2,4-Dichloroaniline Property

Melting point:

59-62 °C (lit.) 60-65 °C

Boiling point:

245 °C (lit.)

Density 

1.567

vapor pressure 

1hPa at 78℃

refractive index 

1.6000 (estimate)

Flash point:

115°C

storage temp. 

0-6°C

solubility 

methanol: soluble, clear, very faintly brownish-yellow

pka

2.05(at 22℃)

form 

Crystalline Powder

Specific Gravity

1.567 (20℃)

color 

White to beige

Water Solubility 

Insoluble, <0.1 g/100 mL at 23 ºC

BRN 

386422

LogP

2.78 at 20℃

CAS DataBase Reference

554-00-7(CAS DataBase Reference)

NIST Chemistry Reference

Benzenamine, 2,4-dichloro-(554-00-7)

EPA Substance Registry System

2,4-Dichloroaniline (554-00-7)

Safety

Hazard Codes 

T,N,Xi

Risk Statements 

23/24/25-33-50/53

Safety Statements 

28-36/37-45-60-61-28A

RIDADR 

UN 3442 6.1/PG 2

WGK Germany 

3

RTECS 

BX2600000

F 

8-9-23

Hazard Note 

Toxic/Irritant

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

II

HS Code 

29214210

Hazardous Substances Data

554-00-7(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

2,4-Dichloroaniline Chemical Properties,Usage,Production

Chemical Properties

pale grey or beige-brown to red-brown crystalline. Melting point 63°C, boiling point 245°C, relative density 1.567 (20/4°C), soluble in organic solvents such as ethanol, ether and acids. Slightly soluble in water. The color will be darkened in air.

Uses

2,4-Dichloroaniline is used as an intermediate in the synthesis of dyestuffs, pigments, and pesticides.

Uses

2,4-Dichloroaniline may be used as an analytical reference standard for the determination of the analyte in water samples by ultrasound-assisted ionic liquid dispersive liquid-phase micro-extraction, capillary electrophoresis with electrochemical and fluorescence detection and gas chromatography-mass spectrometry (GC-MS), respectively.

Uses

2,4-Dichloroaniline is used as a raw material for the synthesis of anti-infective drug ciprofloxacin, pesticide fungicide Imibenconazole, herbicide (PUMA) and dyes.

Preparation

2,4-Dichloroaniline is synthesized from acetanilide by chlorination and hydrolysis.

Definition

ChEBI: 2,4-dichloroaniline is a dichloroaniline carrying chloro substituents at positions 2 and 4.

General Description

Beige crystals.

Air & Water Reactions

2,4-Dichloroaniline may be sensitive to exposure to air. Insoluble in water.

Reactivity Profile

2,4-Dichloroaniline is incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents.

Fire Hazard

Flash point data for 2,4-Dichloroaniline are not available. 2,4-Dichloroaniline is probably combustible.