4-AMINO-N,N-DIMETHYLBENZYLAMINE

Product Name: 4-AMINO-N,N-DIMETHYLBENZYLAMINE
CAS No.: 6406-74-2
Chemical Name: 4-AMINO-N,N-DIMETHYLBENZYLAMINE
Synonyms: Nsc 207808;Einecs 229-033-0;p-Aminobenzyldimethylamine;4-DIMETHYLAMINOMETHYL-ANILINE;4-AMINO-N,N-DIMETHYLBENZYLAMINE;4-AMINOBENZYL-N,N-DIMETHYLAMINE;N,N-DiMethyl-4-aMinobenzylaMine;N-(4-AMINOBENZYL)-N,N-DIMETHYLAMINE;4-[(Dimethylamino)methyl]benzenamine;4-((dimmethylamino)methyl)benzenamine
CBNumber: CB7767069
Molecular Formula: C9H14N2
Formula Weight: 150.22
MOL File: 6406-74-2.mol

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4-AMINO-N,N-DIMETHYLBENZYLAMINE Property

Boiling point:: 231.8±15.0 °C(Predicted)
Density: 1.013±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 9.34±0.28(Predicted)
Appearance: Colorless to light yellow Solid-Liquid Mixture
EPA Substance Registry System: p-Aminobenzyldimethylamine (6406-74-2)

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Safety

HS Code: 2921599090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 074353
Product name: 4-Amino-N,N-dimethylbenzylamine
Purity: 95+%
Packaging: 1g
Price: $71
Updated: 2021/12/16

BroadPharm

Product number: BP-21733
Product name: 4-((dimethylamino)methyl)benzenamine
Packaging: 1g
Price: $59
Updated: 2021/12/16

Matrix Scientific

Product number: 074353
Product name: 4-Amino-N,N-dimethylbenzylamine
Purity: 95+%
Packaging: 5g
Price: $215
Updated: 2021/12/16

Matrix Scientific

Product number: 074353
Product name: 4-Amino-N,N-dimethylbenzylamine
Purity: 95+%
Packaging: 10g
Price: $374
Updated: 2021/12/16

AK Scientific

Product number: J53165
Product name: 4-Amino-N,N-dimethylbenzylamine
Packaging: 10g
Price: $220
Updated: 2021/12/16

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4-AMINO-N,N-DIMETHYLBENZYLAMINE Chemical Properties,Usage,Production

Uses

4-Amino-N,N-dimethylbenzylamine is a reagent in the reaction with methoxycarbonylphenyl isocyanate, in the synthesis of 4H-?3,?1-?benzoxazin-?4-?ones as potent alternate substrate inhibitors of human leukocyte elastase.

Synthesis

15184-96-0

6406-74-2

General procedure for the synthesis of 4-dimethylaminomethyl-aniline from N,N-dimethyl-4-nitrobenzylamine: to a solution of N,N-dimethyl-4-nitrobenzylamine (1 g, 5.55 mmol) in acetic acid (10 ml) was added activated iron powder (3 g), and the reaction mixture was stirred for 5 hr at 80 °C. After completion of the reaction, the reaction mixture was filtered; the filtrate was diluted with water and neutralized with 10% sodium hydroxide solution. The product was extracted with ethyl acetate, the organic layers were combined, dried with anhydrous sodium sulfate, filtered and the solvent was evaporated to give the crude product. The crude product was purified by silica gel column chromatography using chloroform/methanol (98:2, v/v) as eluent to give 4-dimethylaminomethyl-aniline (0.7 g, 85% yield).

