5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE

Product Name: 5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE
CAS No.: 131084-35-0
Chemical Name: 5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE
Synonyms: CS-1071;CP 94253;CP94253HCl;CP 94253 Free base;CP 94253 HYDROCHLORIDE;CP-94,253 dihydrochloride;3-(1,2,5,6-tetrahydro-4-pyridyl)-5-propoxypyrrolo[3,2-b]pyridine;5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine;5-Propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine;1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-
CBNumber: CB7761214
Molecular Formula: C15H19N3O
Formula Weight: 257.33
MOL File: 131084-35-0.mol

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5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE Property

Melting point:: >230°C (dec.)
Boiling point:: 442.9±45.0 °C(Predicted)
Density: 1.166
storage temp.: Desiccate at RT
solubility: H2O: soluble15mg/mL, clear
form: powder
pka: 14.37±0.40(Predicted)
color: white to beige

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0588
Product name: CP-94,253 dihydrochloride
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $119
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0588
Product name: CP-94,253 dihydrochloride
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $481
Updated: 2024/03/01

Tocris

Product number: 1317
Product name: CP94253hydrochloride
Purity: ≥98%(HPLC)
Packaging: 10
Price: $210
Updated: 2021/12/16

Tocris

Product number: 1317
Product name: CP94253hydrochloride
Purity: ≥98%(HPLC)
Packaging: 50
Price: $822
Updated: 2021/12/16

Usbiological

Product number: 255041
Product name: CP 94253 hydrochloride
Packaging: 10mg
Price: $466
Updated: 2021/12/16

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5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

CP 94253 Hydrochloride is a potent and selective serotonin 5-HT1B receptor agonist with anticonvulsant activity.

Definition

ChEBI: 5-propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine is a pyrrolopyridine.

Biological Activity

Potent, selective 5-HT 1B agonist (K i values are 89, 2, 860, 49 and 1,600 nM for 5-HT 1A , 5-HT 1B , 5-HT 1C , 5-HT 1D and 5-HT 2 receptors respectively). Centrally active upon systemic administration in vivo .

Biochem/physiol Actions

CP-94,253 is a potent and selective serotonin 5-HT1B receptor agonist with approximately 25x and 40x selectivity over the closely related 5-HT1D and 5-HT1A receptors. Ki values are 89, 2, 860, 49 and 1,600 nM for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D and 5-HT2 receptors respectively. CP-94,253 was found to be anxiolytic in animal models; dose-dependently enhanced reinforcing effects of cocaine (self-administration);and reduced food intake.

5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE Suppliers

China 20 Germany 3 United Kingdom 1 United States 7 Global 31

3B Pharmachem (Wuhan) International Co.,Ltd.

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Unipharm pharmaceutical industry Co., Ltd

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131084-35-0, 5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDERelated Search:

5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE 4-Azaindole 5-METHOXY-1H-PYRROLO[3,2-B]PYRIDINE

5-Propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine

CS-1071

5-PROPOXY-3-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-1H-PYRROLO[3,2-B]PYRIDINE HYDROCHLORIDE

CP 94253 HYDROCHLORIDE

CP94253HCl

5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridin hydrochloride

CP 94253

3- (1,2,5,6-Tetrahydro-4-pyridyl)-5-propoxypyrrolo[3, 2-b] pyridine hydrochloride

CP-94,253 dihydrochloride

3-(1,2,5,6-tetrahydro-4-pyridyl)-5-propoxypyrrolo[3,2-b]pyridine

5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine

1H-Pyrrolo[3,2-b]pyridine, 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-

5-propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine hydrochloride

CP 94253 Free base

131084-35-0

C15H20N3OCl

C15H19N3OHCl

Serotonin receptor