ChemicalBook > CAS DataBase List > 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE

5-BROMO-2-METHYL-1H-BENZIMIDAZOLE

Uses

Product Name: 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE
CAS No.: 1964-77-8
Chemical Name: 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE
Synonyms: 2-Methy-5-bromobenzimidazole;5-bromo-2-methybenzimidazole;5-BROMO-2-METHYLBENZIMIDAZOLE;5-Bromo-2-methylbenzoimidazole;5-BROMO-2-METHYL-1H-BENZIMIDAZOLE;5-Bromo-2-methyl-1H-benzoimidazole;1H-BenziMidazole, 6-broMo-2-Methyl-;5-broMo-2-Methyl-1H-1,3-benzodiazole;5-BROMO-2-METHYL-1H-BENZ(D)IMIDAZOLE;6-bromo-2-methyl-1H-benzo[d]imidazole
CBNumber: CB7733608
Molecular Formula: C8H7BrN2
Formula Weight: 211.06
MOL File: 1964-77-8.mol

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5-BROMO-2-METHYL-1H-BENZIMIDAZOLE Property

Melting point:: 214-215 °C
Boiling point:: 397.3±15.0 °C(Predicted)
Density: 1.654±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: solid
pka: 10.50±0.10(Predicted)
Appearance: Light yellow to yellow Solid
InChI: InChI=1S/C8H7BrN2/c1-5-10-7-3-2-6(9)4-8(7)11-5/h2-4H,1H3,(H,10,11)
InChIKey: FHDFUQGJYYGLHJ-UHFFFAOYSA-N
SMILES: C1(C)NC2=CC(Br)=CC=C2N=1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: ANV00243
Product name: 5-Bromo-2-methyl-1H-benzimidazole
Purity: AldrichCPR
Packaging: 1 g
Price: $185
Updated: 2025/07/31

TRC

Product number: B697035
Product name: 5-Bromo-2-methylbenzoimidazole
Packaging: 500mg
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: J54672
Product name: 5-Bromo-2-methyl-1H-benzimidazole
Packaging: 10g
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 119046
Product name: 5-Bromo-2-methyl-1H-benzo[d]imidazole
Purity: 95+%
Packaging: 1g
Price: $82
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB44915
Product name: 5-Bromo-2-methyl-1H-benzo[d]imidazole
Packaging: 1g
Price: $120
Updated: 2021/12/16

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5-BROMO-2-METHYL-1H-BENZIMIDAZOLE Chemical Properties,Usage,Production

Uses

5-Bromo-2-methyl-1H-benzo[D]imidazole is a benzo[D]imidazole derivative. Benzimidazole compounds possess biological activities such as anti-HIV-1 activity, anti-tumor activity, anti-cell proliferation activity, anti-parasitic activity, anti-inflammatory activity, antioxidant activity, and anti-epileptic activity. In addition, these compounds are also used as metal ligands. Therefore, the synthesis of these compounds has attracted considerable attention from chemists.

Synthesis

78-39-7

1575-37-7

1964-77-8

GENERAL METHOD: A mixture of 4-bromophthalimide (1.0 mmol), triethyl orthoacetate (1.2 mmol) and ZrCl4 (0.1 mmol) in 10 mL of methanol was stirred at room temperature for 3 hours. Upon completion of the reaction, the progress was monitored by TLC and the solvent was removed by concentration under reduced pressure. The crude product was purified by silica gel column chromatography with an eluent ratio of petroleum ether/ethyl acetate (4:1 to 1:1, v/v) to afford the target compound 5-bromo-2-methyl-1H-benzo[D]imidazole.

References

[1] European Journal of Medicinal Chemistry, 2015, vol. 90, p. 241 - 250

5-BROMO-2-METHYL-1H-BENZIMIDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-2-METHYL-1H-BENZIMIDAZOLE Suppliers

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View Lastest Price from 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-Bromo-2-Methyl-1H-Benzimidazole 1964-77-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-Bromo-2-Methyl-1H-Benzimidazole 1964-77-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE 1964-77-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-20

1964-77-8, 5-BROMO-2-METHYL-1H-BENZIMIDAZOLERelated Search:

5-Bromo-1H-Benzo[d]Imidazole-2-Carboxylic Acid 6-BROMO-1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER 2-(HYDROXYMETHYL)-5-BROMO-1H-BENZOIMIDAZOLE 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE 6-Bromo-1-methyl-1H-benzimidazole 1H-BENZIMIDAZOLE, 6-BROMO-2-(TRIFLUOROMETHYL)- 3-(5-BROMO-1H-BENZOIMIDAZOL-2-YL)-PROPAN-1-OL 5-bromo-2-(chloromethyl)-1H-benzo[d]imidazole 4-BROMO-2-METHYL-1H-BENZIMIDAZOLE 5-BROMO-6-METHYL-1H-BENZIMIDAZOLE 4-(5-BROMO-1 H-BENZOIMIDAZOL-2-YL)-PHENYLAMINE 5-BROMO-1H-BENZIMIDAZOLE-2-CARBOXYLIC ACID ETHYL ESTER 3-(5-BROMO-1 H-BENZOIMIDAZOL-2-YL)-PHENYLAMINE 1-(5-BROMO-1H-BENZOIMIDAZOL-2-YL)-ETHANOL 6-BROMO-2-(PIPERIDIN-4-YL)-1H-BENZO[D]IMIDAZOLE 5-Bromobenzimidazole-2-carboxaldehyde 5-BROMO-1-METHYL-1H-BENZIMIDAZOLE AURORA KA-316

5-BROMO-2-METHYL-1H-BENZIMIDAZOLE

5-BROMO-2-METHYL-1H-BENZO[D]IMIDAZOLE

5-BROMO-2-METHYLBENZIMIDAZOLE

5-BROMO-2-METHYL-1H-BENZ(D)IMIDAZOLE

5-Bromo-2-methylbenzoimidazole

1H-BenziMidazole, 6-broMo-2-Methyl-

5-broMo-2-Methyl-1H-1,3-benzodiazole

5-Bromo-2-methyl-1H-benzoimidazole

5-bromo-2-methybenzimidazole

2-Methy-5-bromobenzimidazole

6-bromo-2-methyl-1H-benzo[d]imidazole

5-Bromo-2-methyl-1H-benzimidazole

1964-77-8

C8H7BrN2