-6.mol
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NEUROPEPTIDE Y (13-36), HUMAN, RAT Property

Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
-15°C
solubility 
Soluble in DMSO
form 
Solid
color 
White to off-white
Sequence
Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0044417
Product name
NeuropeptideY(13-36),amide,human
Packaging
500ug
Price
$160
Updated
2021/12/16
ChemScene
Product number
CS-0044417
Product name
NeuropeptideY(13-36),amide,human
Packaging
1mg
Price
$260
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0002618
Product name
NEUROPEPTIDE Y (13-36), HUMAN
Purity
95.00%
Packaging
0.5MG
Price
$601.76
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0002618
Product name
NEUROPEPTIDE Y (13-36), HUMAN
Purity
95.00%
Packaging
1MG
Price
$697.34
Updated
2021/12/16
ChemScene
Product number
CS-0044417
Product name
NeuropeptideY(13-36),amide,human
Packaging
5mg
Price
$780
Updated
2021/12/16
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NEUROPEPTIDE Y (13-36), HUMAN, RAT Chemical Properties,Usage,Production

Uses

Neuropeptide Y (13-36), amide, human is a selective?neuropeptide Y2 receptor?agonist[1].

in vivo

Neuropeptide Y (13-36) (intraventricular injection; 25-3000 pmol) produces a dose-dependent increase (up to 14%; ED50 value of 0.3 nmol for overall effects and 0.97 nmol for the peak effects) in mean arterial blood pressure in the awake, unrestrained male rat without affecting heart rate. Central administration of porcine Neuropeptide Y (13-36) produces marked vasodepressor and bradycardic actions in the anaesthetized α-chloralose and in the awake unrestrained male rat[1].Neuropeptide Y (13-36) (intracerebroventricular injection; 50 ng; alone; injected 30 and 15 min before measurements) injected into na?ve mice impairs social novelty preference, but not sociability, and this effect is inhibited by the NPY Y2 receptor antagonist BIIE 0246[2].

Animal Model:Male ICR mice (age 4-7 weeks)[2]
Dosage:50 ng/mouse
Administration:Intracerebroventricular injection
Result:Significantly decreased interaction time with the new stranger mouse in session 3 that NPY 13-36.

IC 50

NPY Y2 receptor

References

[1] Aguirre JA, et al. Centrally injected neuropeptide Y (13-36) produces vasopressor effects and antagonizes the vasodepressor action of neuropeptide Y (1-36) in the awake male rat. Neurosci Lett. 1990 Oct 2;118(1):5-8. DOI:10.1016/0304-3940(90)90235-2
[2] Daiki Ueda, et al. Increase in neuropeptide Y activity impairs social behaviour in association with glutamatergic dysregulation in diabetic mice. Br J Pharmacol. 2021 Feb;178(3):726-740. DOI:10.1111/bph.15326

NEUROPEPTIDE Y (13-36), HUMAN, RAT Preparation Products And Raw materials

Raw materials

Preparation Products

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NEUROPEPTIDE Y (13-36), HUMAN, RAT Suppliers

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View Lastest Price from NEUROPEPTIDE Y (13-36), HUMAN, RAT manufacturers

Career Henan Chemical Co
Product
NEUROPEPTIDE Y (13-36), HUMAN, RAT 122341-40-6
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-13

122341-40-6, NEUROPEPTIDE Y (13-36), HUMAN, RATRelated Search:


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