Ethyltriphenylphosphonium bromide
- Product Name
- Ethyltriphenylphosphonium bromide
- CAS No.
- 1530-32-1
- Chemical Name
- Ethyltriphenylphosphonium bromide
- Synonyms
- TEP;Ethyl triphenyl phosphine bromide;ethyltriphenylphosphanium bromide;AD182;ETPPB;tbepb;ETPPBR;Ethyl triphenyl pho;TEP (oniuM coMpound);Antioxidants Impurity 15
- CBNumber
- CB7752854
- Molecular Formula
- C20H20BrP
- Formula Weight
- 371.25
- MOL File
- 1530-32-1.mol
Ethyltriphenylphosphonium bromide Property
- Melting point:
- 203-205 °C(lit.)
- Boiling point:
- 240℃[at 101 325 Pa]
- Density
- 1.38[at 20℃]
- vapor pressure
- 0-0.1Pa at 20-25℃
- Flash point:
- 200 °C
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- 174g/l soluble
- form
- Crystalline Powder
- color
- White to off-white
- Water Solubility
- 120 g/L (23 ºC)
- Sensitive
- Hygroscopic
- BRN
- 3599630
- InChIKey
- JHYNXXDQQHTCHJ-UHFFFAOYSA-M
- LogP
- -0.69--0.446 at 35℃
- CAS DataBase Reference
- 1530-32-1(CAS DataBase Reference)
- EPA Substance Registry System
- Phosphonium, ethyltriphenyl-, bromide (1530-32-1)
Safety
- Hazard Codes
- Xn,N,Xi
- Risk Statements
- 22-51/53-36/37/38-21/22
- Safety Statements
- 61-36/37/39-26-36
- RIDADR
- UN 3077 9/PG 3
- WGK Germany
- 2
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29310095
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H318Causes serious eye damage
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- E50604
- Product name
- Ethyltriphenylphosphonium bromide
- Purity
- 99%
- Packaging
- 25g
- Price
- $36.74
- Updated
- 2025/07/31
- Product number
- E50604
- Product name
- Ethyltriphenylphosphonium bromide
- Purity
- 99%
- Packaging
- 100g
- Price
- $128.78
- Updated
- 2025/07/31
- Product number
- E0382
- Product name
- Ethyltriphenylphosphonium Bromide
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $29
- Updated
- 2025/07/31
- Product number
- E0382
- Product name
- Ethyltriphenylphosphonium Bromide
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 100g
- Price
- $74
- Updated
- 2025/07/31
- Product number
- 15-2301
- Product name
- Ethyltriphenylphosphonium bromide, 99%
- Packaging
- 25g
- Price
- $55
- Updated
- 2024/03/01
Ethyltriphenylphosphonium bromide Chemical Properties,Usage,Production
Chemical Properties
White to off-white crystalline powder
Uses
suzuki reaction
Uses
Ethyltriphenylphosphonium Bromide is used as a wittig reagent. Ethyltriphenylphosphonium Bromide and other phosphonium salts show antiviral activity.
Uses
Ethyltriphenylphosphonium Bromide (ETPB) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.
- Ethyltriphenylphosphonium bromide acts as a reactant in the synthesis of D-amino acids from L-cysteine-derived thiazolidines, Leiodolide A through aldol reactions and Horner-Wadsworth-Emmons olefination.
- It is also used in the preparation of cycloalkanoindolines through diastereoselective intramolecular inimo-ene reactions.
- it is used as a reagent in solid-state metathesis polycondensation to prepare alkyl-dipropenylthiophene monomers.
- Mizoroki-Heck cyclization and cascading Tsuji-Trost cyclization reactions.
Uses
PTC catalyst
Flammability and Explosibility
Not classified
reaction suitability
reaction type: C-C Bond Formation
Synthesis
74-96-4
603-35-0
1530-32-1
In a 1500 mL three-necked flask, 54 g (0.5 mol) of ethyl bromide, 210 g (0.8 mol) of triphenylphosphine and 1000 mL of toluene were added sequentially. A reflux condenser tube was installed, magnetic stirring was turned on and the reaction was heated to reflux state and kept at reflux for 10 hours. Upon completion of the reaction, the reaction system was naturally cooled to 50 °C and a large amount of white solid was observed to precipitate. The solid product was collected by filtration through a Brinell funnel and the filter cake was washed with toluene three times (50 mL each time). The resulting solid was transferred to a vacuum drying oven and dried at 50 °C until constant weight, resulting in 170.4 g of ethyltriphenylphosphonium bromide in 91.8% yield.
Purification Methods
Recrystallise it from H2O and dry it in high vacuum at 100o. IR has bands at 1449, 1431 and 997cm-1 . [Wittig & Wittenberg Justus Liebigs Ann Chem 606 1 1957, Bergmann & Dusza J Org Chem 23 1245 1958, Beilstein 16 IV 982.]
References
[1] Journal of Fluorine Chemistry, 2002, vol. 113, # 2, p. 177 - 183
[2] Pharmazie, 1999, vol. 54, # 1, p. 26 - 30
[3] Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1989, vol. <2> 38, # 12, p. 2553 - 2556
[4] Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1989, vol. <2> 38, # 12, p. 2789 - 2792
[5] Journal of the American Chemical Society, 1980, vol. 102, p. 2437
Ethyltriphenylphosphonium bromide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ethyltriphenylphosphonium bromide manufacturers
- Product
- Ethyl(triphenyl)phosphonium bromide 1530-32-1
- Price
- US $50.00-10.00/kg
- Min. Order
- 1kg
- Purity
- 99%，Electronic grade(Single metal impurity≤ 100ppb) or pharmaceutical grade
- Supply Ability
- 100kg
- Release date
- 2025-09-02
- Product
- Ethyltriphenylphosphonium bromide 1530-32-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-02-23
- Product
- Ethyltriphenylphosphonium bromide 1530-32-1
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-10-24