CIS-ACONITIC ANHYDRIDE
- Product Name
- CIS-ACONITIC ANHYDRIDE
- CAS No.
- 6318-55-4
- Chemical Name
- CIS-ACONITIC ANHYDRIDE
- Synonyms
- aconitic anhydride;CIS-ACONITIC ANHYDRIDE;Cis-AconiticAnhydride98%;cis-Aconitic anhydride 95%;CIS-ACONITIC ACID ANHYDRIDE;(2,5-Dioxo-3-furyl)acetic acid;2-(2,5-Dioxo-3-furyl)acetic acid;2-(2,5-dioxofuran-3-yl)aceticaci;2-(2,5-diketo-3-furyl)acetic acid;2-(2,5-dioxofuran-3-yl)acetic acid
- CBNumber
- CB7739206
- Molecular Formula
- C6H4O5
- Formula Weight
- 156.09
- MOL File
- 6318-55-4.mol
CIS-ACONITIC ANHYDRIDE Property
- Melting point:
- 75-78 °C (lit.)
- Boiling point:
- 397.8±25.0 °C(Predicted)
- Density
- 1.621±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 3?+-.0.10(Predicted)
- Sensitive
- Moisture Sensitive
- BRN
- 127575
- CAS DataBase Reference
- 6318-55-4(CAS DataBase Reference)
- EPA Substance Registry System
- 3-Furanacetic acid, 2,5-dihydro-2,5-dioxo- (6318-55-4)
Safety
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 3261 8/PG 2
- WGK Germany
- 3
- F
- 10-21
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 2917198090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
N-Bromosuccinimide Price
- Product number
- 217808
- Product name
- cis-Aconitic anhydride
- Purity
- 95%
- Packaging
- 1g
- Price
- $44.58
- Updated
- 2024/03/01
- Product number
- 217808
- Product name
- cis-Aconitic anhydride
- Purity
- 95%
- Packaging
- 5g
- Price
- $258
- Updated
- 2024/03/01
- Product number
- A16006
- Product name
- cis-Aconitic anhydride, 98%
- Packaging
- 1g
- Price
- $47.65
- Updated
- 2024/03/01
- Product number
- A16006
- Product name
- cis-Aconitic anhydride, 98%
- Packaging
- 5g
- Price
- $197
- Updated
- 2024/03/01
- Product number
- A16006
- Product name
- cis-Aconitic anhydride, 98%
- Packaging
- 25g
- Price
- $746
- Updated
- 2024/03/01
CIS-ACONITIC ANHYDRIDE Chemical Properties,Usage,Production
Uses
cis-Aconitic anhydride is used in the preparation of poly(amino acid)-containing copolymers with gradient pH-sensitive side groups initiated by the amino groups in methoxy poly(ethylene glycol)-block-poly(L-lysine). It is also involved in the preparation of pH-sensitive anti-tumor prodrug nanoparticles by conjugation with D-alfa-tocopheryl polyethylene glycol 1000 succinate (TPGS).
Purification Methods
Reflux it in xylene (7.5 parts) for 1hour, then evaporate and recrystallise the residue from *C6H6. Alternatively, reflux it in Ac2O, evaporate and recrystallise from *C6H6. It is sensitive to moisture. [IR: Groth & Dahlén Acta Chem Scand 21 291 1967, Malachowski & Maslowski Chem Ber 61 2523 1928, NMR: Gawron & Mahajan Biochemistry 5 2335 1966.] [Beilstein 18/8 V 530.]