ChemicalBook > CAS DataBase List > 4-(4-Methoxyphenyl)-2-butanone

4-(4-Methoxyphenyl)-2-butanone

Product Name
4-(4-Methoxyphenyl)-2-butanone
CAS No.
104-20-1
Chemical Name
4-(4-Methoxyphenyl)-2-butanone
Synonyms
4-(4-METHOXYPHENYL)BUTAN-2-ONE;ANISYLACETONE;PARA ANISYL ACETONE;p-Methoxybenzylacetone;4-(P-METHOXYPHENYL)-2-BUTANONE;ANISALACETONE;METHOXY PHENYL BUTANONE;Raspberry ketone methyl ether;1-(4-METHOXYPHENYL)-3-BUTANONE;2-Butanone, 4-(4-methoxyphenyl)-
CBNumber
CB7731013
Molecular Formula
C11H14O2
Formula Weight
178.23
MOL File
104-20-1.mol
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4-(4-Methoxyphenyl)-2-butanone Property

Melting point:
8 °C (lit.)
Boiling point:
152-153 °C/15 mmHg (lit.)
Density 
1.046 g/mL at 25 °C (lit.)
vapor pressure 
9-2000Pa at 20-115℃
FEMA 
2672 | 4-(P-METHOXYPHENYL)-2-BUTANONE
refractive index 
n20/D 1.519(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Oil
color 
A colourless oily liquid with a sweet floral odour
Odor
at 100.00 %. sweet dried raspberry rose cherry fruity cassie absolute
Odor Type
berry
Water Solubility 
Not miscible in water.
JECFA Number
818
BRN 
1869592
LogP
2 at 23.1℃
CAS DataBase Reference
104-20-1(CAS DataBase Reference)
NIST Chemistry Reference
2-Butanone, 4-(4-methoxyphenyl)-(104-20-1)
EPA Substance Registry System
2-Butanone, 4-(4-methoxyphenyl)- (104-20-1)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
23-24/25
WGK Germany 
2
RTECS 
EL9085500
TSCA 
Yes
HS Code 
29145090
Toxicity
Both the acute oral LD50 value in rats and the acute dermal LD50 value in rabbits exceeded 5 g/kg (Russell, 1973)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P233Keep container tightly closed.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304IF INHALED:

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.

P362Take off contaminated clothing and wash before reuse.

P403Store in a well-ventilated place.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W267201
Product name
4-(4-Methoxyphenyl)-2-butanone
Purity
≥98%, FCC, FG
Packaging
sample-k
Price
$54.6
Updated
2024/03/01
Sigma-Aldrich
Product number
W267201
Product name
4-(4-Methoxyphenyl)-2-butanone
Purity
≥98%, FCC, FG
Packaging
100g
Price
$59.1
Updated
2024/03/01
Sigma-Aldrich
Product number
W267201
Product name
4-(4-Methoxyphenyl)-2-butanone
Purity
≥98%, FCC, FG
Packaging
1kg
Price
$99.6
Updated
2024/03/01
Sigma-Aldrich
Product number
W267201
Product name
4-(4-Methoxyphenyl)-2-butanone
Purity
≥98%, FCC, FG
Packaging
5kg
Price
$424
Updated
2024/03/01
Sigma-Aldrich
Product number
M19600
Product name
4-(4-Methoxyphenyl)-2-butanone
Purity
98%
Packaging
10g
Price
$16.74
Updated
2024/03/01
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4-(4-Methoxyphenyl)-2-butanone Chemical Properties,Usage,Production

Description

4-(p-Methoxyphenyl)-2-butanone has an intensely sweet, floral, fruity odor and a cherry-raspberry flavor at low concentrations. May be prepared by condensing acetone with anisaldehyde to yield anisylidene acetone and subsequent hydrogenation in the presence of Pd catalyst.

Chemical Properties

4-(p-Methoxyphenyl)-2-butanone has an intensely sweet, floral,fruity odor and cherry–raspberry flavor at low concentrations.

Chemical Properties

4-(4-Methoxyphenyl)-2-butanone is a clear colourless to pale yellow liquid. B.P. 277℃. Solidifies in the cold, melts again at 10℃. Very slightly soluble in water, soluble in alcohol and oils, poorly soluble in Propylene glycol. Intensely sweet, floral and slightly fruity, Cherry-preserve-like odor of good tenacity. It has considerable resemblance to Heliotropine in its overall performance in a composition. Pleasant, sweet-fruity, Cherry-Raspberry-type flavor at concentrations below 40 ppm. Tends to appear "perfumey" at levels higher than 100 ppm.

Occurrence

Contained (approximately 53% level) in the odorous principle obtained by extraction and hydrolysis from aloe wood (Aquilaria algallocha Roxb.) and in anise.

Uses

4-(4-Methoxyphenyl)-2-butanone is used as pharmaceutical intermediate.

Uses

4-(4-Methoxyphenyl)-2-butanone is used in insect attractants, organic synthesis, flavoring. This ketone, a methylether of a very popular material (see para-Hydroxy phenylbutanone), finds use in perfume compositions as a modifier for Heliotropine, a sweetener for Cyclamen aldehyde, and a blender in many types of sweet florals, Fougeres, Oriental fragrances, etc. It suffers from the drawback of being considerably more expensive than Heliotropine, and it can therefore not truly be classified as a substitute for that material. It shows less tendency of discoloration in combination with the materials normally causing such trouble with Heliotropine. It is also used in flavor compositions, particularly in Raspberty and Cherry, two flavors which are commonly used as targets for fantasy fragrances for Iipst ick perfumes. As a sweetener, it modifies Anise and Anethole in licorice flavor compositions, and it is generally used in smaller amounts in many imitation fruit flavors for baked goods or hard candy, where heat stability is essential.

Preparation

By condensing acetone with anisaldehyde to yield anisylidene acetone and subsequent hydrogenation in the presence of Pd catalyst. It can also be prepared from Methyl vinyl ketone by catalytic condensation with Phenol, followed by Methylation.

Definition

ChEBI: 4-(4-Methoxyphenyl)-2-butanone is a member of methoxybenzenes.

Aroma threshold values

Aroma characteristics at 5.0%: sweet, fruity, woody, powdery, honey, vanilla, raspberry and ionone-like.

Taste threshold values

Taste characteristics at 40 ppm: floral, woody, ionone, raspberry, fruity, spice and berry.

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 951, 1992 DOI: 10.1016/S0040-4039(00)91585-5

Safety Profile

Low oral and skin toxicity. A flammable liquid. When heated to decomposition it emits acrid smoke and irritating fumes.

4-(4-Methoxyphenyl)-2-butanone Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-(4-Methoxyphenyl)-2-butanone manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
4-(4-Methoxyphenyl)-2-butanone 104-20-1
Price
US $45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-12-09
Hebei Weibang Biotechnology Co., Ltd
Product
4-(4-Methoxyphenyl)-2-butanone 104-20-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-28
Shandong Deshang Chemical Co., Ltd.
Product
4-(4-Methoxyphenyl)-2-butanone 104-20-1
Price
US $9.30-7.20/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
10 tons
Release date
2024-06-21

104-20-1, 4-(4-Methoxyphenyl)-2-butanoneRelated Search:

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