ChemicalBook > CAS DataBase List > CIS-ACONITIC ANHYDRIDE

CIS-ACONITIC ANHYDRIDE

Product Name: CIS-ACONITIC ANHYDRIDE
CAS No.: 6318-55-4
Chemical Name: CIS-ACONITIC ANHYDRIDE
Synonyms: aconitic anhydride;CIS-ACONITIC ANHYDRIDE;Cis-AconiticAnhydride98%;cis-Aconitic anhydride 95%;CIS-ACONITIC ACID ANHYDRIDE;cis-Aconitic anhydride;(2,5-Dioxo-3-furyl)acetic acid;2-(2,5-Dioxo-3-furyl)acetic acid;2-(2,5-dioxofuran-3-yl)aceticaci;2-(2,5-diketo-3-furyl)acetic acid
CBNumber: CB7739206
Molecular Formula: C6H4O5
Formula Weight: 156.09
MOL File: 6318-55-4.mol

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CIS-ACONITIC ANHYDRIDE Property

Melting point:: 75-78 °C (lit.)
Boiling point:: 397.8±25.0 °C(Predicted)
Density: 1.621±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 3?+-.0.10(Predicted)
Sensitive: Moisture Sensitive
BRN: 127575
CAS DataBase Reference: 6318-55-4(CAS DataBase Reference)
EPA Substance Registry System: 3-Furanacetic acid, 2,5-dihydro-2,5-dioxo- (6318-55-4)

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Safety

Hazard Codes: C
Risk Statements: 34
Safety Statements: 26-36/37/39-45
RIDADR: UN 3261 8/PG 2
WGK Germany: 3
F: 10-21
TSCA: Yes
HazardClass: 8
PackingGroup: III
HS Code: 2917198090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 217808
Product name: cis-Aconitic anhydride
Purity: 95%
Packaging: 1g
Price: $73.05
Updated: 2025/07/31

Sigma-Aldrich

Product number: 217808
Product name: cis-Aconitic anhydride
Purity: 95%
Packaging: 5g
Price: $267
Updated: 2025/07/31

TRC

Product number: A190225
Product name: cis-Aconitic anhydride
Packaging: 500mg
Price: $65
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0028910
Product name: CIS-ACONITIC ANHYDRIDE
Purity: 95.00%
Packaging: 50G
Price: $3627.87
Updated: 2021/12/16

AK Scientific

Product number: X3624
Product name: cis-Aconitic anhydride
Packaging: 5g
Price: $495
Updated: 2021/12/16

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CIS-ACONITIC ANHYDRIDE Chemical Properties,Usage,Production

Uses

cis-Aconitic anhydride is used in the preparation of poly(amino acid)-containing copolymers with gradient pH-sensitive side groups initiated by the amino groups in methoxy poly(ethylene glycol)-block-poly(L-lysine). It is also involved in the preparation of pH-sensitive anti-tumor prodrug nanoparticles by conjugation with D-alfa-tocopheryl polyethylene glycol 1000 succinate (TPGS).

Purification Methods

Reflux it in xylene (7.5 parts) for 1hour, then evaporate and recrystallise the residue from *C6H6. Alternatively, reflux it in Ac2O, evaporate and recrystallise from *C6H6. It is sensitive to moisture. [IR: Groth & Dahlén Acta Chem Scand 21 291 1967, Malachowski & Maslowski Chem Ber 61 2523 1928, NMR: Gawron & Mahajan Biochemistry 5 2335 1966.] [Beilstein 18/8 V 530.]

CIS-ACONITIC ANHYDRIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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6318-55-4, CIS-ACONITIC ANHYDRIDERelated Search:

(E)-Ethylidenesuccinic acid 3-Methyl-2-buten-1-ol 3,3-Dimethylacrylic acid 3-METHYL-2(5H)-FURANONE VINYLACETIC ACID METHYL CROTONATE CIS-BUTENEDIOIC ANHYDRIDE 2(5H)-Furanone 3-PENTENOIC ACID MONO-METHYL SUCCINATE 3-METHYL-3-BUTEN-1-OL ANGELIC ACID TRANS-2-PENTEN-1-OL TRANS-2-PENTENOIC ACID Methyl 4-oxobutanoate METHYL 2-PENTENOATE CIS-ACONITIC ANHYDRIDE Pent-2-ene-1,5-dioic acid Aconitic Anhydride

2-(2,5-diketo-3-furyl)acetic acid

2-(2,5-dioxofuran-3-yl)acetic acid

2-(2,5-dioxofuran-3-yl)ethanoic acid

cis-Aconitic anhydride,cis-Propene-1,2,3-tricarboxylic anhydride

cis-Prop-1-ene-1,2,3-tricarboxylic acid anhydride, (2,5-Dihydro-2,5-dioxofur-3-yl)acetic acid

2-(2,5-dioxo-2,5-dihydrofuran-3-yl)acetic acid

(2,5-Dihydro-2,5-dioxofur-3-yl)acetic acid

3-(Carboxymethyl)-2,5-dihydro-2,5-dioxofuran, cis-Aconitic anhydride , cis-Prop-1-ene-1,2,3-tricarboxylic anhydride

cis-Aconitic anhydride 95%

2-(2,5-Dioxo-2,5-dihydrofuran-3-yl)

aconitic anhydride

cis-ACONITIC ANHYDRIDE extrapure for biochemistry

(2,5-Dioxo-3-furyl)acetic acid

2,5-Dihydro-2,5-dioxo-3-furanacetic acid

2,5-Dioxo-2,5-dihydrofuran-3-acetic acid

2-(2,5-dioxo-2,5-dihydrofuran-3-yl)acetic acid, cis

Cis-AconiticAnhydride98%

CIS-ACONITIC ACID ANHYDRIDE

CIS-ACONITIC ANHYDRIDE

CIS-PROPENE-1,2,3-TRICARBOXYLIC ACID ANHYDRIDE

CIS-PROPENE-1,2,3-TRICARBOXYLIC ANHYDRIDE

2,5-dihydro-2,5-dioxofuran-3-acetic acid

2,5-dihydro-2,5-dioxo-3-furanaceticaci

3-Furanacetic acid, 2,5-dihydro-2,5-dioxo-

2-(2,5-Dioxo-3-furyl)acetic acid

2-(2,5-dioxofuran-3-yl)aceticaci

<i>cis</i>-Aconitic anhydride

6318-55-4

CARBOXYLIC ACID

Organic Building Blocks

Carboxylic Acid Anhydrides

Carbonyl Compounds

Building Blocks