METHYL-D3-MALONIC ACID

Product Name: METHYL-D3-MALONIC ACID
CAS No.: 42522-59-8
Chemical Name: METHYL-D3-MALONIC ACID
Synonyms: NSC 2520-d3;Isosuccinic Acid-d3;MethylMalonic Acid-d3;METHYL-D3-MALONIC ACID;Methyl-d?-malonic acid;[2H3]-Methylmalonic Acid;Methyl-d3-propanedioic Acid;2-Methylpropanedioic acid D3;2-METHYL-D3-PROPANEDIOIC ACID;1,1-Ethanedicarboxylic Acid-d3
CBNumber: CB7715949
Molecular Formula: C4H3D3O4
Formula Weight: 121.11
MOL File: 42522-59-8.mol

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METHYL-D3-MALONIC ACID Property

Melting point:: 134-136 °C(lit.)
Flash point:: 2 °C
storage temp.: -20°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White

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Safety

Hazard Codes: Xn,F
Risk Statements: 20/22-36/37/38-36-20/21/22-11
Safety Statements: 26-36-36/37-16
RIDADR: UN 1648 3 / PGII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M-105
Product name: Methyl-D3-malonic acid solution
Purity: 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1mL
Price: $180
Updated: 2024/03/01

Sigma-Aldrich

Product number: 490318
Product name: Methyl-d3-malonic acid
Purity: 98 atom % D
Packaging: 250mg
Price: $820
Updated: 2024/03/01

TRC

Product number: M318862
Product name: MethylmalonicAcid-d3
Packaging: 10mg
Price: $120
Updated: 2021/12/16

Usbiological

Product number: 017011
Product name: Methylmalonic Acid-d3
Packaging: 10mg
Price: $382
Updated: 2021/12/16

IsoSciences

Product number: 13018
Product name: Methyl-d3-malonic acid
Purity: ≥95%
Packaging: 1mg
Price: $109
Updated: 2021/12/16

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METHYL-D3-MALONIC ACID Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Solid

Uses

An isotope labelled derivative of Methylmalonic Acid (M318860), binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.

Uses

Methyl-d3-malonic acid is an isotope labelled derivative of Methylmalonic Acid (M318860), binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-depend ent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.

General Description

Methylmalonic acid, a malonic acid derivative, is a vital intermediate in the metabolism of fat and proteins and plays a key role in energy metabolism. Elevated methylmalonic acid levels can be caused by an inborn error of metabolism leading to methylmalonic aciduria or indicate early vitamin B<sub>12</sub> deficiency. This internal standard is suitable for quantitation of methylmalonic acid levels by LC/MS or GC/MS in newborn screening and clinical testing applications to test for methylmalonic acidemia and diagnose vitamin B<sub>12</sub> deficiency.

METHYL-D3-MALONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL-D3-MALONIC ACID Suppliers

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42522-59-8, METHYL-D3-MALONIC ACIDRelated Search:

Dimethyl (2-methylbutyl)malonate, 97% Diisopropyl malonate Diethyl ethyl(isoamyl)malonate DIETHYL METHYL PROPYL MALONATE Diethyl isoamylmalonate Diethyl ethyl(1-methylbutyl)malonate METHYL-D3-MALONIC ACID UV-144 BIS(TRIMETHYLSILYL) MALONATE Diethyl ethyl(1-methylpropyl)malonate ETHYL TRIMETHYLSILYL MALONATE Malonic acid 2-METHYL-D3-PROPIONIC ACID Diethyl Methyl-D3-malonate DIETHYL 2-METHYL-D3-2-PROPYLMALONATE PROPIONIC-3,3,3-D3 ACID 2-METHYL-D3-PROPYL ALCOHOL PROPYL-3,3,3-D3 ALCOHOL

METHYL-D3-MALONIC ACID, 98 ATOM % D

METHYLMALONIC ACID (METHYL-D3)

METHYL-D3-MALONIC ACID

2-METHYL-D3-PROPANEDIOIC ACID

1,1-Ethanedicarboxylic Acid-d3

Isosuccinic Acid-d3

Methyl-d3-propanedioic Acid

NSC 2520-d3

Methyl-D3-malonic acid solution

MethylMalonic Acid-d3

2-Methylpropanedioic acid D3

Methylmalonic Acid-[d3] (Solution)

[2H3]-Methylmalonic Acid

2-(trideuteriomethyl)propanedioic acid

Methyl-d?-malonic acid

Methyl-d3-malonic acid in methanol

42522-59-8

CD3CHCO2H2

C4H3D3O4

CD3CHCOOH2

Stable Isotopes

BioChemical

Alphabetical Listings

M

Stable Isotopes

Aliphatics

Intermediates & Fine Chemicals

Isotope Labelled Compounds

Metabolites & Impurities

Pharmaceuticals