5-BROMO-2-METHYL-1H-BENZIMIDAZOLE
Uses- Product Name
- 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE
- CAS No.
- 1964-77-8
- Chemical Name
- 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE
- Synonyms
- 2-Methy-5-bromobenzimidazole;5-bromo-2-methybenzimidazole;5-BROMO-2-METHYLBENZIMIDAZOLE;5-Bromo-2-methylbenzoimidazole;5-BROMO-2-METHYL-1H-BENZIMIDAZOLE;5-Bromo-2-methyl-1H-benzoimidazole;1H-BenziMidazole, 6-broMo-2-Methyl-;5-broMo-2-Methyl-1H-1,3-benzodiazole;5-BROMO-2-METHYL-1H-BENZ(D)IMIDAZOLE;6-bromo-2-methyl-1H-benzo[d]imidazole
- CBNumber
- CB7733608
- Molecular Formula
- C8H7BrN2
- Formula Weight
- 211.06
- MOL File
- 1964-77-8.mol
5-BROMO-2-METHYL-1H-BENZIMIDAZOLE Property
- Melting point:
- 214-215 °C
- Boiling point:
- 397.3±15.0 °C(Predicted)
- Density
- 1.654±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- 10.50±0.10(Predicted)
- Appearance
- Light yellow to yellow Solid
- InChI
- InChI=1S/C8H7BrN2/c1-5-10-7-3-2-6(9)4-8(7)11-5/h2-4H,1H3,(H,10,11)
- InChIKey
- FHDFUQGJYYGLHJ-UHFFFAOYSA-N
- SMILES
- C1(C)NC2=CC(Br)=CC=C2N=1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- ANV00243
- Product name
- 5-Bromo-2-methyl-1<I>H</I>-benzimidazole
- Purity
- Aldrich<SUP>CPR</SUP>
- Packaging
- 1 g
- Price
- $185
- Updated
- 2025/07/31
- Product number
- B697035
- Product name
- 5-Bromo-2-methylbenzoimidazole
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- J54672
- Product name
- 5-Bromo-2-methyl-1H-benzimidazole
- Packaging
- 10g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 119046
- Product name
- 5-Bromo-2-methyl-1H-benzo[d]imidazole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $82
- Updated
- 2021/12/16
- Product number
- FB44915
- Product name
- 5-Bromo-2-methyl-1H-benzo[d]imidazole
- Packaging
- 2g
- Price
- $200
- Updated
- 2021/12/16
5-BROMO-2-METHYL-1H-BENZIMIDAZOLE Chemical Properties,Usage,Production
Uses
5-Bromo-2-methyl-1H-benzo[D]imidazole is a benzo[D]imidazole derivative. Benzimidazole compounds possess biological activities such as anti-HIV-1 activity, anti-tumor activity, anti-cell proliferation activity, anti-parasitic activity, anti-inflammatory activity, antioxidant activity, and anti-epileptic activity. In addition, these compounds are also used as metal ligands. Therefore, the synthesis of these compounds has attracted considerable attention from chemists.
Synthesis
78-39-7
1575-37-7
1964-77-8
GENERAL METHOD: A mixture of 4-bromophthalimide (1.0 mmol), triethyl orthoacetate (1.2 mmol) and ZrCl4 (0.1 mmol) in 10 mL of methanol was stirred at room temperature for 3 hours. Upon completion of the reaction, the progress was monitored by TLC and the solvent was removed by concentration under reduced pressure. The crude product was purified by silica gel column chromatography with an eluent ratio of petroleum ether/ethyl acetate (4:1 to 1:1, v/v) to afford the target compound 5-bromo-2-methyl-1H-benzo[D]imidazole.
References
[1] European Journal of Medicinal Chemistry, 2015, vol. 90, p. 241 - 250
5-BROMO-2-METHYL-1H-BENZIMIDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE manufacturers
- Product
- 5-Bromo-2-Methyl-1H-Benzimidazole 1964-77-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 5-Bromo-2-Methyl-1H-Benzimidazole 1964-77-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE 1964-77-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-20