References

[1] RSC Advances, 2015, vol. 5, # 58, p. 47125 - 47130
[2] Journal of Medicinal Chemistry, 2013, vol. 56, # 7, p. 2975 - 2990
[3] Patent: WO2006/123145, 2006, A1. Location in patent: Page/Page column 58
[4] European Journal of Medicinal Chemistry, 2014, vol. 86, p. 257 - 269
[5] Archiv der Pharmazie, 2014, vol. 347, # 12, p. 936 - 949

4-AMINO-N,N-DIMETHYLBENZYLAMINE Preparation Products And Raw materials

Raw materials

N-Bromosuccinimide Hydrazine hydrate 4-Nitrotoluene Iron chloride hexahydrate Dimethylamine

Preparation Products

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4-AMINO-N,N-DIMETHYLBENZYLAMINE Suppliers

China 107 Europe 1 India 1 The Netherlands 1 Ukraine 2 United Kingdom 4 United States 11 Global 127

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View Lastest Price from 4-AMINO-N,N-DIMETHYLBENZYLAMINE manufacturers

Career Henan Chemical Co

Product: 4-AMINO-N,N-DIMETHYLBENZYLAMINE 6406-74-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-07-03

6406-74-2, 4-AMINO-N,N-DIMETHYLBENZYLAMINERelated Search:

ACID YELLOW 7 4-AMINO-N,N-DIMETHYLBENZYLAMINE 3-AMINO-N,N-DIMETHYLBENZYLAMINE N,N-Dimethylbenzylamine N-CHLOROMETHYL-4-NITROPHTHALIMIDE (4-AMINO-PHENYL)-MORPHOLIN-4-YL-METHANONE 4-AMINO-N-METHYLPHTHALIMIDE LUCIFER YELLOW VS DILITHIUM SALT (4-NITROBENZYL)TRIMETHYLAMMONIUM CHLORIDE 6-AMINO-2-(2-HYDROXY-ETHYL)-1,3-DIOXO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-5-SULFONIC ACID N-(4-([2-OXO-5-(TRIFLUOROMETHYL)-1(2H)-PYRIDINYL]METHYL)PHENYL)-N'-PHENYLUREA N-METHYL-N'-(4-([2-OXO-5-(TRIFLUOROMETHYL)-1(2H)-PYRIDINYL]METHYL)PHENYL)UREA METHYL 2-([(4-([2-OXO-5-(TRIFLUOROMETHYL)-1(2H)-PYRIDINYL]METHYL)ANILINO)CARBONYL]SULFANYL)ACETATE N'-(4-CHLOROPHENYL)-N-(2-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)ETHYL)-N-[4-(DIMETHYLAMINO)BENZYL]UREA N-(4-([2-OXO-5-(TRIFLUOROMETHYL)-1(2H)-PYRIDINYL]METHYL)PHENYL)-N'-[4-(TRIFLUOROMETHOXY)PHENYL]UREA CHLOROETHYLCLONIDINE DIHYDROCHLORIDE 4-CHLORO-1-((4-NITROPHENYL)(4-PHENYLPIPERAZINYL)METHYLTHIO)BENZENE (8-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1-OXA-4,8-DIAZASPIRO[4.5]DEC-4-YL)(4-NITROPHENYL)METHANONE

p-Aminobenzyldimethylamine

N-(4-AMINOBENZYL)-N,N-DIMETHYLAMINE

N-[4-(AMINOMETHYL)PHENYL]-N,N-DIMETHYLAMINE

4-AMINOBENZYL-N,N-DIMETHYLAMINE

4-DIMETHYLAMINOMETHYL-ANILINE

4-AMINO-N,N-DIMETHYLBENZYLAMINE

4-((dimmethylamino)methyl)benzenamine

Benzenemethanamine, 4-amino-N,N-dimethyl- (9CI)

4-[(Dimethylamino)methyl]benzenamine

N,N-Dimethyl-4-aminobenzenemethaneamine

4-Amino-N,N-dimethylBenzenemethanamine

Benzenemethanamine, 4-amino-N,N-dimethyl-

Einecs 229-033-0

Nsc 207808

N,N-DiMethyl-4-aMinobenzylaMine

6406-74-2

AMINEPRIMARY

Amines and Anilines