ChemicalBook > CAS DataBase List > (R)-LIPOIC ACID

(R)-LIPOIC ACID

Product Name
(R)-LIPOIC ACID
CAS No.
1200-22-2
Chemical Name
(R)-LIPOIC ACID
Synonyms
(R)-LIPOIC ACID;(R)-LIPOIC ACID;R-ALPHA-LIPOIC ACID;Thiogamma;Tiobe;Lipoec;Tiobec;(R)-(+)-α;ipoic acid;(R)-(+)-α-L
CBNumber
CB7765979
Molecular Formula
C8H14O2S2
Formula Weight
206.33
MOL File
1200-22-2.mol
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(R)-LIPOIC ACID Property

Melting point:
48-52 °C(lit.)
Boiling point:
185-195 °C(Press: 0.5 Torr)
alpha 
D23 +104° (c = 0.88 in benzene)
Density 
1.218±0.06 g/cm3(Predicted)
refractive index 
114 ° (C=1, EtOH)
Flash point:
>230 °F
storage temp. 
-20°C
solubility 
Acetonitrile (Slightly), Chloroform (Slightly), DMSO
form 
Solid
pka
5.4(at 25℃)
color 
Light Yellow to Yellow
optical activity
[α]20/D +104°, c = 1 in chloroform
Merck 
14,9326
LogP
2.160 (est)
CAS DataBase Reference
1200-22-2(CAS DataBase Reference)
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Safety

Risk Statements 
22-36/38
Safety Statements 
20-36-26-35
WGK Germany 
3
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
07039
Product name
(R)-(+)-α-Lipoic acid
Purity
≥98.0% (HPLC)
Packaging
10mg
Price
$77.6
Updated
2025/07/31
Sigma-Aldrich
Product number
04471
Product name
(R)-(+)-α-Lipoic acid
Purity
analytical standard
Packaging
100mg
Price
$214
Updated
2025/07/31
TCI Chemical
Product number
L0207
Product name
(R)-alpha-Lipoic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$101
Updated
2025/07/31
TCI Chemical
Product number
L0207
Product name
(R)-alpha-Lipoic Acid
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$183
Updated
2025/07/31
Cayman Chemical
Product number
27299
Product name
(R)-α-Lipoic Acid
Packaging
5g
Price
$86
Updated
2024/03/01
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(R)-LIPOIC ACID Chemical Properties,Usage,Production

Chemical Properties

Yellow Crystalline Solid

Uses

A fat-metabolism stimulator

Uses

α-Lipoic acid has been used as a reference standard for the analysis of α-lipoic acid in human plasma by high performance liquid chromatography coupled to electron capture detector (HPLC-ECD), in various food matrices and dietary supplements by HPLC combined with coulometric electrode array detector (CEAD) as well as electrospray ionization mass spectrometer (ESI-MS).
It may be used as a reference standard for the determination of α-lipoic acid in human urine by isocratic reversed-phase HPLC and in α-lipoic acid capsules by HPLC with chemiluminescence detection.

Definition

ChEBI: (R)-lipoic acid is the (R)-enantiomer of lipoic acid. A vitamin-like, C8 thia fatty acid with anti-oxidant properties. It has a role as a prosthetic group, a nutraceutical and a cofactor. It is a lipoic acid, a member of dithiolanes, a heterocyclic fatty acid and a thia fatty acid. It is functionally related to an octanoic acid. It is a conjugate acid of a (R)-lipoate. It is an enantiomer of a (S)-lipoic acid.

General Description

α-Lipoic acid is an antioxidant which is generally present in plants, animals and many other microorganisms.

Biochem/physiol Actions

(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. It is a biological antioxidant with prooxidant activities, its therapeutic potential is widely investigated, e.g. in the treatment for Alzheimer′s disease.

(R)-LIPOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (R)-LIPOIC ACID manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd
Product
(R)-(+)-1,2-Dithiolane-3-pentanoic acid 1200-22-2
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
Customise
Release date
2025-09-20
Shaanxi Dideu Medichem Co. Ltd
Product
(R)-(+)-1,2-Dithiolane-3-pentanoic acid 1200-22-2
Price
US $1.00-4.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200000KG
Release date
2025-09-02
Xi an Biohorlden Industry Trade Co Ltd
Product
R-Lipoic Acid 1200-22-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
200kg
Release date
2025-06-17

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