Uses
ChemicalBook > CAS DataBase List > 1-Methyl-aminomethyl naphthalene

1-Methyl-aminomethyl naphthalene

Uses
Product Name
1-Methyl-aminomethyl naphthalene
CAS No.
14489-75-9
Chemical Name
1-Methyl-aminomethyl naphthalene
Synonyms
CL134;ene-1-methyL;N-Methyl Naph;AURORA KA-7760;TIMTEC-BB SBB005765;1-Methyl-aminomethyl;Terbinafine EP Impurity A;N-methyl hydrochloric salt;N-methyl-1-menaphthylamine;N-METHYL-1-NAPHTHALENEAMINE
CBNumber
CB7758164
Molecular Formula
C12H13N
Formula Weight
171.24
MOL File
14489-75-9.mol
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1-Methyl-aminomethyl naphthalene Property

Melting point:
189.5-190 °C
Boiling point:
104 °C
Density 
1,05 g/cm3
refractive index 
1.6160-1.6190
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
clear liquid
pka
9.38±0.10(Predicted)
color 
Colorless to Orange to Green
PH
10.71 at 24℃ and 10g/L
InChI
InChI=1S/C12H13N/c1-13-9-11-7-4-6-10-5-2-3-8-12(10)11/h2-8,13H,9H2,1H3
InChIKey
MQRIUFVBEVFILS-UHFFFAOYSA-N
SMILES
C1(CNC)=C2C(C=CC=C2)=CC=C1
CAS DataBase Reference
14489-75-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HS Code 
2921.49.5000
HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M0983
Product name
N-Methyl-1-naphthylmethylamine
Purity
>98.0%(T)
Packaging
1g
Price
$34
Updated
2025/07/31
TCI Chemical
Product number
M0983
Product name
N-Methyl-1-naphthylmethylamine
Purity
>98.0%(T)
Packaging
5g
Price
$103
Updated
2025/07/31
TRC
Product number
M323140
Product name
Methyl-1-naphthalenemethylamine
Packaging
500mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
F353
Product name
N-Methyl-1-naphthylmethylamine
Packaging
500g
Price
$561
Updated
2021/12/16
AK Scientific
Product number
J51771
Product name
N-Methyl-1-naphthylmethylamine
Packaging
25g
Price
$38
Updated
2021/12/16
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1-Methyl-aminomethyl naphthalene Chemical Properties,Usage,Production

Uses

1-Methyl-aminomethyl naphthalene has been used as reagent for the determination of isocyanates in air by UV or fluorescence detection. 1-Methyl-aminomethyl naphthalene has been used in the preparation of key intermediate required for the synthesis of terbinafine.

Chemical Properties

Yellow Oil

Uses

Terbinafine EP Impurity A. Terbinafine BP Impurity A. Terbinafine USP Related Compound A

Synthesis

1498015-90-9

14489-75-9

The crude product N-methyl-N-(1-naphthylmethyl)formamide prepared according to step (a) was suspended in 300 mL of 20% aqueous sodium hydroxide solution and the reaction was heated at 60-70°C for 7 hours. Upon completion of the reaction, the mixture was cooled to 25 °C and subsequently extracted with toluene (2 x 200 mL). The toluene extracts were combined and back-extracted with 3N hydrochloric acid (2 x 300 mL). The aqueous phase was decolorized with activated carbon and the pH was adjusted with 20% aqueous sodium hydroxide to 10.0. The released free base was extracted with toluene, and the toluene layers were combined and distilled to remove the solvent to give 86 g of crude product. Finally, 82 g (85% yield) of pure N-methyl-1-naphthalenemethylamine was obtained by high vacuum distillation purification.

References

[1] Patent: WO2004/80945, 2004, A1. Location in patent: Page 8
[2] Patent: WO2004/80945, 2004, A1. Location in patent: Page 9-10

1-Methyl-aminomethyl naphthalene Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Methyl-aminomethyl naphthalene Suppliers

Aurora Fine Chemicals Ltd.
Tel
--
Fax
--
Email
aurora@aurorafinechemicals.com
Country
Austria
ProdList
6625
Advantage
72
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View Lastest Price from 1-Methyl-aminomethyl naphthalene manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
1-Methyl-aminomethyl naphthalene 14489-75-9
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-04-07
Hebei Chuanghai Biotechnology Co., Ltd
Product
1-Methyl-aminomethyl naphthalene 14489-75-9
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-29
Henan Aochuang Chemical Co.,Ltd.
Product
1-Methyl-aminomethyl naphthalene 14489-75-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-16

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